Chromatin remodeling: a marriage between two families?

The Transcriptional Coactivators p300 and CBP Are Histone Acetyltransferases

1996 • 2,873 citations

A signature motif in transcriptional co-activators mediates binding to nuclear receptors

1997 • 2,100 citations

The CBP co-activator is a histone acetyltransferase

1996 • 1,773 citations

Tetrahymena Histone Acetyltransferase A: A Homolog to Yeast Gcn5p Linking Histone Acetylation to Gene Activation

1996 • 1,567 citations

Nuclear Receptor Coactivator ACTR Is a Novel Histone Acetyltransferase and Forms a Multimeric Activation Complex with P/CAF and CBP/p300

1997 • 1,472 citations

A p300/CBP-associated factor that competes with the adenoviral oncoprotein E1A

1996 • 1,457 citations

Steroid receptor coactivator-1 is a histone acetyltransferase

1997 • 1,245 citations

Yeast Gcn5 functions in two multisubunit complexes to acetylate nucleosomal histones: characterization of an Ada complex and the SAGA (Spt/Ada) complex.

1997 • 1,053 citations

Stimulation of GAL4 Derivative Binding to Nucleosomal DNA by the Yeast SWI/SNF Complex

1994 • 853 citations

Histone H3 and H4 N-termini interact with SIR3 and SIR4 proteins: A molecular model for the formation of heterochromatin in yeast

1995 • 778 citations

The TAFII250 Subunit of TFIID Has Histone Acetyltransferase Activity

1996 • 705 citations

Evolution of the SNF2 family of proteins: subfamilies with distinct sequences and functions

1995 • 702 citations

RSC, an Essential, Abundant Chromatin-Remodeling Complex

1996 • 680 citations

The retinoblastoma protein and BRG1 form a complex and cooperate to induce cell cycle arrest

1994 • 625 citations

ACF, an ISWI-Containing and ATP-Utilizing Chromatin Assembly and Remodeling Factor

1997 • 624 citations

A human homologue of Saccharomyces cerevisiae SNF2/SWI2 and Drosophila brm genes potentiates transcriptional activation by the glucocorticoid receptor.

1993 • 598 citations

Yeast SNF/SWI transcriptional activators and the SPT/SIN chromatin connection

1992 • 567 citations

Evidence that SNF2/SWI2 and SNF5 activate transcription in yeast by altering chromatin structure.

1992 • 535 citations

Chromatin-remodelling factor CHRAC contains the ATPases ISWI and topoisomerase II

1997 • 511 citations

Transcription-linked acetylation by Gcn5p of histones H3 and H4 at specific lysines

1997 • 480 citations

Roles of SWI1, SWI2, and SWI3 Proteins for Transcriptional Enhancement by Steroid Receptors

1992 • 477 citations

Repression domain of the yeast global repressor Tup1 interacts directly with histones H3 and H4.

1996 • 460 citations

Characterization of the CHD family of proteins

1997 • 389 citations

ISWI, a member of the SWl2/SNF2 ATPase family, encodes the 140 kDa subunit of the nucleosome remodeling factor

1995 • 366 citations

Efficient Transcriptional Silencing in Saccharomyces cerevisiae Requires a Heterochromatin Histone Acetylation Pattern

1996 • 363 citations

Two human homologues ofSaccharomyces cerevisiae SWI2/SNF2andDrosophila brahmaare transcriptional coactivators cooperating with the estrogen receptor and the retinoic acid receptor

1994 • 338 citations

Visualization of G1 chromosomes: a folded, twisted, supercoiled chromonema model of interphase chromatid structure.

1994 • 331 citations

Silencing factors participate in DNA repair and recombination in Saccharomyces cerevisiae

1997 • 330 citations

Two distinct yeast transcriptional activators require the function of the GCN5 protein to promote normal levels of transcription.

1992 • 302 citations

Essential Functional Interactions of SAGA, a Saccharomyces cerevisiae Complex of Spt, Ada, and Gcn5 Proteins, With the Snf/Swi and Srb/Mediator Complexes

1997 • 277 citations

Functional similarity and physical association between GCN5 and ADA2: putative transcriptional adaptors.

1994 • 276 citations

The SNF/SWI family of global transcriptional activators

1994 • 269 citations

Amino acid substitutions in the structured domains of histones H3 and H4 partially relieve the requirement of the yeast SWI/SNF complex for transcription.

1995 • 245 citations

Novel Substrate Specificity of the Histone Acetyltransferase Activity of HIV-1-Tat Interactive Protein Tip60

1997 • 234 citations

The hbrm and BRG-1 proteins, components of the human SNF/SWI complex, are phosphorylated and excluded from the condensed chromosomes during mitosis.

1996 • 228 citations

Persistent Site-Specific Remodeling of a Nucleosome Array by Transient Action of the SWI/SNF Complex

1996 • 227 citations

The Drosophila snr1 and brm proteins are related to yeast SWI/SNF proteins and are components of a large protein complex.

1995 • 225 citations

Role for ADA/GCN5 Products in Antagonizing Chromatin-Mediated Transcriptional Repression

1997 • 203 citations

Large-scale chromatin structural domains within mitotic and interphase chromosomes in vivo and in vitro

1989 • 194 citations

Catalytic activity of the yeast SWI/SNF complex on reconstituted nucleosome arrays

1997 • 184 citations

Characterization of Physical Interactions of the Putative Transcriptional Adaptor, ADA2, with Acidic Activation Domains and TATA-binding Protein

1995 • 184 citations

GAL4 Interacts with TATA-Binding Protein and Coactivators

1995 • 164 citations

Ligand-dependent interaction between the estrogen receptor and the human homologues of SWI2/SNF2

1997 • 160 citations

Glucocorticoid Receptor-Glucocorticoid Response Element Binding Stimulates Nucleosome Disruption by the SWI/SNF Complex

1997 • 159 citations

SNF2β-BRG1 is Essential for the Viability of F9 Murine Embryonal Carcinoma Cells

1997 • 156 citations

The Nucleosomal Array: Structure/Function Relationships

1996 • 155 citations

Histone acetylation in chromatin and chromosomes

1995 • 149 citations

Functional analysis of the DNA-stimulated ATPase domain of yeast SWI2/SNF2

1996 • 144 citations

The Yeast SWI-SNF Complex Facilitates Binding of a Transcriptional Activator to Nucleosomal Sites In Vivo

1997 • 139 citations

Role of histone tails in nucleosome remodeling by Drosophila NURF

1997 • 133 citations

Nucleosome Structural Changes Due to Acetylation

1994 • 133 citations

Multiple SWItches to turn on chromatin?

1996 • 131 citations

Identification of Native Complexes Containing the Yeast Coactivator/Repressor Proteins NGG1/ADA3 and ADA2

1997 • 113 citations

Yeast ADA2 protein binds to the VP16 protein activation domain and activates transcription.

1994 • 109 citations

ADR1 Activation Domains Contact the Histone Acetyltransferase GCN5 and the Core Transcriptional Factor TFIIB

1996 • 87 citations

Epistasis analysis of suppressor mutations that allow HO expression in the absence of the yeast SW15 transcriptional activator.

1994 • 81 citations

Interplay of yeast global transcriptional regulators Ssn6p-Tup1p and Swi-Snf and their effect on chromatin structure

1997 • 78 citations

Role of the Ada Adaptor Complex in Gene Activation by the Glucocorticoid Receptor

1997 • 74 citations

An uncertain silence

1997 • 65 citations

Functional Interaction between the DNA Binding Subunit Trimerization Domain of NF-Y and the High Mobility Group Protein HMG-I(Y)

1997 • 50 citations

Identification of a Member of a DNA-Dependent ATPase Family That Causes Interference with Silencing

1997 • 48 citations

Transcriptional activator components and poxvirus DNA-dependent ATPases comprise a single family

1993 • 48 citations

Protein complexes for remodeling chromatin

1997 • 34 citations

Adenovirus E1A Specifically Blocks SWI/SNF-Dependent Transcriptional Activation

1996 • 32 citations

High Mobility Group I Proteins Interfere with the Homeodomains Binding to DNA

1997 • 25 citations

Mutational and functional analysis of dominant SPT2 (SIN1) suppressor alleles in Saccharomyces cerevisiae.

1993 • 19 citations