Regulation of the antioxidant response element by protein kinase C-mediated phosphorylation of NF-E2-related factor 2

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

1983 • 11,902 citations

Oxidants, antioxidants, and the degenerative diseases of aging.

1993 • 6,011 citations

STATs and Gene Regulation

1997 • 3,927 citations

An Nrf2/Small Maf Heterodimer Mediates the Induction of Phase II Detoxifying Enzyme Genes through Antioxidant Response Elements

1997 • 3,743 citations

Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain

1999 • 3,344 citations

Protein Oxidation in Aging, Disease, and Oxidative Stress

1997 • 3,299 citations

Identification of a Novel Inhibitor of Mitogen-activated Protein Kinase Kinase

1998 • 3,026 citations

Prooxidant States and Tumor Promotion

1985 • 2,541 citations

Protein kinase C and lipid signaling for sustained cellular responses

1995 • 2,527 citations

SB 203580 is a specific inhibitor of a MAP kinase homologue which is stimulated by cellular stresses and interleukin‐1

1995 • 2,080 citations

Strategies of antioxidant defense

1993 • 1,963 citations

Protein Kinase C: Structure, Function, and Regulation

1995 • 1,640 citations

Isolation of NF-E2-related factor 2 (Nrf2), a NF-E2-like basic leucine zipper transcriptional activator that binds to the tandem NF-E2/AP1 repeat of the beta-globin locus control region.

1994 • 1,512 citations

Glutathione and glutathione-dependent enzymes represent a co-ordinately regulated defence against oxidative stress

1999 • 1,494 citations

The antioxidant responsive element. Activation by oxidative stress and identification of the DNA consensus sequence required for functional activity

1991 • 1,432 citations

Transcription Factor Nrf2 Coordinately Regulates a Group of Oxidative Stress-inducible Genes in Macrophages

2000 • 1,411 citations

The regulation of transcription by phosphorylation

1992 • 1,316 citations

Nrf2, a Cap'n'Collar Transcription Factor, Regulates Induction of the Heme Oxygenase-1 Gene

1999 • 1,233 citations

Activation of DNA-binding activity in an apparently cytoplasmic precursor of the NF-κB transcription factor

1988 • 1,200 citations

Oxidative stress and the molecular biology of antioxidant defenses.

1997 • 1,031 citations

Reactive oxygen species and programmed cell death

1996 • 745 citations

Erythroid transcription factor NF-E2 is a haematopoietic-specific basic–leucine zipper protein

1993 • 655 citations

Bach Proteins Belong to a Novel Family of BTB-Basic Leucine Zipper Transcription Factors That Interact with MafK and Regulate Transcription through the NF-E2 Site

1996 • 622 citations

Regulation of γ-Glutamylcysteine Synthetase Subunit Gene Expression by the Transcription Factor Nrf2

1999 • 584 citations

Transcriptional regulation of the rat glutathione S-transferase Ya subunit gene. Characterization of a xenobiotic-responsive element controlling inducible expression by phenolic antioxidants.

1990 • 522 citations

Transcriptional regulation of the rat NAD(P)H:quinone reductase gene

1991 • 499 citations

Xenobiotic-inducible expression of murine glutathione S-transferase Ya subunit gene is controlled by an electrophile-responsive element.

1990 • 472 citations

Regulation of transcription by dimerization of erythroid factor NF-E2 p45 with small Maf proteins

1994 • 434 citations

Signal transduction from the cell surface to the nucleus through the phosphorylation of transcription factors

1994 • 404 citations

Transcriptional Regulation of the Antioxidant Response Element

2000 • 364 citations

Regulation of human NAD(P)H:quinone oxidoreductase gene. Role of AP1 binding site contained within human antioxidant response element.

1992 • 353 citations

The Nrf2 transcription factor contributes both to the basal expression of glutathione S-transferases in mouse liver and to their induction by the chemopreventive synthetic antioxidants, butylated hydroxyanisole and ethoxyquin

2000 • 317 citations

Molecular Cloning and Functional Characterization of a New Cap'n' Collar Family Transcription Factor Nrf3

1999 • 290 citations

The world according to Maf

1997 • 285 citations

Role of a Mitogen-activated Protein Kinase Pathway in the Induction of Phase II Detoxifying Enzymes by Chemicals

1999 • 278 citations

Protein Kinase C δ Associates with and Phosphorylates Stat3 in an Interleukin-6-dependent Manner

1999 • 200 citations

Interaction between Protein Kinase C δ and the c-Abl Tyrosine Kinase in the Cellular Response to Oxidative Stress

2000 • 199 citations

p38 Mitogen-activated Protein Kinase Negatively Regulates the Induction of Phase II Drug-metabolizing Enzymes That Detoxify Carcinogens

2000 • 193 citations

Down regulation of phorbol diester receptors by proteolytic degradation of protein kinase C in a cultured cell line of fetal rat skin keratinocytes.

1986 • 183 citations

Transcriptional regulation of a rat liver glutathione S-transferase Ya subunit gene. Analysis of the antioxidant response element and its activation by the phorbol ester 12-O-tetradecanoylphorbol-13-acetate.

1994 • 152 citations

Antioxidant-induced Nuclear Translocation of CCAAT/Enhancer-binding Protein β

1997 • 133 citations

Isolation of cDNA encoding the human NF-E2 protein.

1993 • 126 citations

Tobacco smoke tumor promoters, catechol and hydroquinone, induce oxidative regulation of protein kinase C and influence invasion and metastasis of lung carcinoma cells.

1994 • 114 citations

Antioxidant-Inducible Genes

1996 • 111 citations

Transcriptional regulation of the rat NAD(P)H:quinone reductase gene. Characterization of a DNA-protein interaction at the antioxidant responsive element and induction by 12-O-tetradecanoylphorbol 13-acetate.

1993 • 100 citations

The role of protein kinase C in the regulation of cell growth and in signalling to the cell nucleus

2000 • 94 citations

Regulatory Mechanisms Involved in Activator‐Protein‐1 (AP‐1)‐Mediated Activation of Glutathione‐S‐Transferase Gene Expression by Chemical Agents

1997 • 45 citations