Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

A Laboratory manual

1989 • 6,833 citations

An Nrf2/Small Maf Heterodimer Mediates the Induction of Phase II Detoxifying Enzyme Genes through Antioxidant Response Elements

1997 • 3,743 citations

The Glut athione S-Transferase Supergene Family: Regulation of GST and the Contribution of the lsoenzymes to Cancer Chemoprotection and Drug Resistance Part I

1995 • 3,492 citations

Dietary Carcinogens and Anticarcinogens

1983 • 3,028 citations

pEF-BOS, a powerful mammalian expression vector

1990 • 1,641 citations

Isolation of NF-E2-related factor 2 (Nrf2), a NF-E2-like basic leucine zipper transcriptional activator that binds to the tandem NF-E2/AP1 repeat of the beta-globin locus control region.

1994 • 1,512 citations

Carcinogenesis by chemicals: an overview--G. H. A. Clowes memorial lecture.

1970 • 1,464 citations

The antioxidant responsive element. Activation by oxidative stress and identification of the DNA consensus sequence required for functional activity

1991 • 1,432 citations

Metabolic activation of benzo(a)pyrene proceeds by a diol-epoxide

1974 • 1,144 citations

The complete DNA sequence of vaccinia virus

1990 • 847 citations

The POZ domain: a conserved protein-protein interaction motif.

1994 • 770 citations

A new class of yeast transcriptional activators

1987 • 706 citations

Prediction of the Coding Sequences of Unidentified Human Genes. II. The Coding Sequences of 40 New Genes (KIAA0041-KIAA0080) Deduced by Analysis of cDNA Clones from Human Cell Line KG-1

1994 • 500 citations

Xenobiotic-inducible expression of murine glutathione S-transferase Ya subunit gene is controlled by an electrophile-responsive element.

1990 • 472 citations

Continuous tissue culture cell lines derived from chemically induced tumors of Japanese quail

1977 • 443 citations

Kelch encodes a component of intercellular bridges in Drosophila egg chambers

1993 • 436 citations

Regulation of transcription by dimerization of erythroid factor NF-E2 p45 with small Maf proteins

1994 • 434 citations

Chemical and molecular regulation of enzymes that detoxify carcinogens.

1993 • 426 citations

Cloning and Characterization of a Novel Erythroid Cell-Derived CNC Family Transcription Factor Heterodimerizing with the Small Maf Family Proteins

1995 • 423 citations

Maf nuclear oncoprotein recognizes sequences related to an AP-1 site and forms heterodimers with both Fos and Jun.

1994 • 418 citations

The BTB/POZ domain: a new protein-protein interaction motif common to DNA- and actin-binding proteins.

1995 • 393 citations

Hedgehog Elicits Signal Transduction by Means of a Large Complex Containing the Kinesin-Related Protein Costal2

1997 • 371 citations

Crystal Structure of a Free Radical Enzyme, Galactose Oxidase

1994 • 346 citations

Costal2, a Novel Kinesin-Related Protein in the Hedgehog Signaling Pathway

1997 • 329 citations

Developmental regulation of β-globin gene switching

1988 • 328 citations

Inhibitors of Chemical Carcinogenesis

1978 • 304 citations

The world according to Maf

1997 • 285 citations

The Maf transcription factors: regulators of differentiation

1997 • 272 citations

The electrophile counterattack response: Protection against neoplasia and toxicity

1993 • 260 citations

The maternal gene skn-1 encodes a protein that is distributed unequally in early C. elegans embryos

1993 • 251 citations

Identification of a Second Region Upstream of the Mouse Heme Oxygenase-1 Gene That Functions as a Basal Level and Inducer-dependent Transcription Enhancer

1995 • 219 citations

Pheromone Response in Yeast: Association of Bem1p with Proteins of the MAP Kinase Cascade and Actin

1995 • 209 citations

Induction of Phase I and Phase II Drug-Metabolizing Enzyme mRNA, Protein, and Activity by BHA, Ethoxyquin, and Oltipraz

1995 • 189 citations

Erythroblast cell lines transformed by a temperature-sensitive mutant of avian erythroblastosis virus: A model system to study erythroid differentiation in vitro

1982 • 188 citations

Drosophila kelch motif is derived from a common enzyme fold

1994 • 179 citations

Dietary Carcinogens and Anti-Carcinogens

1984 • 148 citations

Interactions between collagen-binding stress protein HSP47 and collagen. Analysis of kinetic parameters by surface plasmon resonance biosensor.

1994 • 142 citations

Induction of cystine and glutamate transport activity in human fibroblasts by diethyl maleate and other electrophilic agents.

1984 • 140 citations

Maf nuclear oncoprotein recognizes sequences related to an AP-1 site and forms heterodimers with both Fos and Jun

1994 • 133 citations

Prediction of the Coding Sequences of Unidentified Human Genes. IV. The Coding Sequences of 40 New Genes (KIAA0121-KIAA0160) Deduced by Analysis of cDNA Clones from Human Cell Line KG-1

1995 • 121 citations

Antioxidant-Inducible Genes

1996 • 111 citations

Human small Maf proteins form heterodimers with CNC family transcription factors and recognize the NF-E2 motif

1997 • 105 citations

ENC-1: A Novel MammalianKelch-Related Gene Specifically Expressed in the Nervous System Encodes an Actin-Binding Protein

1997 • 95 citations

cDNA Cloning of Murine Nrf 2 Gene, Coding for a p45 NF-E2-Related Transcription Factor

1995 • 66 citations