Transcriptional Regulation of the Antioxidant Response Element

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

1983 • 11,902 citations

An Nrf2/Small Maf Heterodimer Mediates the Induction of Phase II Detoxifying Enzyme Genes through Antioxidant Response Elements

1997 • 3,743 citations

Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain

1999 • 3,344 citations

Strategies of antioxidant defense

1993 • 1,963 citations

Redox Regulation of Fos and Jun DNA-Binding Activity in Vitro

1990 • 1,592 citations

Isolation of NF-E2-related factor 2 (Nrf2), a NF-E2-like basic leucine zipper transcriptional activator that binds to the tandem NF-E2/AP1 repeat of the beta-globin locus control region.

1994 • 1,512 citations

The antioxidant responsive element. Activation by oxidative stress and identification of the DNA consensus sequence required for functional activity

1991 • 1,432 citations

Nrf1 and Nrf2 positively and c-Fos and Fra1 negatively regulate the human antioxidant response element-mediated expression of NAD(P)H:quinone oxidoreductase ₁ gene

1996 • 1,027 citations

Functional antioxidant responsive elements

1997 • 702 citations

Rapid and preferential activation of the c-jun gene during the mammalian UV response.

1991 • 685 citations

Nrf2 and Nrf1 in association with Jun proteins regulate antioxidant response element-mediated expression and coordinated induction of genes encoding detoxifying enzymes

1998 • 553 citations

Transcriptional regulation of the rat glutathione S-transferase Ya subunit gene. Characterization of a xenobiotic-responsive element controlling inducible expression by phenolic antioxidants.

1990 • 522 citations

Transcriptional regulation of the rat NAD(P)H:quinone reductase gene

1991 • 499 citations

Xenobiotic-inducible expression of murine glutathione S-transferase Ya subunit gene is controlled by an electrophile-responsive element.

1990 • 472 citations

Regulation of transcription by dimerization of erythroid factor NF-E2 p45 with small Maf proteins

1994 • 434 citations

Regulation of human NAD(P)H:quinone oxidoreductase gene. Role of AP1 binding site contained within human antioxidant response element.

1992 • 353 citations

Role of a Mitogen-activated Protein Kinase Pathway in the Induction of Phase II Detoxifying Enzymes by Chemicals

1999 • 278 citations

An Electrophile Responsive Element (EpRE) Regulates β-Naphthoflavone Induction of the Human γ-Glutamylcysteine Synthetase Regulatory Subunit Gene

1998 • 260 citations

Electrophile and antioxidant regulation of enzymes that detoxify carcinogens.

1995 • 230 citations

Antitumor promotion by phenolic antioxidants: inhibition of AP-1 activity through induction of Fra expression.

1995 • 222 citations

MafB, a new Maf family transcription activator that can associate with Maf and Fos but not with Jun.

1994 • 219 citations

The Rat Quinone Reductase Antioxidant Response Element

1995 • 153 citations

Transcriptional regulation of a rat liver glutathione S-transferase Ya subunit gene. Analysis of the antioxidant response element and its activation by the phorbol ester 12-O-tetradecanoylphorbol-13-acetate.

1994 • 152 citations

hMAF, a Small Human Transcription Factor That Heterodimerizes Specifically with Nrf1 and Nrf2

1997 • 124 citations

Butylated Hydroxyanisole and Its Metabolitetert-Butylhydroquinone Differentially Regulate Mitogen-activated Protein Kinases

1997 • 115 citations

Human small Maf proteins form heterodimers with CNC family transcription factors and recognize the NF-E2 motif

1997 • 105 citations

Activity and Expression of Murine Small Maf Family Protein MafK

1995 • 100 citations

Regulation of rat glutathione S-transferase Ya subunit gene expression. DNA-protein interaction at the antioxidant responsive element.

1992 • 96 citations

Small Maf proteins interact with the human transcription factor TCF11/Nrf1/LCR-F1

1996 • 91 citations