Nuclear Factor κB Activity Is Essential for Matrix Metalloproteinase-1 and -3 Upregulation in Rabbit Dermal Fibroblasts

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Function and Activation of NF-kappaB in the Immune System

1994 • 4,698 citations

Phorbol ester-inducible genes contain a common cis element recognized by a TPA-modulated trans-acting factor

1987 • 3,057 citations

Matrix Metalloproteinases: A Review

1993 • 2,998 citations

IκB: a Specific Inhibitor of the NF-κB Transcription Factor

1988 • 2,203 citations

Structure, Regulation and Function of NF-kappaB

1994 • 2,110 citations

NF-κB: A lesson in family values

1995 • 1,266 citations

Activated transcription factor nuclear factor-kappa B is present in the atherosclerotic lesion.

1996 • 795 citations

Regulatory mechanism of 92 kDa type IV collagenase gene expression which is associated with invasiveness of tumor cells.

1993 • 704 citations

12-O-tetradecanoyl-phorbol-13-acetate induction of the human collagenase gene is mediated by an inducible enhancer element located in the 5'-flanking region.

1987 • 699 citations

Cytokine-stimulated human vascular smooth muscle cells synthesize a complement of enzymes required for extracellular matrix digestion.

1994 • 644 citations

Cross-coupling of the NF-kappa B p65 and Fos/Jun transcription factors produces potentiated biological function.

1993 • 639 citations

Functional and physical associations between NF-kappa B and C/EBP family members: a Rel domain-bZIP interaction.

1993 • 530 citations

The AP-1 site and MMP gene regulation: What is all the fuss about?

1997 • 507 citations

Synergistic upregulation of metalloproteinase‐9 by growth factors and inflammatory cytokines: an absolute requirement for transcription factor NF‐κB

1998 • 500 citations

The collagenase gene promoter contains a TPA and oncogene-responsive unit encompassing the PEA3 and AP-1 binding sites.

1990 • 450 citations

AP-1 and NF-kB Regulation in Rheumatoid Arthritis and Murine Collagen-Induced Arthritis

1998 • 367 citations

Nuclear factor–kB in rheumatoid synovium. Localization of P50 and P65

1995 • 289 citations

Enhanced Expression of Vascular Matrix Metalloproteinases Induced In Vitro by Cytokines and in Regions of Human Atherosclerotic Lesions^a

1994 • 272 citations

Divergent regulation by growth factors and cytokines of 95 kDa and 72 kDa gelatinases and tissue inhibitors or metalloproteinases-1, -2, and -3 in rabbit aortic smooth muscle cells

1996 • 253 citations

Inhibition of endothelial cell activation by adenovirus-mediated expression of I kappa B alpha, an inhibitor of the transcription factor NF-kappa B.

1996 • 252 citations

Constitutive and enhanced expression from the CMV major IE promoter in a defective adenovirus vector

1992 • 222 citations

Role of nuclear factor‐kappa B in atherogenesis

1997 • 176 citations

The AP-1 sequence is necessary but not sufficient for phorbol induction of collagenase in fibroblasts

1991 • 160 citations

Matrix Metalloproteinase Gene Expression^a

1994 • 156 citations

The rabbit gene for 92-kDa matrix metalloproteinase. Role of AP1 and AP2 in cell type-specific transcription.

1994 • 109 citations

Inhibition of proliferation, but not of Ca2+ mobilization, by cyclic AMP and GMP in rabbit aortic smooth-muscle cells

1992 • 108 citations

Serum-induced proliferation of rabbit aortic smooth muscle cells from the contractile state is inhibited by 8-Br-CAMP but not 8-Br-cGMP

1990 • 107 citations

Induction of collagenase and stromelysin gene expression by mechanical injury in a vascular smooth muscle‐derived cell line

1993 • 105 citations

Cloning of a complementary dna for rabbit proactivator. a metalloproteinase that activates synovial cell collagenase, shares homology with stromelysin and transin, and is coordinately regulated with collagenase

1987 • 86 citations

Induction of interleukin‐1 receptors on chondrocytes by fibroblast growth factor: A possible mechanism for modulation of interleukin‐1 activity

1989 • 74 citations

High DNA-binding activity of transcription factor NF-kappa B in synovial membranes of patients with rheumatoid arthritis.

1995 • 74 citations

Activation of the serum response factor by p65/NF-kappaB.

1996 • 66 citations

Reverse Transcription-Polymerase Chain Reaction Phenotyping of Metalloproteinases and Inhibitors Involved in Tumor Matrix Invasion

1993 • 47 citations

Differential regulation of metalloprotease steady‐state mRNA levels by IL‐1 and FGF in rabbit articular chondrocytes

1992 • 17 citations

Evidence that suppression of IL-1 induced collagenase mRNA expression by dihomo-γ-linolenic acid (DGLA) involves inhibition of NFκB binding

1997 • 8 citations