The collagenase gene promoter contains a TPA and oncogene-responsive unit encompassing the PEA3 and AP-1 binding sites.

Phorbol ester-inducible genes contain a common cis element recognized by a TPA-modulated trans-acting factor

1987 • 3,057 citations

Inducibility of κ immunoglobulin enhancer-binding protein NF-κB by a posttranslational mechanism

1986 • 2,043 citations

How eukaryotic transcriptional activators work

1988 • 1,924 citations

NF-κB: A pleiotropic mediator of inducible and tissue-specific gene control

1989 • 1,622 citations

The jun proto-oncogene is positively autoregulated by its product, Jun/AP-1

1988 • 1,256 citations

12-O-tetradecanoyl-phorbol-13-acetate induction of the human collagenase gene is mediated by an inducible enhancer element located in the 5'-flanking region.

1987 • 699 citations

Viral myb oncogene encodes a sequence-specific DNA-binding activity

1988 • 608 citations

Requirement for fos gene expression in the transcriptional activation of collagenase by other oncogenes and phorbol esters

1988 • 597 citations

The ability of a ternary complex to form over the serum response element correlates with serum inducibility of the human c-fos promoter

1989 • 495 citations

The v-myb oncogene product binds to and activates the promyelocyte-specific mim-1 gene

1989 • 460 citations

Calcium and growth factor pathways of c-fos transcriptional activation require distinct upstream regulatory sequences.

1988 • 404 citations

Identification and purification of a polypeptide that binds to the c-fos serum response element.

1987 • 398 citations

Modularity in promoters and enhancers

1989 • 366 citations

Transcriptional activation by the v-myb oncogene and its cellular progenitor, c-myb

1989 • 302 citations

The c-fos serum response element responds to protein kinase C-dependent and -independent signals but not to cyclic AMP.

1988 • 245 citations

Mutation of the c-fos gene dyad symmetry element inhibits serum inducibility of transcription in vivo and the nuclear regulatory factor binding in vitro.

1987 • 238 citations

Autoregulation of fos: the dyad symmetry element as the major target of repression.

1989 • 211 citations

PEA3 is a nuclear target for transcription activation by non-nuclear oncogenes.

1989 • 197 citations

Trans-repression of the mouse c-fos promoter: A novel mechanism of fos-mediated trans-regulation

1989 • 187 citations

A Harvey-ras responsive transcription element is also responsive to a tumour-promoter and to serum

1988 • 187 citations

Activation of the polyomavirus enhancer by a murine activator protein 1 (AP1) homolog and two contiguous proteins.

1988 • 186 citations

Repression of c-fos transcription is mediated through p67SRF bound to the SRE.

1989 • 182 citations

Isolation of human cDNA clones ofskiand the ski-related gene,sno

1989 • 169 citations

Transforming but not immortalizing oncogenes activate the transcription factor PEA1.

1988 • 160 citations

Two distinct cellular phosphoproteins bind to the c-fos serum response element.

1989 • 140 citations

Cross-Binding of Factors to Functionally Different Promoter Elements in c-fos and Skeletal Actin Genes

1989 • 135 citations

An initiation site of DNA replication with transcriptional enhancer activity present upstream of the c-myc gene.

1988 • 134 citations

The c-Ha-ras oncogene and a tumor promoter activate the polyoma virus enhancer

1987 • 129 citations

An AP1-binding site in the c-fos gene can mediate induction by epidermal growth factor and 12-O-tetradecanoyl phorbol-13-acetate.

1989 • 127 citations

Trans-activation by the c-mybproto-oncogene

1989 • 126 citations

DNA replication origin and transcriptional enhancer in c-myc gene share the c-myc protein binding sequences.

1989 • 106 citations

Definition of an Ets1 Protein Domain Required for Nuclear Localization in Cells and DNA-Binding Activity In Vitro

1989 • 98 citations

Point mutational analysis of the humanc-fosserum response factor binding site

1989 • 98 citations

Purification of intercalator-released p67, a polypeptide that interacts specifically with the c-fos serum response element

1987 • 92 citations

Calcium and Growth Factor Pathways of c-fos Transcriptional Activation Require Distinct Upstream Regulatory Sequences

1988 • 88 citations

‘Nuclear’ oncogenes convert extracellular stimuli into changes in the genetic program

1989 • 83 citations

Mutation of the c-fos Gene Dyad Symmetry Element Inhibits Serum Inducibility of Transcription In Vivo and the Nuclear Regulatory Factor Binding In Vitro

1987 • 72 citations

AP1, a composite transcription factor implictted in abnormal growth control

1989 • 36 citations

An AP1-Binding Site in the c-fos Gene Can Mediate Induction by Epidermal Growth Factor and 12-O-Tetradecanoyl Phorbol-13-Acetate

1989 • 22 citations