Role of lipoxygenase in xenobiotic oxidation: Parathion metabolism catalyzed by highly purified soybean lipoxygenase

A new and rapid colorimetric determination of acetylcholinesterase activity

1961 • 25,114 citations

Leukotrienes: Mediators of Immediate Hypersensitivity Reactions and Inflammation

1983 • 2,839 citations

Transformation of arachidonic acid and homo-gamma-linolenic acid by rabbit polymorphonuclear leukocytes. Monohydroxy acids from novel lipoxygenases

1976 • 638 citations

Prostaglandin H Synthase and Xenobiotic Oxidation

1990 • 276 citations

Preparation and purification of lipid hydroperoxides from arachidonic and γ‐linolenic acids

1976 • 216 citations

A lipoxygenase in rabbit reticulocytes which attacks phospholipids and intact mitochondria

1975 • 202 citations

Studies on the metabolism of diethyl 4-nitrophenyl phosphorothionate (parathion) in vitro

1967 • 173 citations

Singlet oxygen production by soybean lipoxygenase isozymes.

1986 • 132 citations

On the mechanism of the oxygenation of arachidonic acid by human platelet lipoxygenase

1980 • 128 citations

Microsomal metabolism of parathion

1967 • 111 citations

Activation and degradation of the phosphorothionate insecticides parathion and EPN by rat brain

1989 • 108 citations

Examination of the metabolism in vitro of parathion (diethyl p-nitrophenyl phosphorothionate) by rat lung and brain

1976 • 74 citations

Studies of the metabolism of parathion with an apparently homogeneous preparation of rabbit liver cytochrome P-450.

1976 • 73 citations

Organophosphate splitting serum enzymes in different mammals

1974 • 65 citations

Lipoxygenase Metabolism of Arachidonic Acid in Brain

1985 • 65 citations

Metabolism of insecticides by reductive systems

1980 • 64 citations

Mammalian lipoxygenases: Molecular and catalytic properties

1989 • 62 citations

Oxygen-18 studies on the chemical mechanisms of the mixed function oxidase catalyzed desulfuration and dearylation reactions of parathion.

1971 • 57 citations

Arachidonate 15-lipoxygenase from human eosinophil-enriched leukocytes: Partial purification and properties

1988 • 56 citations

Hydroperoxidase activity of lipoxygenase: Hydrogen peroxide-dependent oxidation of xenobiotics

1988 • 55 citations

A search for oxygen-centered free radicals in the lipoxygenase/linoleic acid system

1986 • 54 citations

Hepatic microsomal detoxification of the organophosphates paraoxon and chlorpyrifos oxon in the mouse.

1983 • 52 citations

Formation of arachidonate lipoxygenase metabolites by human fetal membranes, uterine decidua vera and placenta.

1982 • 50 citations

Arachidonic acid metabolism by isolated epidermal basal and differentiated keratinocytes from the hairless mouse

1986 • 49 citations

Epoxidation of 7,8-dihydroxy-7,8-dihydrobenzo[a]pyrene via a hydroperoxide-dependent mechanism catalyzed by lipoxygenases

1989 • 43 citations

Hydrogen peroxide: A potent activator of dioxygenase activity of soybean lipoxygenase

1990 • 39 citations

Lipoxygenase-catalyzed epoxidation of benzo(a)pyrene-7,8-dihydrodiol

1989 • 38 citations

Oxidation of pesticides by purified cytochrome P-450 isozymes from mouse liver

1985 • 33 citations

Lipoxygenases and hydroperoxy/hydroxy-eicosatetraenoic acid formation

1987 • 31 citations

Hydroperoxidase activity of lipoxygenase: a potential pathway for xenobiotic metabolism in the presence of linoleic acid.

1988 • 31 citations

Arachidonic Acid Metabolites in the Rat and Human Brain New Findings on the Metabolism of Prostaglandin D₂ and Lipoxygenase Productsa

1989 • 27 citations

Differential toxicities of insecticides and halogenated aromatics

1985 • 26 citations

Epoxidation of cholesterol by hepatic microsomal lipid hydroperoxides

1982 • 26 citations

Styrene oxidation to styrene oxide coupled with arachidonic acid oxidation by soybean lipoxygenase

1983 • 24 citations

Fatty acid induced drug and carcinogen metabolism in rat and human colonic mucosa: A possible link to the association of high dietary fat intake and colonic carcinogenesis

1980 • 20 citations

Aldrin epoxidation. Catalytic potential of lipoxygenase coupled with linoleic acid oxidation.

1991 • 20 citations

Differential effects of 15-HPETE on arachidonic acid metabolism in collagen-stimulated human platelets

1988 • 15 citations

Comparison of the metabolism of parathion by a rat liver reconstituted mixed-function oxidase enzyme system and by a system containing cumene hydroperoxide and purified rat liver cytochrome P-450.

1977 • 13 citations

Dioxygenase and peroxidase activities of soybean lipoxygenase: synergistic interaction between linoleic acid and hydrogen peroxide.

1989 • 13 citations

Interaction between .gamma.-hexachlorocyclohexane and the gastrointestinal microflora and their effect on the absorption, biotransformation, and excretion of parathion by the rat

1984 • 12 citations