Lipoxygenase: a new pathway for 2-aminofluorene bioactivation

Detection of carcinogens as mutagens in the Salmonella/microsome test: assay of 300 chemicals.

1975 • 3,362 citations

Leukotrienes: Mediators of Immediate Hypersensitivity Reactions and Inflammation

1983 • 2,839 citations

Leukotrienes and Lipoxins: Structures, Biosynthesis, and Biological Effects

1987 • 2,237 citations

Inorganic Biochemistry

1974 • 834 citations

A new method for the isolation of deoxyribonucleic acids: evidence on the nature of bonds between deoxyribonucleic acid and protein

1957 • 519 citations

N-hydroxy-2-acetylaminofluorene sulfotransferase: its probable role in carcinogenesis and in protein-(methion-S-yl) binding in rat liver.

1970 • 354 citations

Biochemical formation and pharmacological, toxicological, and pathological properties of hydroxylamines and hydroxamic acids.

1973 • 328 citations

N-Hydroxylation: A New Metabolic Reaction Observed in the Rat with the Carcinogen 2-Acetylaminofluorene

1960 • 311 citations

Cytochrome P-450- and flavin-containing monooxygenase-catalyzed formation of the carcinogen N-hydroxy-2-aminofluorene and its covalent binding to nuclear DNA.

1982 • 103 citations

Co-oxidation of benzidine by prostaglandin synthase and comparison with the action of horseradish peroxidase.

1983 • 96 citations

Lack of N-hydroxy-2-acetylaminofluorene sulfotransferase activity in the mammary gland and Zymbal's gland of the rat.

1971 • 84 citations

The neutrophil and leukotrienes--role in health and disease.

1990 • 84 citations

The oxidation of 2-aminofluorene by prostaglandin endoperoxide synthetase. Comparison with other peroxidases.

1983 • 77 citations

Chloroperoxidase-catalysed oxidation of 4-chloroaniline to 4-chloronitrosobenze

1978 • 58 citations

Hydroperoxidase activity of lipoxygenase: Hydrogen peroxide-dependent oxidation of xenobiotics

1988 • 55 citations

Soybean lipoxygenase-catalyzed oxidations by linoleic acid hydroperoxide: Different reducing substrates and dehydrogenation of phenidone and BW 755C

1988 • 51 citations

Epoxidation of 7,8-dihydroxy-7,8-dihydrobenzo[a]pyrene via a hydroperoxide-dependent mechanism catalyzed by lipoxygenases

1989 • 43 citations

Hydrogen peroxide: A potent activator of dioxygenase activity of soybean lipoxygenase

1990 • 39 citations

Lipoxygenase-catalyzed epoxidation of benzo(a)pyrene-7,8-dihydrodiol

1989 • 38 citations

Lipoxygenases and hydroperoxy/hydroxy-eicosatetraenoic acid formation

1987 • 31 citations

Hydroperoxidase activity of lipoxygenase: a potential pathway for xenobiotic metabolism in the presence of linoleic acid.

1988 • 31 citations

Peroxidase-like activity of lipoxygenases: different substrate specificity of potato 5-lipoxygenase and soybean 15-lipoxygenase and particular affinity of vitamin E derivatives for the 5-lipoxygenase

1991 • 25 citations

Role of lipoxygenase in xenobiotic oxidation: Parathion metabolism catalyzed by highly purified soybean lipoxygenase

1991 • 23 citations

Lipoxygenase: a new pathway for 2-aminofluorene bioactivation

1991 • 23 citations

Reducing substrate activity of some aromatic amines for prostaglandin H synthase

1987 • 20 citations

Aldrin epoxidation. Catalytic potential of lipoxygenase coupled with linoleic acid oxidation.

1991 • 20 citations

Dioxygenase and peroxidase activities of soybean lipoxygenase: synergistic interaction between linoleic acid and hydrogen peroxide.

1989 • 13 citations

Mutagenic response of mouse lymphoma cells after activation of benzidine and 2-aminofluorene with purified prostaglandin H synthase

1990 • 13 citations

The Role of Leukotrienes in Human Pathophysiologya

1988 • 10 citations