Epigenetic programming of differential gene expression in development and evolution

Gene Action in the X-chromosome of the Mouse (Mus musculus L.)

1961 • 3,881 citations

A gene from the region of the human X inactivation centre is expressed exclusively from the inactive X chromosome

1991 • 1,469 citations

Genomic imprinting in mammalian development: a parental tug-of-war

1991 • 1,178 citations

DNA METHYLATION AND GENE ACTIVITY

1983 • 1,115 citations

Temporal and regional changes in DNA methylation in the embryonic, extraembryonic and germ cell lineages during mouse embryo development

1987 • 1,088 citations

The Inheritance of Epigenetic Defects

1987 • 1,058 citations

Preferential inactivation of the paternally derived X chromosome in the extraembryonic membranes of the mouse

1975 • 783 citations

Developmental pattern of gene-specific DNA methylation in the mouse embryo and germ line.

1992 • 729 citations

Conservation of position and exclusive expression of mouse Xist from the inactive X chromosome

1991 • 617 citations

Maternal-specific methylation of the imprinted mouse Igf2r locus identifies the expressed locus as carrying the imprinting signal

1993 • 602 citations

DNA methylation affects the formation of active chromatin

1986 • 588 citations

Genomic imprinting in mammalian development: a parental tug-of-war

1991 • 539 citations

The rate of hydrolytic deamination of 5-methylcytosine in double-stranded DNA

1994 • 448 citations

A paternal–specific methylation imprint marks the alleles of the mouse H19 gene

1995 • 410 citations

Expression of Xist during mouse development suggests a role in the initiation of X chromosome inactivation

1993 • 369 citations

The somatic replication of DNA methylation

1981 • 368 citations

Methylation of the Hprt gene on the inactive X occurs after chromosome inactivation

1987 • 363 citations

Current Topics in DEVELOPMENTAL BIOLOGY

2023 • 351 citations

DNA methylation and genomic imprinting

1994 • 349 citations

The ontogeny of allele-specific methylation associated with imprinted genes in the mouse.

1993 • 345 citations

Preferential expression of the maternally derived X chromosome in the mouse yolk sac

1977 • 328 citations

THE CONTROLLING ELEMENT IN SEX CHROMOSOME BEHAVIOR IN SCIARA

1960 • 299 citations

Sequential X chromosome inactivation coupled with cellular differentiation in early mouse embryos

1979 • 284 citations

The inheritance of acquired epigenetic variations

1989 • 252 citations

Role of replication time in the control of tissue-specific gene expression.

1987 • 249 citations

Evidence that random and imprinted Xist expression is controlled by preemptive methylation

1994 • 247 citations

Parental-specific methylation of an imprinted transgene is established during gametogenesis and progressively changes during embryogenesis

1991 • 246 citations

Epigenetic control of transgene expression and imprinting by genotype-specific modifiers

1990 • 241 citations

Clonal inheritance of the pattern of DNA methylation in mouse cells.

1982 • 229 citations

Selective Silencing of Eukaryotic DNA

1975 • 224 citations

A strain-specific modifier on mouse chromosome 4 controls the methylation of independent transgene loci

1991 • 223 citations

Both X chromosomes function before visible X-chromosome inactivation in female mouse embryos

1978 • 219 citations

Maternal inhibition of hepatitis B surface antigen gene expression in transgenic mice correlates with de novo methylation

1987 • 202 citations

Use of a HpaII-polymerase chain reaction assay to study DNA methylation in the Pgk-1 CpG island of mouse embryos at the time of X-chromosome inactivation.

1990 • 183 citations

DNA methylation and chromatin structure: a view from below

1990 • 166 citations

Genomic imprinting — defusing the ovarian time bomb

1994 • 156 citations

Methylation of the mouse Xist gene in sperm and eggs correlates with imprinted Xist expression and paternal X–inactivation

1995 • 155 citations

The association of transcriptionally active genes with the nuclear matrix of the chicken oviduct

1983 • 145 citations

Expression of Xist in mouse germ cells correlates with X–chromosome inactivation

1992 • 143 citations

Expression of the X–inactivation–associated gene XIST during spermatogenesis

1992 • 140 citations

Genomic imprinting.

1988 • 132 citations

Epigenetics and Evolution

2014 • 131 citations

HGPRT activity changes in preimplantation mouse embryos

1978 • 128 citations

Gametic imprinting in maize in relation to the angiosperm life cycle

1990 • 126 citations

Epigenetic and genetic factors affect transgene methylation imprinting

1989 • 123 citations

Gamete–specific methylation correlates with imprinting of the murine Xist gene

1995 • 113 citations

Preferential paternal X inactivation in extraembryonic tissues of early mouse embryos

1982 • 109 citations

Methylation and the X chromosome

1986 • 103 citations

Chapter 2 Biochemistry of Male Germ Cell Differentiation in Mammals: RNA Synthesis in Meiotic and Postmeiotic Cells

1978 • 101 citations

Homology-dependent gene silencing in transgenic plants: what does it really tell us?

1995 • 97 citations

Decrease in DNA methylase activity during preimplantation development in the mouse

1991 • 94 citations

Methylation of CpG sites of two X–linked genes coincides with X–inactivation in the female mouse embryo but not in the germ line

1992 • 90 citations

Cellular mosaicism in the methylation and expression of hemizygous loci in the mouse.

1989 • 84 citations

Variation in epigenetic inheritance

1990 • 73 citations

Aberrant Gene Expression during the Development of Hybrid Sunfishes (Perciformes, Teleostei)

1977 • 69 citations

X-chromosome activity in preimplantation mouse embryos from XX and XO mothers

1978 • 62 citations

A Stem-line Model for Cellular and Chromosomal Differentiation in Early Mouse Development

1981 • 61 citations

X-chromosome activity in female mouse embryos heterozygous forPgk-1and Searle's translocation, T(X; 16) 16H

1983 • 59 citations

Experimental embryological analysis of genetic imprinting in mouse development

1994 • 43 citations