Epigenetic control of transgene expression and imprinting by genotype-specific modifiers

The Inheritance of Epigenetic Defects

1987 • 1,058 citations

Identification of a nonhistone chromosomal protein associated with heterochromatin in Drosophila melanogaster and its gene.

1986 • 618 citations

Assembly and propagation of repressed and derepressed chromosomal states

1985 • 518 citations

Genomic imprinting determines methylation of parental alleles in transgenic mice

1987 • 480 citations

Parental legacy determines methylation and expression of an autosomal transgene: A molecular mechanism for parental imprinting

1987 • 478 citations

DIFFERENTIAL IMPRINTING AND EXPRESSION OF MATERNAL AND PATERNAL GENOMES

1988 • 451 citations

Degree of methylation of transgenes is dependent on gamete of origin

1987 • 407 citations

THE EVOLUTION OF DOMINANCE

1931 • 406 citations

Methylation of the Hprt gene on the inactive X occurs after chromosome inactivation

1987 • 363 citations

Epigenetic inheritance of transcriptional states in S. cerevisiae

1989 • 327 citations

The surface windfield over the Antarctic ice sheets

1987 • 324 citations

Dosage-dependent modifiers of position effect variegation in Drosophila and a mass action model that explains their effect.

1988 • 320 citations

Development of Gynogenetic Eggs in the Mouse: Implications for Parthenogenetic Embryos

1983 • 303 citations

Transgenes as probes for active chromosomal domains in mouse development

1988 • 251 citations

Mammalian X-Chromosome Action: Inactivation Limited in Spread and in Region of Origin

1963 • 247 citations

Retroviruses as probes for mammalian development: Allocation of cells to the somatic and germ cell lineages

1986 • 213 citations

A transgene containing lacZ inserted into the dystonia locus is expressed in neural tube

1988 • 208 citations

Molecular mechanisms in the developmental regulation of the maize Suppressor-mutator transposable element.

1988 • 207 citations

Maternal inhibition of hepatitis B surface antigen gene expression in transgenic mice correlates with de novo methylation

1987 • 202 citations

Conversion of Normal Behavior to Shiverer by Myelin Basic Protein Antisense cDNA in Transgenic Mice

1988 • 182 citations

Genomic imprinting and genetic disorders in man

1989 • 176 citations

Parental origin effects in mice

1986 • 175 citations

Transgenic mice containing intestinal fatty acid-binding protein-human growth hormone fusion genes exhibit correct regional and cell-specific expression of the reporter gene in their small intestine.

1988 • 174 citations

DNA methylation stabilizes X chromosome inactivation in eutherians but not in marsupials: evidence for multistep maintenance of mammalian X dosage compensation.

1987 • 171 citations

Anticipation in Huntington's disease is inherited through the male line but may originate in the female.

1988 • 171 citations

[45] Production of transgenic mice

1993 • 161 citations

Mechanisms underlying generation of gradients in gene expression within the intestine: an analysis using transgenic mice containing fatty acid binding protein-human growth hormone fusion genes.

1988 • 161 citations

Unmethylated CpG islands associated with genes in higher plant DNA

1988 • 146 citations

Origin of cells giving rise to mesoderm and endoderm in chick embryo

1990 • 146 citations

Mammalian Development: A Practical Approach

1988 • 140 citations

The relative importance of principal and modifying genes in determining some human diseases

1941 • 134 citations

Genomic imprinting.

1988 • 132 citations

Epigenetic and genetic factors affect transgene methylation imprinting

1989 • 123 citations

Transgenes as molecular probes for genomic imprinting

1988 • 108 citations

Cellular mosaicism in the methylation and expression of hemizygous loci in the mouse.

1989 • 84 citations

Developmental consequences of imprinting of parental chromosomes by DNA methylation

1990 • 80 citations

Huntington's Disease: Two Families with Differing Clinical Features Show Linkage to the G8 Probe

1985 • 75 citations

The inheritance and expression of disorganization, an unusual mutation in the mouse

1958 • 71 citations

Genome Imprinting and Dominance Modification

1989 • 63 citations

PARENTAL CONTROL OF POSITION-EFFECT VARIEGATION. II. EFFECT OF SEX OF PARENT CONTRIBUTING WHITE-MOTTLED REARRANGEMENT IN DROSOPHILA MELANOGASTER

1961 • 38 citations

A Methylation Mosaic Model for Mammalian Genome Imprinting

1989 • 32 citations