Use of a HpaII-polymerase chain reaction assay to study DNA methylation in the Pgk-1 CpG island of mouse embryos at the time of X-chromosome inactivation.

DNA Methylation and Gene Function

1980 • 2,069 citations

Temporal and regional changes in DNA methylation in the embryonic, extraembryonic and germ cell lineages during mouse embryo development

1987 • 1,088 citations

MAMMALIAN X-CHROMOSOME INACTIVATION

1983 • 635 citations

Methylation of the Hprt gene on the inactive X occurs after chromosome inactivation

1987 • 363 citations

A rapid method for the purification of DNA from blood

1987 • 323 citations

Sequential X chromosome inactivation coupled with cellular differentiation in early mouse embryos

1979 • 284 citations

Differences in DNA methylation during oogenesis and spermatogenesis and their persistence during early embryogenesis in the mouse.

1987 • 278 citations

Measurement by quantitative PCR of changes in HPRT, PGK-1, PGK-2, APRT, MTase, and Zfy gene transcripts during mouse spermatogenesis

1990 • 231 citations

MECHANISMS OF X-CHROMOSOME REGULATION

1988 • 222 citations

A quantitative Hpall-PCR assay to measure methylation of DNA from a small number of cells

1990 • 167 citations

Active X chromosome DNA is unmethylated at eight CCGG sites clustered in a guanine-plus-cytosine-rich island at the 5' end of the gene for phosphoglycerate kinase.

1986 • 164 citations

Chromosome Mapping and Expression of a Putative Testis-Determining Gene in Mouse

1989 • 146 citations

Mammalian Development: A Practical Approach

1988 • 140 citations

Mammalian development: A practical approach

1988 • 127 citations

Methylation patterns of repetitive DNA sequences in germ cells ofMus muscutus

1984 • 126 citations

Differences in the DNA of the inactive X chromosomes of fetal and extraembryonic tissues of mice

1983 • 123 citations

Methylation and the X chromosome

1986 • 103 citations

Demethylation of specific sites in the 5' region of the inactive X-linked human phosphoglycerate kinase gene correlates with the appearance of nuclease sensitivity and gene expression.

1988 • 90 citations

X-chromosome activity in female mouse embryos heterozygous forPgk-1and Searle's translocation, T(X; 16) 16H

1983 • 59 citations

Controlling elements in the mouse: V. Linkage tests with X-linked genes

1981 • 54 citations

DNA methylation and cell memory

1989 • 50 citations

Demethylation of Specific Sites in the 5′ Region of the Inactive X-Linked Human Phosphoglycerate Kinase Gene Correlates with the Appearance of Nuclease Sensitivity and Gene Expression

1988 • 33 citations

Reactivation ofhprt on the inactive X chromosome with DNA demethylating agents

1989 • 11 citations