Ephrin-B Reverse Signaling Is Mediated by a Novel PDZ-RGS Protein and Selectively Inhibits G Protein–Coupled Chemoattraction

Functional rafts in cell membranes

1997 • 9,471 citations

Green Fluorescent Protein as a Marker for Gene Expression

1994 • 6,572 citations

Function of the chemokine receptor CXCR4 in haematopoiesis and in cerebellar development

1998 • 2,496 citations

Impaired B-lymphopoiesis, myelopoiesis, and derailed cerebellar neuron migration in CXCR4- and SDF-1-deficient mice

1998 • 1,687 citations

Molecular Distinction and Angiogenic Interaction between Embryonic Arteries and Veins Revealed by ephrin-B2 and Its Receptor Eph-B4

1998 • 1,663 citations

Recognition of Unique Carboxyl-Terminal Motifs by Distinct PDZ Domains

1997 • 1,371 citations

THE EPHRINS AND EPH RECEPTORS IN NEURAL DEVELOPMENT

1998 • 1,082 citations

Roles of ephrinB ligands and EphB receptors in cardiovascular development: demarcation of arterial/venous domains, vascular morphogenesis, and sprouting angiogenesis

1999 • 1,019 citations

A Cell's Sense of Direction

1999 • 884 citations

p115 RhoGEF, a GTPase Activating Protein for Gα ₁₂ and Gα ₁₃

1998 • 834 citations

CENTRAL NERVOUS SYSTEM NEURONAL MIGRATION

1999 • 808 citations

Direct Stimulation of the Guanine Nucleotide Exchange Activity of p115 RhoGEF by Gα ₁₃

1998 • 765 citations

Transmembrane form of the kit ligand growth factor is determined by alternative splicing and is missing in the SId mutant

1991 • 740 citations

Ligands for EPH-Related Receptor Tyrosine Kinases that Require Membrane Attachment or Clustering for Activity

1994 • 720 citations

Symmetrical Mutant Phenotypes of the Receptor EphB4 and Its Specific Transmembrane Ligand ephrin-B2 in Cardiovascular Development

1999 • 708 citations

MEMBRANE-ANCHORED GROWTH FACTORS

1993 • 676 citations

Principles of neural cell migration

1990 • 659 citations

Identification of a New Family of Tissue-Specific Basic Helix-Loop-Helix Proteins with a Two-Hybrid System

1995 • 655 citations

Xenopus embryos regulate the nuclear localization of XMyoD.

1994 • 648 citations

cAMP-induced switching in turning direction of nerve growth cones

1997 • 614 citations

Neuronal regulation of astroglial morphology and proliferation in vitro.

1985 • 605 citations

Nuk Controls Pathfinding of Commissural Axons in the Mammalian Central Nervous System

1996 • 536 citations

Bidirectional signalling through the EPH-family receptor Nuk and its transmembrane ligands

1996 • 526 citations

PDZ domains in synapse assembly and signalling

2000 • 525 citations

Embryonic Expression and Function of the Chemokine SDF-1 and Its Receptor, CXCR4

1999 • 476 citations

PDZ Proteins Organize Synaptic Signaling Pathways

1998 • 474 citations

Inhibition of G-protein-mediated MAP kinase activation by a new mammalian gene family

1996 • 470 citations

Eph receptors and ephrins restrict cell intermingling and communication

1999 • 469 citations

PDZ Proteins Bind, Cluster, and Synaptically Colocalize with Eph Receptors and Their Ephrin Ligands

1998 • 455 citations

Eph receptors and ephrins: effectors of morphogenesis

1999 • 445 citations

Abnormal Cerebellar Development and Foliation in BDNF−/− Mice Reveals a Role for Neurotrophins in CNS Patterning

1997 • 432 citations

In vivo cell sorting in complementary segmental domains mediated by Eph receptors and ephrins

1999 • 431 citations

Tyrosine Phosphorylation of Transmembrane Ligands for Eph Receptors

1997 • 394 citations

Ligand-Gated Ion Channel Interactions with Cytoskeletal and Signaling Proteins

2000 • 352 citations

EphrinB Ligands Recruit GRIP Family PDZ Adaptor Proteins into Raft Membrane Microdomains

1999 • 345 citations

Molecular basis of semaphorin-mediated axon guidance

2000 • 300 citations

Compartmentalized signaling by GPI-anchored ephrin-A5 requires the Fyn tyrosine kinase to regulate cellular adhesion

1999 • 294 citations

The G-Protein Linked Receptor Facts Book

1994 • 292 citations

Cloning and Characterization of Neuropilin-1-Interacting Protein: A PSD-95/Dlg/ZO-1 Domain-Containing Protein That Interacts with the Cytoplasmic Domain of Neuropilin-1

1999 • 282 citations

The Carboxyl Terminus of B Class Ephrins Constitutes a PDZ Domain Binding Motif

1999 • 244 citations

GIPC, a PDZ domain containing protein, interacts specifically with the C terminus of RGS-GAIP

1998 • 222 citations

Netrin-1-mediated axon outgrowth and cAMP production requires interaction with adenosine A2b receptor

2000 • 216 citations

RGS proteins: more than just GAPs for heterotrimeric G proteins

1999 • 200 citations

The Eph family in retinal axon guidance

1997 • 187 citations

Antagonism between Goalpha and Gqalpha in Caenorhabditis elegans: the RGS protein EAT-16 is necessary for Goalpha signaling and regulates Gqalpha activity

1999 • 187 citations

The G-protein linked receptor facts book

1994 • 181 citations

Heterotrimeric G Protein Signaling: Roles in Immune Function and Fine-Tuning by RGS Proteins

1998 • 178 citations

An ephrin-A-dependent Signaling Pathway Controls Integrin Function and Is Linked to the Tyrosine Phosphorylation of a 120-kDa Protein

2001 • 175 citations

Eph receptors and ephrins

2002 • 166 citations

ELF-2, a New Member of the Eph Ligand Family, Is Segmentally Expressed in Mouse Embryos in the Region of the Hindbrain and Newly Forming Somites

1995 • 155 citations

Ephrins and their Eph receptors: multitalented directors of embryonic development

1999 • 148 citations

SIGNAL TRANSDUCTION IN THE CAENORHABDITIS ELEGANS NERVOUS SYSTEM

1998 • 143 citations

Divergence of RGS proteins: evidence for the existence of six mammalian RGS subfamilies

1999 • 137 citations

The Role of Chemokines in Regulating Cell Migration during Humoral Immune Responses

1999 • 133 citations

Pertussis Toxin-Sensitive Signal Controls the Trafficking of Thymocytes Across the Corticomedullary Junction in the Thymus

1999 • 123 citations

A PDZ Protein Regulates the Distribution of the Transmembrane Semaphorin, M-SemF

1999 • 113 citations

Eph Receptors and Ephrins in the Developing Chick Cerebellum: Relationship to Sagittal Patterning and Granule Cell Migration

2000 • 111 citations

Molecular cloning of a ligand for the EPH-related receptor protein-tyrosine kinase Htk.

1995 • 101 citations

Lifetime Regulation of G Protein–Effector Complex: Emerging Importance of RGS Proteins

1998 • 99 citations

Loss of cell adhesion in Xenopus laevis embryos mediated by the cytoplasmic domain of XLerk, an erythropoietin-producing hepatocellular ligand

1998 • 81 citations

Epidermal growth factor: Is the precursor a receptor?

1985 • 81 citations

Ephrin-B3, a ligand for the receptor EphB3, expressed at the midline of the developing neural tube

1998 • 76 citations

Two murine homologues of the human chemokine receptor CXCR4 mediating stromal cell‐derived factor 1α activation of G_i2 are differentially expressed in vivo

1997 • 75 citations

Cloning, characterization, and differential expression of MDK2 and MDK5, two novel receptor tyrosine kinases of the eck/eph family.

1995 • 57 citations

G Proteins and Axon Growth

1998 • 7 citations

Pertussis toxin-sensitive signal controls the trafficking of′ thymocytes across the corticomedullary junction in the′ thymus.

1999 • 6 citations