PDZ domains in synapse assembly and signalling

Cloned Glutamate Receptors

1994 • 3,989 citations

Domain Interaction Between NMDA Receptor Subunits and the Postsynaptic Density Protein PSD-95

1995 • 1,861 citations

Driving AMPA Receptors into Synapses by LTP and CaMKII: Requirement for GluR1 and PDZ Domain Interaction

2000 • 1,507 citations

Recognition of Unique Carboxyl-Terminal Motifs by Distinct PDZ Domains

1997 • 1,371 citations

Rapid Spine Delivery and Redistribution of AMPA Receptors After Synaptic NMDA Receptor Activation

1999 • 1,272 citations

The rat brain postsynaptic density fraction contains a homolog of the drosophila discs-large tumor suppressor protein

1992 • 1,180 citations

Enhanced long-term potentiation and impaired learning in mice with mutant postsynaptic density-95 protein

1998 • 1,147 citations

Crystal Structures of a Complexed and Peptide-Free Membrane Protein–Binding Domain: Molecular Basis of Peptide Recognition by PDZ

1996 • 1,127 citations

Coupling of mGluR/Homer and PSD-95 Complexes by the Shank Family of Postsynaptic Density Proteins

1999 • 1,024 citations

Clustering of Shaker-type K+ channels by interaction with a family of membrane-associated guanylate kinases

1995 • 994 citations

Shank, a Novel Family of Postsynaptic Density Proteins that Binds to the NMDA Receptor/PSD-95/GKAP Complex and Cortactin

1999 • 980 citations

GRIP: a synaptic PDZ domain-containing protein that interacts with AMPA receptors

1997 • 866 citations

Synaptic structure and development: The neuromuscular junction

1993 • 846 citations

Activity-Dependent Modulation of Synaptic AMPA Receptor Accumulation

1998 • 693 citations

Role of AMPA Receptor Cycling in Synaptic Transmission and Plasticity

1999 • 690 citations

A kinase-regulated PDZ-domain interaction controls endocytic sorting of the β2-adrenergic receptor

1999 • 673 citations

SynGAP: a Synaptic RasGAP that Associates with the PSD-95/SAP90 Protein Family

1998 • 617 citations

The β2-adrenergic receptor interacts with the Na+/H+-exchanger regulatory factor to control Na+/H+ exchange

1998 • 582 citations

A Synaptic Ras-GTPase Activating Protein (p135 SynGAP) Inhibited by CaM Kinase II

1998 • 578 citations

A Tripartite Protein Complex with the Potential to Couple Synaptic Vesicle Exocytosis to Cell Adhesion in Brain

1998 • 548 citations

NSF Binding to GluR2 Regulates Synaptic Transmission

1998 • 542 citations

Clustering of AMPA Receptors by the Synaptic PDZ Domain–Containing Protein PICK1

1999 • 540 citations

Heteromultimerization and NMDA Receptor-Clustering Activity of Chapsyn-110, a Member of the PSD-95 Family of Proteins

1996 • 539 citations

A Developmental Change in NMDA Receptor-Associated Proteins at Hippocampal Synapses

2000 • 521 citations

PDZ Proteins Organize Synaptic Signaling Pathways

1998 • 474 citations

Importance of the Intracellular Domain of NR2 Subunits for NMDA Receptor Function In Vivo

1998 • 465 citations

Rapid redistribution of glutamate receptors contributes to long-term depression in hippocampal cultures

1999 • 462 citations

PDZ Proteins Bind, Cluster, and Synaptically Colocalize with Eph Receptors and Their Ephrin Ligands

1998 • 455 citations

SAP102, a Novel Postsynaptic Protein That Interacts with NMDA Receptor Complexes In Vivo

1996 • 422 citations

SAP97 Is Associated with the α-Amino-3-hydroxy-5-methylisoxazole-4-propionic Acid Receptor GluR1 Subunit

1998 • 415 citations

SAP90, a rat presynaptic protein related to the product of the Drosophila tumor suppressor gene dlg-A.

1993 • 415 citations

Regulation of morphological postsynaptic silent synapses in developing hippocampal neurons

1999 • 399 citations

Interaction of the N-Ethylmaleimide–Sensitive Factor with AMPA Receptors

1998 • 396 citations

Heterogeneity in the Molecular Composition of Excitatory Postsynaptic Sites during Development of Hippocampal Neurons in Culture

1998 • 396 citations

Molecular characterization and spatial distribution of SAP97, a novel presynaptic protein homologous to SAP90 and the Drosophila discs-large tumor suppressor protein

1995 • 388 citations

The AMPA Receptor GluR2 C Terminus Can Mediate a Reversible, ATP-Dependent Interaction with NSF and α- and β-SNAPs

1998 • 355 citations

Novel Anchorage of GluR2/3 to the Postsynaptic Density by the AMPA Receptor–Binding Protein ABP

1998 • 354 citations

EphrinB Ligands Recruit GRIP Family PDZ Adaptor Proteins into Raft Membrane Microdomains

1999 • 345 citations

Synaptic Targeting of the Postsynaptic Density Protein PSD-95 Mediated by Lipid and Protein Motifs

1999 • 327 citations

Crystal structure of a PDZ domain

1996 • 315 citations

Mints, Munc18-interacting Proteins in Synaptic Vesicle Exocytosis

1997 • 308 citations

CRIPT, a Novel Postsynaptic Protein that Binds to the Third PDZ Domain of PSD-95/SAP90

1998 • 304 citations

N-Terminal Palmitoylation of PSD-95 Regulates Association with Cell Membranes and Interaction with K+ Channel Kv1.4

1998 • 292 citations

A Novel Multiple PDZ Domain-containing Molecule Interacting withN-Methyl-d-aspartateReceptors and Neuronal Cell Adhesion Proteins

1998 • 290 citations

Hippocampal LTD Expression Involves a Pool of AMPARs Regulated by the NSF–GluR2 Interaction

1999 • 290 citations

LIN-10 Is a Shared Component of the Polarized Protein Localization Pathways in Neurons and Epithelia

1998 • 271 citations

Essential Role fordlgin Synaptic Clustering of Shaker K⁺ChannelsIn Vivo

1997 • 262 citations

Ca2+-Dependent Routes to Ras: Mechanisms for Neuronal Survival, Differentiation, and Plasticity?

1996 • 262 citations

SAP90 Binds and Clusters Kainate Receptors Causing Incomplete Desensitization

1998 • 261 citations

Regulation of the TRP Ca2+ Channel by INAD in Drosophila Photoreceptors

1996 • 256 citations

PDZ domains bind carboxy-terminal sequences of target proteins

1996 • 244 citations

Proline-Rich Synapse-Associated Protein-1/Cortactin Binding Protein 1 (ProSAP1/CortBP1) Is a PDZ-Domain Protein Highly Enriched in the Postsynaptic Density

1999 • 243 citations

Molecular determinants of presynaptic active zones

2000 • 213 citations

Synaptic Clustering of the Cell Adhesion Molecule Fasciclin II by Discs-Large and its Role in the Regulation of Presynaptic Structure

1997 • 208 citations

Disulfide-Linked Head-to-Head Multimerization in the Mechanism of Ion Channel Clustering by PSD-95

1997 • 207 citations

Proline-Rich Synapse-Associated Proteins ProSAP1 and ProSAP2 Interact with Synaptic Proteins of the SAPAP/GKAP Family

1999 • 192 citations

AMPA receptor–PDZ interactions in facilitation of spinal sensory synapses

1999 • 190 citations

Citron Binds to PSD-95 at Glutamatergic Synapses on Inhibitory Neurons in the Hippocampus

1999 • 186 citations

Crystal structure of the hCASK PDZ domain reveals the structural basis of class II PDZ domain target recognition

1998 • 179 citations

The Making of Neurexins

1998 • 155 citations

PDZ-mediated interactions retain the epithelial GABA transporter on the basolateral surface of polarized epithelial cells

1999 • 155 citations

GRASP-1

2000 • 153 citations

Role of the Carboxy-Terminal Region of the GluRε2 Subunit in Synaptic Localization of the NMDA Receptor Channel

1998 • 133 citations

Organization and regulation of proteins at synapses

1999 • 130 citations

Kalirin, a Cytosolic Protein with Spectrin-like and GDP/GTP Exchange Factor-like Domains That Interacts with Peptidylglycine α-Amidating Monooxygenase, an Integral Membrane Peptide-processing Enzyme

1997 • 121 citations

E-cadherin mediated cell adhesion recruits SAP97 into the cortical cytoskeleton

1998 • 114 citations

Synapse maturation and structural plasticity at Drosophila neuromuscular junctions

1996 • 113 citations

Citron, a Rho-Target, Interacts with PSD-95/SAP-90 at Glutamatergic Synapses in the Thalamus

1999 • 98 citations

Functional expression of rat synapse-associated proteins SAP97 and SAP102 in Drosophila dlg-1 mutants: effects on tumor suppression and synaptic bouton structure

1997 • 96 citations

SAP Family Proteins

2000 • 92 citations

Synaptic PDZ domain-containing proteins

1998 • 79 citations

Cyclic Peptides as Non-carboxyl-terminal Ligands of Syntrophin PDZ Domains

1998 • 71 citations

Synaptic proteins and the assembly of synaptic junctions

1996 • 69 citations

Sorting out Genes that Regulate Epithelial and Neuronal Polarity

1998 • 60 citations

Functional analysis of the guanylate kinase‐like domain in the synapse‐associated protein SAP97

1998 • 53 citations