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Brain-derived neurotrophic factor rescues and prevents chronic intermittent hypoxia-induced impairment of hippocampal long-term synaptic plasticity

Data up to Jan 2025

Published2010
Citations93
References45

Total Citations Per Year

Abstract

References (45)

Obstructive Sleep Apnea as a Risk Factor for Stroke and Death

2005 • 2,843 citations

Physiology of the Neurotrophins

1996 • 1,908 citations

Long-Term Potentiation and Memory

2004 • 1,888 citations

Neurotrophins as synaptic modulators

2001 • 1,773 citations

Public Information: From Nosy Neighbors to Cultural Evolution

2004 • 1,434 citations

Epidemiology of Pediatric Obstructive Sleep Apnea

2008 • 1,256 citations

Cleavage of proBDNF by tPA/Plasmin Is Essential for Long-Term Hippocampal Plasticity

2004 • 1,084 citations

Neurotrophins: key regulators of cell fate and cell shape in the vertebrate nervous system

2000 • 1,053 citations

The changing scene of neurotrophic factors

1991 • 827 citations

BDNF: A key regulator for protein synthesis-dependent LTP and long-term memory?

2007 • 734 citations

Behavioral and Anatomical Correlates of Chronic Episodic Hypoxia during Sleep in the Rat

2001 • 544 citations

Gender differences in sleep disordered breathing in a community-based sample.

1994 • 503 citations

Increased oxidative stress is associated with chronic intermittent hypoxia-mediated brain cortical neuronal cell apoptosis in a mouse model of sleep apnea

2004 • 360 citations

Long-term Intermittent Hypoxia in Mice: Protracted Hypersomnolence with Oxidative Injury to Sleep-Wake Brain Regions

2004 • 323 citations

Pathophysiology of obstructive sleep apnoea

1995 • 318 citations

A new planar multielectrode array for extracellular recording: application to hippocampal acute slice

1999 • 311 citations

Intermittent Hypoxia Is Associated with Oxidative Stress and Spatial Learning Deficits in the Rat

2003 • 300 citations

Up-regulating BDNF with an ampakine rescues synaptic plasticity and memory in Huntington's disease knockin mice

2009 • 249 citations

Impaired Spatial Learning and Hyperactivity in Developing Rats Exposed to Intermittent Hypoxia

2002 • 226 citations

Epidemiology of Obstructive Sleep Apnea Syndrome

1992 • 206 citations

Hippocampal synaptic plasticity and spatial learning are impaired in a rat model of sleep fragmentation

2006 • 202 citations

Suppression of hippocampal plasticity‐related gene expression by sleep deprivation in rats

2006 • 189 citations

Cyclooxygenase 2 and Intermittent Hypoxia-induced Spatial Deficits in the Rat

2003 • 137 citations

Inducible Nitric Oxide Synthase in Long-term Intermittent Hypoxia

2005 • 131 citations

Obstructive Sleep Apnea in Children: Implications for the Developing Central Nervous System

2008 • 131 citations

Hippocampal neurogenesis is reduced by sleep fragmentation in the adult rat

2007 • 127 citations

Neurotrophins induce release of neurotrophins by the regulated secretory pathway

1998 • 124 citations

Intermittent Hypoxia during Development Induces Long-Term Alterations in Spatial Working Memory, Monoamines, and Dendritic Branching in Rat Frontal Cortex

2005 • 122 citations

From modulator to mediator: rapid effects of BDNF on ion channels

2004 • 121 citations

Nitric oxide synthase and intermittent hypoxia-induced spatial learning deficits in the rat

2004 • 115 citations

Increased susceptibility to intermittent hypoxia in aging rats: changes in proteasomal activity, neuronal apoptosis and spatial function

2003 • 114 citations

Intermittent hypoxia causes REM sleep deficits and decreases EEG delta power in NREM sleep in the C57BL/6J mouse

2005 • 111 citations

Effects of obstructive sleep apnea on cognitive function: A comparison between younger and older OSAS patients

2007 • 108 citations

Acute and long-term synaptic modulation by neurotrophins

2004 • 101 citations

Pathophysiology of Obstructive Sleep Apnea

2008 • 100 citations

Intermittent hypoxic exposure during light phase induces changes in cAMP response element binding protein activity in the rat CA1 hippocampal region: water maze performance correlates

2003 • 91 citations

Apolipoprotein E-Deficient Mice Exhibit Increased Vulnerability to Intermittent Hypoxia-Induced Spatial Learning Deficits

2005 • 87 citations

Temporal aspects of spatial task performance during intermittent hypoxia in the rat: evidence for neurogenesis

2003 • 83 citations

Effect of intermittent hypoxia on long-term potentiation in rat hippocampal slices

2004 • 77 citations

Spatial learning and memory deficits following exposure to 24 h of sleep fragmentation or intermittent hypoxia in a rat model of obstructive sleep apnea

2009 • 67 citations

Intermittent hypoxia induces time-dependent changes in the protein kinase B signaling pathway in the hippocampal CA1 region of the rat

2003 • 49 citations

Apnea promotes glutamate-induced excitotoxicity in hippocampal neurons

2007 • 49 citations

Treatment options for obstructive sleep apnea

2009 • 37 citations

Long‐Term Recording of LTP in Cultured Hippocampal Slices

2002 • 33 citations

Deleted Work

1955 • 0 citations

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