Mitogen-activated Protein Kinase Phosphorylates and Regulates the HIV-1 Vif Protein

Specificity of receptor tyrosine kinase signaling: Transient versus sustained extracellular signal-regulated kinase activation

1995 • 4,589 citations

The MAPK signaling cascade

1995 • 3,300 citations

The mitogen-activated protein kinase signal transduction pathway

1993 • 2,174 citations

An inducible transcription factor activates expression of human immunodeficiency virus in T cells

1987 • 2,149 citations

How MAP Kinases Are Regulated

1995 • 1,742 citations

HIV-1 entry into quiescent primary lymphocytes: Molecular analysis reveals a labile, latent viral structure

1990 • 1,560 citations

Transformation of Mammalian Cells by Constitutively Active MAP Kinase Kinase

1994 • 1,370 citations

Signal transduction via the MAP kinases: proceed at your own RSK.

1993 • 1,262 citations

Cyclin D1 Expression Is Regulated Positively by the p42/p44 and Negatively by the p38/HOG Pathway

1996 • 1,203 citations

Mitogen-activated protein kinases p42mapk and p44mapk are required for fibroblast proliferation.

1993 • 992 citations

HIV F/3' orf encodes a phosphorylated GTP-binding protein resembling an oncogene product

1987 • 523 citations

The HIV A (sor) gene product is essential for virus infectivity

1987 • 475 citations

A sensitive method for detection of calmodulin-dependent protein kinase II activity in sodium dodecyl sulfate-polyacrylamide gel

1989 • 466 citations

Vif is crucial for human immunodeficiency virus type 1 proviral DNA synthesis in infected cells

1993 • 449 citations

Role of vif in replication of human immunodeficiency virus type 1 in CD4+ T lymphocytes

1992 • 447 citations

Identification of substrate recognition determinants for human ERK1 and ERK2 protein kinases.

1991 • 446 citations

Mitogen-activated protein kinases: versatile transducers for cell signaling

1992 • 439 citations

Definition of a consensus sequence for peptide substrate recognition by p44mpk, the meiosis-activated myelin basic protein kinase

1991 • 407 citations

The sor Gene of HIV-1 Is Required for Efficient Virus Transmission in Vitro

1987 • 365 citations

HIV-1 infection of nondividing cells: C-terminal tyrosine phosphorylation of the viral matrix protein is a key regulator

1995 • 309 citations

Protein Phosphorylation; A Practical Approach

1994 • 273 citations

Construction andIn VitroProperties of SIV_macMutants with Deletions in "Nonessential" Genes

1994 • 261 citations

Megakaryocytic Differentiation Induced by Constitutive Activation of Mitogen-Activated Protein Kinase Kinase

1997 • 237 citations

Activation of mitogen-activated protein kinases by vascular endothelial growth factor and basic fibroblast growth factor in capillary endothelial cells is inhibited by the antiangiogenic factor 16-kDa N-terminal fragment of prolactin.

1995 • 231 citations

Human immunodeficiency virus type 1 Nef associateswith a cellular serine kinase in T lymphocytes.

1994 • 227 citations

Biochemical and immunological analysis of human immunodeficiency virus gag gene products p17 and p24

1988 • 203 citations

Differential activities of the human immunodeficiency virus type 1-encoded Vpu protein are regulated by phosphorylation and occur in different cellular compartments

1994 • 201 citations

The human immunodeficiency virus type 1 Vif protein modulates the postpenetration stability of viral nucleoprotein complexes

1996 • 189 citations

Cell-dependent requirement of human immunodeficiency virus type 1 Vif protein for maturation of virus particles

1993 • 188 citations

Efficiency of viral DNA synthesis during infection of permissive and nonpermissive cells with vif-negative human immunodeficiency virus type 1

1993 • 177 citations

Physical and Functional Interaction of Nef with Lck

1996 • 165 citations

Phosphorylation of PHAS-I by mitogen-activated protein (MAP) kinase. Identification of a site phosphorylated by MAP kinase in vitro and in response to insulin in rat adipocytes.

1994 • 165 citations

Phosphorylation-dependent human immunodeficiency virus type 1 infection and nuclear targeting of viral DNA.

1996 • 154 citations

Cytoskeleton association and virion incorporation of the human immunodeficiency virus type 1 Vif protein

1996 • 153 citations

The Vif and Gag proteins of human immunodeficiency virus type 1 colocalize in infected human T cells

1997 • 147 citations

Human immunodeficiency virus type 1 Nef binds directly to Lck and mitogen-activated protein kinase, inhibiting kinase activity

1996 • 134 citations

Specific Interaction of the Human Immunodeficiency Virus Tat Proteins with a Cellular Protein Kinase

1993 • 132 citations

The Vif protein of human and simian immunodeficiency viruses is packaged into virions and associates with viral core structures

1995 • 128 citations

Role of Vif in human immunodeficiency virus type 1 reverse transcription

1996 • 121 citations

Peripheral blood mononuclear cells produce normal amounts of defective Vif- human immunodeficiency virus type 1 particles which are restricted for the preretrotranscription steps

1995 • 120 citations

Human immunodeficiency virus type 1 Vif does not influence expression or virion incorporation of gag-, pol-, and env-encoded proteins

1996 • 116 citations

Role of vif during Packing of the Core of HIV-1

1994 • 110 citations

Phosphorylation of Vif and Its Role in HIV-1 Replication

1996 • 107 citations

The Critical Role of p38 MAP Kinase in T Cell HIV-1 Replication

1997 • 107 citations

Activation of the HIV-1 Long Terminal Repeat by Cytokines and Environmental Stress Requires an Active CSBP/p38 MAP Kinase

1996 • 103 citations

Characterization of human immunodeficiency virus type 1 Vif particle incorporation

1996 • 101 citations

Human immunodeficiency virus type 1 Vif protein binds to the Pr55Gag precursor

1997 • 99 citations

Phosphorylation of the rev gene product of human immunodeficiency virus type 1

1988 • 88 citations

Cell cycle reentry of mammalian fibroblasts is accompanied by the sustained activation of P44^mapk and P42^mapk isoforms in the G1 phase and their inactivation at the G1/s transition

1995 • 85 citations

Viral latency in HIV disease

1995 • 74 citations

Biological activity of human immunodeficiency virus type 1 Vif requires membrane targeting by C-terminal basic domains

1995 • 68 citations

Association of ERK2 mitogen-activated protein kinase with human immunodeficiency virus particles

1997 • 62 citations

The human immunodeficiency virus rev protein is a nuclear phosphoprotein

1989 • 61 citations

Phenotypically Vif- human immunodeficiency virus type 1 is produced by chronically infected restrictive cells

1997 • 53 citations

In vitro binding and phosphorylation of human immunodeficiency virus type 1 Nef protein by serine/threonine protein kinase

1995 • 48 citations

The Ras-Raf pathway is activated in human immunodeficiency virus-infected monocytes and particpates in the activation of NF-kappa B

1996 • 45 citations

Phosphorylation of HIV-1 gag proteins by protein kinase C.

1993 • 38 citations

Functional significance of phosphorylation to the human immunodeficiency virus Rev protein

1989 • 36 citations

Induction of phosphorylation of human immunodeficiency virus type 1 Nef and enhancement of CD4 downregulation by phorbol myristate acetate

1997 • 33 citations

Regulation of Human Immunodeficiency Virus Nef Protein by Phosphorylation

1994 • 30 citations