Differential activities of the human immunodeficiency virus type 1-encoded Vpu protein are regulated by phosphorylation and occur in different cellular compartments

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues

2013 • 47,043 citations

Tricine-sodium dodecyl sulfate-polyacrylamide gel electrophoresis for the separation of proteins in the range from 1 to 100 kDa

1987 • 11,491 citations

A new technique for the assay of infectivity of human adenovirus 5 DNA

1973 • 9,740 citations

Production of acquired immunodeficiency syndrome-associated retrovirus in human and nonhuman cells transfected with an infectious molecular clone

1986 • 2,918 citations

The Rous sarcoma virus long terminal repeat is a strong promoter when introduced into a variety of eukaryotic cells by DNA-mediated transfection.

1982 • 1,371 citations

Influenza virus M2 protein has ion channel activity

1992 • 1,205 citations

Tumor necrosis factor and interleukin-1 lead to phosphorylation and loss of I kappa B alpha: a mechanism for NF-kappa B activation.

1993 • 1,047 citations

Casein kinase 2: An ‘eminence grise’ in cellular regulation?

1990 • 920 citations

Human immunodeficiency virus type 1 Vpu protein induces rapid degradation of CD4

1992 • 553 citations

soluble form of CD4 (T4) protein inhibits AIDS virus infection

1988 • 530 citations

HIV F/3' orf encodes a phosphorylated GTP-binding protein resembling an oncogene product

1987 • 523 citations

The human immunodeficiency virus type 1-specific protein vpu is required for efficient virus maturation and release

1990 • 461 citations

A Novel Gene of HIV-1, vpu , and Its 16-Kilodalton Product

1988 • 445 citations

Biosynthesis, cleavage, and degradation of the human immunodeficiency virus 1 envelope glycoprotein gp160.

1988 • 442 citations

Genetic organization of a chimpanzee lentivirus related to HIV-1

1990 • 418 citations

Trans-activation of the human immunodeficiency virus long terminal repeat sequence by DNA viruses.

1986 • 368 citations

Isolation, sequencing, and disruption of the yeast CKA2 gene: casein kinase II is essential for viability in Saccharomyces cerevisiae.

1990 • 365 citations

Characterization of a continuous T-cell line susceptible to the cytopathic effects of the acquired immunodeficiency syndrome (AIDS)-associated retrovirus.

1985 • 337 citations

The gag gene products of human immunodeficiency virus type 1: alignment within the gag open reading frame, identification of posttranslational modifications, and evidence for alternative gag precursors

1988 • 310 citations

Dephosphorylation and activation of Xenopusp34cdc2 protein kinase during the cell cycle

1989 • 300 citations

Identification of a protein encoded by the vpu gene of HIV-1

1988 • 295 citations

Casein kinase type II is involved in the inhibition by 5,6-dichloro-1-beta-D-ribofuranosylbenzimidazole of specific RNA polymerase II transcription.

1986 • 285 citations

Functional role of human immunodeficiency virus type 1 vpu.

1989 • 280 citations

Molecular and biochemical analyses of human immunodeficiency virus type 1 vpu protein

1989 • 267 citations

Human immunodeficiency virus type 1 Vpu protein regulates the formation of intracellular gp160-CD4 complexes

1992 • 251 citations

Tumor Necrosis Factor and Interleukin-1 Lead to Phosphorylation and Loss of IκBα: a Mechanism for NF-κB Activation

1993 • 223 citations

Human immunodeficiency virus type 1 Vpu protein is an oligomeric type I integral membrane protein

1993 • 218 citations

Casein kinase II is elevated in solid human tumours and rapidly proliferating non‐neoplastic tissue

1990 • 211 citations

Vpu protein of human immunodeficiency virus type 1 enhances the release of capsids produced by gag gene constructs of widely divergent retroviruses.

1993 • 189 citations

The Human Immunodeficiency Virus Type 1 Encoded Vpu Protein is Phosphorylated by Casein Kinase-2 (CK-2) at Positions Ser52 and Ser56 within a Predicted α-Helix-Turn-α-Helix-Motif

1994 • 148 citations

Phosphorylation by cellular casein kinase II is essential for transcriptional activity of vesicular stomatitis virus phosphoprotein P.

1992 • 138 citations

Human immunodeficiency virus type 1 Vpu protein induces degradation of CD4 in vitro: the cytoplasmic domain of CD4 contributes to Vpu sensitivity

1993 • 134 citations

Structural features of the cytoplasmic region of CD4 required for internalization.

1990 • 111 citations

Human‐immundeficiency‐virus‐type‐1‐encoded Vpu protein is phosphorylated by casein kinase II

1992 • 104 citations

Phosphorylation of the rev gene product of human immunodeficiency virus type 1

1988 • 88 citations

Isolation, Sequencing, and Disruption of the Yeast CKA2 Gene: Casein Kinase II Is Essential for Viability in Saccharomyces cerevisiae

1990 • 79 citations

Envelope glycoprotein and CD4 independence of vpu-facilitated human immunodeficiency virus type 1 capsid export

1992 • 78 citations

Human immunodeficiency virus type 1 has an additional coding sequence in the central region of the genome.

1988 • 71 citations

The human immunodeficiency virus rev protein is a nuclear phosphoprotein

1989 • 61 citations

Amino acid similarity coefficients for protein modeling and sequence alignment derived from main-chain folding angles

1991 • 53 citations

Sequences present in the cytoplasmic domain of CD4 are necessary and sufficient to confer sensitivity to the human immunodeficiency virus type 1 Vpu protein

1994 • 50 citations

Regulation of nicotinic acetylcholine receptors by protein phosphorylation

1988 • 49 citations

The phosphorylation of eukaryotic initiation factor 2: A principle of translational control in mammalian cells

1989 • 38 citations

Brefeldin A Inhibits the Processing and Secretion of Envelope Glycoproteins of Human Immunodeficiency Virus Type 1

1991 • 38 citations

Synthesis and characterization of the hydrophilic C-terminal domain of the human immunodeficiency virus type 1-encoded virus protein U (Vpu).

1993 • 23 citations

Poliovirus-associated protein kinase: destabilization of the virus capsid and stimulation of the phosphorylation reaction by Zn2+

1989 • 22 citations

The Antibody Response to the HIV-1 Specific "Out" (vpu) Protein: Identification of an Immunodominant Epitope and Correlation of Antibody Detectability to Clinical Stages

1990 • 20 citations

Expression ofnef, vpu, CA and CD4 during the infection of lymphoid and monocytic cell lines with HIV-1

1992 • 11 citations