Distribution and possible roles of the highly polysialylated neural cell adhesion molecule (NCAM-H) in the developing and adult central nervous system

Autoradiographic and histological studies of postnatal neurogenesis. IV. Cell proliferation and migration in the anterior forebrain, with special reference to persisting neurogenesis in the olfactory bulb

1969 • 1,471 citations

Neurogenesis in the Adult Rat: Electron Microscopic Analysis of Light Radioautographs

1977 • 1,438 citations

Neural Cell Adhesion Molecule: Structure, Immunoglobulin-Like Domains, Cell Surface Modulation, and Alternative RNA Splicing

1987 • 1,134 citations

Origin of luteinizing hormone-releasing hormone neurons

1989 • 1,098 citations

Activity-dependent neuronal plasticity following tissue injury and inflammation

1992 • 933 citations

Contact and adhesive specificities in the associations, migrations, and targeting of cells and axons

1992 • 895 citations

Migration and distribution of two populations of hippocampal granule cell precursors during the perinatal and postnatal periods

1990 • 805 citations

The Neural Cell Adhesion Molecule (NCAM) as a Regulator of Cell-Cell Interactions

1988 • 790 citations

Brainstem projections of sensory and motor components of the vagus nerve in the rat

1982 • 741 citations

Spatial regulation of axonal glycoprotein expression on subsets of embryonic spinal neurons

1988 • 739 citations

Neural cell adhesion molecules and myelin-associated glycoprotein share a common carbohydrate moiety recognized by monoclonal antibodies L2 and HNK-1

1984 • 723 citations

CELL ADHESION MOLECULES: Implications for a Molecular Histology

1991 • 707 citations

Synaptic reorganization by mossy fibers in human epileptic fascia dentata

1991 • 666 citations

Developmental Neurobiology

1991 • 659 citations

Kinetics of homophilic binding by embryonic and adult forms of the neural cell adhesion molecule.

1983 • 635 citations

Antennapedia homeobox peptide regulates neural morphogenesis.

1991 • 616 citations

Neurons in the Rat Dentate Gyrus Granular Layer Substantially Increase During Juvenile and Adult Life

1982 • 589 citations

Differential inhibition of neurone–neurone, neurone–astrocyte and astrocyte–astrocyte adhesion by L1, L2 and N-CAM antibodies

1985 • 497 citations

Highly polysialylated neural cell adhesion molecule (NCAM-H) is expressed by newly generated granule cells in the dentate gyrus of the adult rat

1993 • 465 citations

An L1-like molecule, the 8D9 antigen, is a potent substrate for neurite extension.

1987 • 464 citations

Chemical characterization of a neural cell adhesion molecule purified from embryonic brain membranes.

1982 • 445 citations

Cell adhesion molecules in early chicken embryogenesis.

1982 • 420 citations

Occurrence of α2–8 linked polysialosyl units in a neural cell adhesion molecule

1983 • 408 citations

Morphoregulatory activities of NCAM and N-cadherin can be accounted for by G protein-dependent activation of L- and N-type neuronal Ca2+ channels

1991 • 394 citations

NZB mouse system for production of monoclonal antibodies to weak bacterial antigens: isolation of an IgG antibody to the polysaccharide capsules of Escherichia coli K1 and group B meningococci.

1985 • 389 citations

Neural cell adhesion molecules influence second messenger systems

1989 • 387 citations

Guidance of optic axons in vivo by a preformed adhesive pathway on neuroepithelial endfeet

1984 • 386 citations

Cell adhesion molecules in vertebrate neural development.

1988 • 386 citations

Modulation of an NCAM-Related Adhesion Molecule with Long-Term Synaptic Plasticity in Aplysia

1992 • 377 citations

Analysis of neurogenesis in a mammalian neuroepithelium: Proliferation and differentiation of an olfactory neuron precursor in vitro

1989 • 365 citations

Polysialylation: from bacteria to brains

1992 • 351 citations

The effects of cAMP on differentiation of cultured Schwann cells: progression from an early phenotype (04+) to a myelin phenotype (P0+, GFAP-, N-CAM-, NGF-receptor-) depends on growth inhibition.

1991 • 350 citations

Adult and embryonic mouse neural cell adhesion molecules have different binding properties

1983 • 350 citations

Olfactory Recognition: A Simple Memory System

1990 • 349 citations

A year in the life of the immunoglobulin superfamily

1987 • 345 citations

The distribution of nine peptides in rat spinal cord with special emphasis on the substantia gelatinosa and on the area around the central canal (laminaX)

1981 • 342 citations

Brief seizure episodes induce long-term potentiation and mossy fibre sprouting in the hippocampus

1990 • 332 citations

An IgG monoclonal antibody to group B meningococci cross-reacts with developmentally regulated polysialic acid units of glycoproteins in neural and extraneural tissues.

1987 • 328 citations

N-cadherin, NCAM, and integrins promote retinal neurite outgrowth on astrocytes in vitro.

1988 • 326 citations

Occurrence of unique polysialosyl carbohydrate units in glycoproteins of developing brain.

1982 • 324 citations

Altered expression of neuronal cell adhesion molecules induced by nerve injury and repair.

1986 • 319 citations

Polysialic acid as a regulator of intramuscular nerve branching during embryonic development

1990 • 319 citations

NCAM polysialic acid can regulate both cell-cell and cell-substrate interactions.

1991 • 317 citations

A monoclonal antibody against meningococcus group B polysaccharides distinguishes embryonic from adult N-CAM.

1986 • 314 citations

Serotonin-Mediated Endocytosis of apCAM: an Early Step of Learning-Related Synaptic Growth in Aplysia

1992 • 313 citations

Differences in the carbohydrate structures of neural cell-adhesion molecules from adult and embryonic chicken brains.

1982 • 311 citations

Mapping of the distribution of polysialylated neural cell adhesion molecule throughout the central nervous system of the adult rat: An immunohistochemical study

1992 • 309 citations

Distribution of N-CAM in synaptic and extrasynaptic portions of developing and adult skeletal muscle.

1986 • 307 citations

The neural cell adhesion molecule N-CAM enhances L1-dependent cell-cell interactions.

1990 • 305 citations

The 180-kD component of the neural cell adhesion molecule N-CAM is involved in cell-cell contacts and cytoskeleton-membrane interactions

1987 • 303 citations

Extension of neurites on axons is impaired by antibodies against specific neural cell surface glycoproteins.

1987 • 303 citations

Alterations in neural cell adhesion molecules during development of different regions of the nervous system

1984 • 302 citations

Maturation of astrocytes in vitro alters the extent and molecular basis of neurite outgrowth

1990 • 299 citations

Neurite outgrowth in response to transfected N-CAM changes during development and is modulated by polysialic acid

1990 • 299 citations

Studies of adhesion molecules mediating interactions between cells of peripheral nervous system indicate a major role for L1 in mediating sensory neuron growth on Schwann cells in culture.

1988 • 288 citations

Birth of Projection Neurons in Adult Avian Brain May Be Related to Perceptual or Motor Learning

1990 • 283 citations

Specific alteration of NCAM-mediated cell adhesion by an endoneuraminidase.

1985 • 278 citations

Embryonic to adult conversion of neural cell adhesion molecules in normal and staggerer mice.

1982 • 275 citations

Neuronal cell–cell adhesion depends on interactions of N-CAM with heparin-like molecules

1986 • 270 citations

Sequential expression and differential function of multiple adhesion molecules during the formation of cerebellar cortical layers.

1987 • 266 citations

Differentiation state-dependent surface mobilities of two forms of the neural cell adhesion molecule

1986 • 262 citations

A threshold effect of the major isoforms of NCAM on neurite outgrowth

1990 • 260 citations

Expression of highly polysialylated NCAM in the neocortex and piriform cortex of the developing and the adult rat

1991 • 257 citations

Expression of cell adhesion molecules in the olfactory system of the adult mouse: Presence of the embryonic form of N-CAM

1988 • 250 citations

Retention of embryonic features by an adult neuronal system capable of plasticity: polysialylated neural cell adhesion molecule in the hypothalamo-neurohypophysial system.

1991 • 243 citations

Prenatal development of GABA‐ergic neurons in the neocortex of the rat

1989 • 237 citations

Neurite outgrowth on muscle cell surfaces involves extracellular matrix receptors as well as Ca2+-dependent and -independent cell adhesion molecules.

1987 • 233 citations

Phosphatidylinositol is involved in the membrane attachment of NCAM-120, the smallest component of the neural cell adhesion molecule.

1986 • 232 citations

Polysialic acid influences specific pathfinding by avian motoneurons

1992 • 229 citations

Polysialic acid is associated with sodium channels and the neural cell adhesion molecule N-CAM in adult rat brain.

1992 • 224 citations

Human muscle neural cell adhesion molecule (N-CAM): Identification of a muscle-specific sequence in the extracellular domain

1987 • 221 citations

Molecular topography of the neural cell adhesion molecule N-CAM: surface orientation and location of sialic acid-rich and binding regions.

1983 • 217 citations

Immunoelectron microscopic localization of the neural cell adhesion molecules L1 and N-CAM during postnatal development of the mouse cerebellum.

1987 • 215 citations

Cell adhesion molecules as targets for Hox genes: neural cell adhesion molecule promoter activity is modulated by cotransfection with Hox-2.5 and -2.4.

1992 • 215 citations

Binding properties of a cell adhesion molecule from neural tissue.

1982 • 214 citations

An EM analysis of the synaptic connections of horseradish peroxidase‐filled stalked cells and islet cells in the substantia gelatinosa of adult cat spinal cord

1980 • 210 citations

Neural cell adhesion molecules modulate tyrosine phosphorylation of tubulin in nerve growth cone membranes

1992 • 197 citations

Differential exon usage involving an unusual splicing mechanism generates at least eight types of NCAM cDNA in mouse brain.

1989 • 196 citations

Selective expression of the 180-kD component of the neural cell adhesion molecule N-CAM during development.

1985 • 196 citations

Immunoelectron‐microscopic localization of the 180 kD component of the neural cell adhesion molecule N‐CAM in postsynaptic membranes

1989 • 195 citations

The persistent expression of a highly polysialylated NCAM in the dentate gyrus of the adult rat

1991 • 188 citations

Reexpression of poly(sialic acid) units of the neural cell adhesion molecule in Wilms tumor.

1988 • 187 citations

Use of prokaryotic-derived probes to identify poly(sialic acid) in neonatal neuronal membranes.

1984 • 183 citations

Learning and memory

1977 • 183 citations

Golgi studies on the development of granule cells of the rat olfactory bulb with reference to migration in the subependymal layer

1987 • 182 citations

Intercellular space is affected by the polysialic acid content of NCAM.

1992 • 179 citations

Differential distribution of cell adhesion molecules during histogenesis of the chick nervous system

1986 • 179 citations

Functional cooperation between the neural adhesion molecules L1 and N-CAM is carbohydrate dependent.

1990 • 174 citations

Development and differentiation of early generated cells of sublayer VIb in the somatosensory cortex of the rat: A correlated Golgi and autoradiographic study

1989 • 170 citations

Tissue- and developmental stage-specific forms of a neural cell surface antigen linked to differences in glycosylation of a common polypeptide.

1982 • 167 citations

Expression of L1 and N-CAM cell adhesion molecules during development of the mouse olfactory system

1989 • 167 citations

The embryonic form of neural cell surface molecule (E-NCAM) in the rat hippocampus and its reexpression on glial cells following kainic acid- induced status epilepticus

1992 • 165 citations

Occurrence of Sialic Acids in Drosophila melanogaster

1992 • 164 citations

Regulation of axonal growth in the vertebrate nervous system by interactions between glycoproteins belonging to two subgroups of the immunoglobulin superfamily.

1992 • 161 citations

Studies on the transmembrane disposition of the neural cell adhesion molecule N-CAM. A monoclonal antibody recognizing a cytoplasmic domain and evidence for the presence of phosphoserine residues

1984 • 158 citations

Neurobiology of Glycoconjugates

1989 • 155 citations

NCAM: Structural diversity, function and regulation of expression

1992 • 152 citations

Monoclonal antibody against cell surface glycoprotein of neurons

1981 • 151 citations

Identification of a heparin binding domain of the neural cell adhesion molecule N-CAM using synthetic peptides

1989 • 151 citations

Neuropeptides in long ascending spinal tract cells in the rat: Evidence for parallel processing of ascending information

1988 • 149 citations

Rapid transneuronal degeneration and death of cortical neurons following removal of the olfactory bulb in adult rats

1978 • 147 citations

Immunocytochemical demonstration of neural cell adhesion molecule (NCAM) along the migration route of luteinizing hormone‐releasing hormone (LHRH) neurons in mice

1992 • 146 citations

Identification of a peptide sequence involved in homophilic binding in the neural cell adhesion molecule NCAM.

1992 • 145 citations

The VASE exon downregulates the neurite growth-promoting activity of NCAM 140

1992 • 145 citations

Evidence that late-generated granule cells do not simply replace earlier formed neurons in the rat dentate gyrus

1986 • 144 citations

Developmental control of N-CAM sialylation state by Golgi sialyltransferase isoforms

1988 • 144 citations

Hippocampal NCAM180 transiently increases sialylation during the acquisition and consolidation of a passive avoidance response in the adult rat

1992 • 143 citations

The ontogeny of luteinizing hormone-releasing hormone (LHRH) producing neurons in the chick embryo: possible evidence for migrating LHRH neurons from the olfactory epithelium expressing a highly polysialylated neural cell adhesion molecule

1991 • 140 citations

Nerve growth factor enhances expression of neuron-glia cell adhesion molecule in PC12 cells.

1986 • 139 citations

alpha-2,8-Polysialic acid is the neuronal surface receptor of antennapedia homeobox peptide.

1991 • 137 citations

The origin of the luteinizing hormone-releasing hormone (LHRH) neurons in newts (Cynops pyrrhogaster): the effect of olfactory placode ablation

1992 • 136 citations

Cellular expression of liver and neural cell adhesion molecules after transfection with their cDNAs results in specific cell-cell binding.

1987 • 136 citations

Isolation of a novel glycoprotein from the eggs of rainbow trout: Occurrence of disialosyl groups on all carbohydrate chains

1978 • 134 citations

Structure of the piriform cortex of the opossum. I. Description of neuron types with golgi methods

1983 • 131 citations

Cell Adhesion Molecules in Neural Development (Part 1 of 2)

1989 • 131 citations

Changes in neural cell adhesion molecule (NCAM) structure during vertebrate neural development.

1987 • 129 citations

Astrocyte-derived TGF-beta 2 and NGF differentially regulate neural recognition molecule expression by cultured astrocytes.

1991 • 123 citations

Topological distribution of different forms of neural cell adhesion molecule in the developing chick visual system

1984 • 123 citations

Polysialic acid is required for optimal growth of axons on a neuronal substrate

1992 • 121 citations

Neural cell adhesion molecules in rodent brains isolated by monoclonal antibodies with cross-species reactivity.

1982 • 119 citations

Polypeptide variation in an N-CAM extracellular immunoglobulin-like fold is developmentally regulated through alternative splicing

1988 • 117 citations

Different extracellular domains of the neural cell adhesion molecule (N-CAM) are involved in different functions.

1992 • 117 citations

Alteration of the retinotectal map in Xenopus by antibodies to neural cell adhesion molecules.

1984 • 117 citations

Multiple oligosaccharide chains in the voltage-sensitive Na channel from Electrophorus electricus: Evidence for α-2,8-linked polysialic acid

1987 • 111 citations

Expression of the unique NCAM VASE exon is independently regulated in distinct tissues during development.

1990 • 110 citations

Immunocytological localization of cell adhesion molecules L1 and N-CAM and the shared carbohydrate epitope L2 during development of the mouse neocortex

1986 • 106 citations

Antibodies to the L1 adhesion molecule inhibit Schwann cell ensheathment of neurons in vitro.

1989 • 103 citations

Learning and memory

1991 • 101 citations

Polysialic acid units are spatially and temporally expressed in developing postnatal rat kidney.

1987 • 101 citations

Expression of the neural cell adhesion molecule NCAM in endocrine cells.

1989 • 99 citations

Developmental expression of neural cell adhesion molecules in the mouse neocortex and olfactory bulb

1991 • 98 citations

Retention of J1/tenascin and the polysialylated form of the neural cell adhesion molecule (N-CAM) in the adult olfactory bulb

1990 • 97 citations

Olfactory neurons express a unique glycosylated form of the neural cell adhesion molecule (N-CAM).

1990 • 95 citations

CMP-NeuNAc:poly-alpha-2,8-sialosyl sialyltransferase and the biosynthesis of polysialosyl units in neural cell adhesion molecules.

1985 • 93 citations

Highly sialylated N-CAM is expressed in adult mouse optic nerve and retina

1990 • 92 citations

Delineation of olfactory pathways in the frog nervous system by unique glycoconjugates and N-CAM glycoforms

1991 • 90 citations

Immunohistological localization of the neural adhesion molecules L1 and N-CAM in the developing hippocampus of the mouse

1990 • 90 citations

Origin of luteinizing hormone-releasing hormone (LHRH) neurons in the chick embryo: Effect of the olfactory placode ablation

1992 • 84 citations

Role of a membranous sialyltransferase complex in the synthesis of surface polymers containing polysialic acid in Escherichia coli. Temperature-induced alteration in the assembly process.

1979 • 83 citations

Immunoglobulin superfamily: Structure, function and relationship to other receptor molecules

1992 • 80 citations

Polysialic acid and N-CAM localisation in embryonic rat kidney: mesenchymal and epithelial elements show different patterns of expression

1990 • 78 citations

Polysialoglycoproteins of Salmonidae fish eggs. Complete structure of 200-kDa polysialoglycoprotein from the unfertilized eggs of rainbow trout (Salmo gairdneri).

1986 • 75 citations

Immunocytological localization of the highly polysialylated form of the neural cell adhesion molecule during development of the murine cerebellar cortex

1990 • 74 citations

Modulation of NCAM expression by transforming growth factor-beta, serum, and autocrine factors.

1990 • 74 citations

Three-dimensional structural analysis of the group B polysaccharide of Neisseria meningitidis 6275 by two-dimensional NMR: the polysaccharide is suggested to exist in helical conformations in solution

1991 • 72 citations

Release of the 120 kDa component of the mouse neural cell adhesion molecule N-CAM from cell surfaces by phosphatidylinositol-specific phospholipase C

1986 • 70 citations

Comparison of the effects of NGF, activators of protein kinase C, and a calcium ionophore on the expression of Thy-1 and N-CAM in PC12 cell cultures.

1988 • 69 citations

Polysialic acid — a glycoprotein carbohydrate involved in neural adhesion and bacterial meningitis

1985 • 68 citations

The nerve growth factor-inducible large external (NILE) glycoprotein and neural cell adhesion molecule (N-CAM) have distinct patterns of expression in the developing rat central nervous system

1987 • 68 citations

Expression of various isoforms of neural cell adhesive molecules and their highly polysialylated counterparts in diseased human muscles

1990 • 68 citations

Growth and Maturation of the Rat Corticospinal Tract

1982 • 67 citations

Interaction of meningococcal group B monoclonal antibody and its Fab fragment with α2-8-linked sialic acid polymers: Requirement of a long oligosaccharide segment for binding

1989 • 66 citations

A developmentally regulated switch in neuronal responsiveness to NCAM and N-cadherin in the rat hippocampus

1992 • 65 citations

Immunoglobulin superfamily molecules in the nervous system

1991 • 61 citations

Heterogeneous distribution of polysialylated neuronal-cell adhesion molecule during post-natal development and in the adult: An immunohistochemical study in the rat brain

1989 • 61 citations

Alterations in the Xenopus retinotectal projection by antibodies to Xenopus N-CAM

1988 • 60 citations

Developmental Expression of Neural Cell Adhesion Molecules of Oligodendrocytes In Vivo and in Culture

1988 • 58 citations

Analysis of high PSA N-CAM expression during mammalian spinal cord and peripheral nervous system development

1991 • 57 citations

C‐CAM (cell‐CAM 105) – a member of the growing immunoglobulin superfamily of cell adhesion proteins

1991 • 52 citations

Neural cell adhesion molecule mediates contact-dependent inhibition of growth of near-diploid mouse fibroblast cell line m5S/1M.

1991 • 52 citations

Up-regulation of embryonic NCAM in an EC cell line by retinoic acid

1989 • 52 citations

Generation of multiple N‐CAM polypeptides from a single gene

1989 • 52 citations

Smooth muscle cells transiently express NCAM

1988 • 50 citations

Alternative Splicing of the Cytoplasmic Domain of Neural Cell Adhesion Molecule Alters Its Ability to Act as a Substrate for Neurite Outgrowth

1992 • 50 citations

Ultrastructural localization of molecular subtypes of immunoreactive neural cell adhesion molecule (NCAM) in the adult rodent striatum

1989 • 50 citations

The anatomy of "paleocortex". A critical review.

1970 • 49 citations

Differential cell adhesion through spatial and temporal variations of NCAM

1986 • 47 citations

Induction of the neural cell adhesion molecule and neuronal aggregation by osteogenic protein 1.

1992 • 47 citations

Biosynthesis and processing of polysialylated NCAM by AtT-20 cells.

1991 • 47 citations

High Degree of NCAM Diversity Generated by Alternative RNA Splicing in Brain and Muscle

1992 • 45 citations

NCAM in developing mouse gonads and ducts

1991 • 44 citations

Mode of neuronal migration of the pontine stream in fetal mice

1990 • 44 citations

Synaptosomal Sialyltransferase Glycosylates Surface Proteins that Are Inaccessible to the Action of Membrane‐Bound Sialidase

1986 • 43 citations

Highly polysialylated NCAM expression in the developing and adult rat spinal cord

1993 • 40 citations

Regulation of neural cell adhesion molecule sialylation state

1991 • 40 citations

Expression of the Neural Cell Adhesion Molecule in Endocrine Cells of the Ovary*

1991 • 40 citations

Localization of mRNA for neural cell adhesion molecule (N-CAM) polypeptides in neural and nonneural tissues by in situ hybridization.

1989 • 39 citations

Neural cell adhesion molecule (N-CAM) expression during cardiac development in the rat

1989 • 34 citations

Mesencephalic dopaminergic cells exhibit increased density of neural cell adhesion molecule and polysialic acid during development

1992 • 33 citations

Polysialic Acid as a Regulator of Cell Interactions

1989 • 30 citations

NCAM gene expression during the development of cerebellum and dentate gyrus in the mouse

1990 • 28 citations

Expression of three drebrin isoforms in the developing nervous system

1990 • 28 citations

Immunohistochemical localization of polysialic acid in tissue sections: differential binding to polynucleotides and DNA of a murine IgG and a human IgM monoclonal antibody.

1990 • 28 citations

Molecular modelling of the immunoglobulin‐like domains of the neural cell adhesion molecule (NCAM): Implications for the positioning of functionally important sugar side chains

1988 • 25 citations

Nerve growth factor receptor immunoreactivity in the rat septohippocampal pathway: A Light and electron microscope investigation

1991 • 25 citations

Cell-cell adhesion molecules

1991 • 24 citations

Immunochemical markers for the frog olfactory neuroepithelium

1990 • 24 citations

The relationship of polysialic acid and the neural cell adhesion molecule N-CAM in Wilms tumor and their subcellular distributions.

1990 • 23 citations

Patterns of N-CAM expression during myogenesis in Xenopus laevis

1988 • 19 citations

5B4‐CAM expression parallels neurite outgrowth and synaptogenesis in the developing rat brain

1992 • 19 citations

Gradient expression of neural cell adhesion molecule (NCAM) in the pontine migratory stream of fetal rats

1992 • 17 citations

Characterization and Cellular Localization of a Developmentally Regulated Rat Neural Sialidase

1986 • 17 citations

Neural cell adhesion molecule is expressed by smooth muscle cells during the development of the rat vascular system

1989 • 11 citations

Localization of neural cell adhesion molecule in denervated muscle to both the plasma membrane and extracellular compartments by immuno-electron microscopy

1988 • 9 citations

Abnormal expression of embryonic neural cell adhesion molecule (N-CAM) in the developing mouse cerebellum after neonatal administration of cytosine arabinoside

1992 • 8 citations

Expression of highly polysialylated neural cell adhesion molecule in calcitonin-producing cells

1993 • 7 citations

Drugs and race-horse performance

1985 • 4 citations

Lack of Cell Density-Dependent Changes in Gangliosides of Rat Primary Culture Neurons

1992 • 2 citations

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