High Degree of NCAM Diversity Generated by Alternative RNA Splicing in Brain and Muscle

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Primer-Directed Enzymatic Amplification of DNA with a Thermostable DNA Polymerase

1988 • 17,059 citations

Serial passaging and differentiation of myogenic cells isolated from dystrophic mouse muscle

1977 • 2,070 citations

A Method for Isolation of Intact, Translationally Active Ribonucleic Acid

1983 • 1,469 citations

RNA editing in brain controls a determinant of ion flow in glutamate-gated channels

1991 • 1,465 citations

Neural Cell Adhesion Molecule: Structure, Immunoglobulin-Like Domains, Cell Surface Modulation, and Alternative RNA Splicing

1987 • 1,134 citations

A novel form of tissue-specific RNA processing produces apolipoprotein-B48 in intestine

1987 • 1,021 citations

ALTERNATIVE SPLICING: A UBIQUITOUS MECHANISM FOR THE GENERATION OF MULTIPLE PROTEIN ISOFORMS FROM SINGLE GENES

1987 • 712 citations

Neural adhesion molecule L1 as a member of the immunoglobulin superfamily with binding domains similar to fibronectin

1988 • 653 citations

Morphoregulatory molecules

1988 • 460 citations

Adhesion molecules and the hierarchy of neural development

1988 • 431 citations

Cell adhesion molecules in vertebrate neural development.

1988 • 386 citations

A year in the life of the immunoglobulin superfamily

1987 • 345 citations

Alternative splicing generates a secreted form of N-CAM in muscle and brain

1988 • 245 citations

Phosphatidylinositol is involved in the membrane attachment of NCAM-120, the smallest component of the neural cell adhesion molecule.

1986 • 232 citations

Isolation and nucleotide sequence of mouse NCAM cDNA that codes for a Mr 79,000 polypeptide without a membrane-spanning region.

1987 • 231 citations

Human muscle neural cell adhesion molecule (N-CAM): Identification of a muscle-specific sequence in the extracellular domain

1987 • 221 citations

Differential exon usage involving an unusual splicing mechanism generates at least eight types of NCAM cDNA in mouse brain.

1989 • 196 citations

Organization of the neural cell adhesion molecule (N-CAM) gene: alternative exon usage as the basis for different membrane-associated domains.

1987 • 193 citations

Sequence of a cDNA clone encoding the polysialic acid-rich and cytoplasmic domains of the neural cell adhesion molecule N-CAM.

1986 • 174 citations

cDNA clones of the neural cell adhesion molecule (N-CAM) lacking a membrane-spanning region consistent with evidence for membrane attachment via a phosphatidylinositol intermediate.

1986 • 158 citations

Identification of a heparin binding domain of the neural cell adhesion molecule N-CAM using synthetic peptides

1989 • 151 citations

Differential splicing and alternative polyadenylation generates distinct NCAM transcripts and proteins in the mouse.

1988 • 146 citations

Skeletal muscle neural cell adhesion molecule (N-CAM): changes in protein and mRNA species during myogenesis of muscle cell lines.

1987 • 124 citations

Polypeptide variation in an N-CAM extracellular immunoglobulin-like fold is developmentally regulated through alternative splicing

1988 • 117 citations

Identification of positive and negative regulatory elements governing cell-type-specific expression of the neural cell adhesion molecule gene.

1990 • 114 citations

Identification of a cDNA clone that contains the complete coding sequence for a 140-kD rat NCAM polypeptide.

1987 • 110 citations

Expression of the unique NCAM VASE exon is independently regulated in distinct tissues during development.

1990 • 110 citations

Isolation of mouse N-CAM-related cDNA: detection and cloning using monoclonal antibodies.

1985 • 108 citations

Techniques for the Genetic Analysis of Brain and Behavior: Focus on the Mouse

1992 • 105 citations

An improved method for the rapid isolation of brain ribonucleic acid

1979 • 101 citations

Proto-oncogene c-myc is expressed in cerebellar neurons at different developmental stages.

1986 • 96 citations

RNA editing in trypanosomes: is there a message?

1990 • 90 citations

Topography of N-CAM structural and functional determinants. II. Placement of monoclonal antibody epitopes.

1986 • 90 citations

At Least 27 Alternatively Spliced Forms of the Neural Cell Adhesion Molecule mRNA Are Expressed during Rat Heart Development

1991 • 88 citations

Alternative splicing of the neural cell adhesion molecule gene generates variant extracellular domain structure in skeletal muscle and brain.

1989 • 77 citations

Tissue specific O-linked glycosylation of the neural cell adhesion molecule (N-CAM)

1989 • 76 citations

Topographic localization of the heparin-binding domain of the neural cell adhesion molecule N-CAM.

1986 • 72 citations

Four exons encode a 93-base-pair insert in three neural cell adhesion molecule mRNAs specific for chicken heart and skeletal muscle.

1988 • 65 citations

Analysis of cDNA clones that code for the transmembrane forms of the mouse neural cell adhesion molecule (NCAM) and are generated by alternative RNA splicing

1987 • 56 citations

Generation of multiple N‐CAM polypeptides from a single gene

1989 • 52 citations

At least 27 alternatively spliced forms of the neural cell adhesion molecule mRNA are expressed during rat heart development.

1991 • 50 citations

Transcription Initiation Sites and Structural Organization of the Extreme 5' Region of the Rat Neural Cell Adhesion Molecule Gene

1990 • 43 citations

Statistical analysis of mammalian pre-mRNA splicing sites

1989 • 41 citations

The N-cam gene is a complex transcriptional unit

1988 • 38 citations

Characterization of cDNA clones defining variant forms of human neural cell adhesion molecule N-CAM

1990 • 36 citations

The muscle specific domain of mouse N-CAM: structure and alternative splicing patterns

1991 • 30 citations

Transcription initiation sites and structural organization of the extreme 5' region of the rat neural cell adhesion molecule gene.

1990 • 30 citations

NCAM-180, the large isoform of the neural cell adhesion molecule of the mouse, is encoded by an alternatively spliced transcript

1988 • 30 citations

The three size classes of mouse NCAM proteins arise from a single gene by a combination of alternative splicing and use of different polyadenylation sites

1988 • 26 citations

Characterization of rat brain NCAM mRNA using DNA oligonucleotide probes

1990 • 17 citations

Physarum — C the difference?

1991 • 6 citations