Elf5 conditional knockout mice reveal its role as a master regulator in mammary alveolar development: Failure of Stat5 activation and functional differentiation in the absence of Elf5

A family of cytokine-inducible inhibitors of signalling

1997 • 2,055 citations

The ETS-domain transcription factor family

2001 • 1,033 citations

Gene expression profiles of human breast cancer progression

2003 • 871 citations

Cre-mediated gene deletion in the mammary gland

1997 • 504 citations

Information networks in the mammary gland

2005 • 486 citations

Cell membrane-associated mucins and their adhesion-modulating property

1992 • 472 citations

IKKα Provides an Essential Link between RANK Signaling and Cyclin D1 Expression during Mammary Gland Development

2001 • 469 citations

A new member of the ETS family fused to EWS in Ewing tumors

1997 • 386 citations

Epigenetic restriction of embryonic cell lineage fate by methylation of Elf5

2008 • 341 citations

Prolactin Controls Mammary Gland Development via Direct and Indirect Mechanisms

1999 • 333 citations

The ETS-domain transcription factor family

1997 • 322 citations

Spatial and temporal expression of the Cre gene under the control of the MMTV-LTR in different lines of transgenic mice.

2001 • 284 citations

On mammary stem cells

2005 • 268 citations

Signal transducer and activator of transcription (Stat) 5 controls the proliferation and differentiation of mammary alveolar epithelium

2001 • 268 citations

The Ets transcription factor Elf5 specifies mammary alveolar cell fate

2008 • 233 citations

REGULATION OF MILK PROTEIN GENE EXPRESSION

1999 • 217 citations

Ablation of β1 integrin in mammary epithelium reveals a key role for integrin in glandular morphogenesis and differentiation

2005 • 215 citations

Loss of the extraembryonic ectoderm inElf5mutants leads to defects in embryonic patterning

2005 • 215 citations

Inhibition and Restoration of Prolactin Signal Transduction by Suppressors of Cytokine Signaling

1999 • 197 citations

Promiscuous gene expression patterns in single medullary thymic epithelial cells argue for a stochastic mechanism

2008 • 191 citations

Impaired differentiation and lactational failure ofErbb4-deficient mammary glands identify ERBB4 as an obligate mediator of STAT5

2003 • 155 citations

Socs2 and Elf5 Mediate Prolactin-Induced Mammary Gland Development

2006 • 152 citations

Key stages in mammary gland development - The alveolar switch: coordinating the proliferative cues and cell fate decisions that drive the formation of lobuloalveoli from ductal epithelium

2006 • 144 citations

Elf5 is essential for early embryogenesis and mammary gland development during pregnancy and lactation

2005 • 143 citations

Ets transcription factors and human disease

1998 • 141 citations

Lactation defect in mice lacking the helix-loop-helix inhibitor Id2

2000 • 122 citations

Perturbation of beta 1-integrin function alters the development of murine mammary gland

1998 • 120 citations

Investigation of the Transcriptional Changes Underlying Functional Defects in the Mammary Glands of Prolactin Receptor Knockout Mice

2003 • 111 citations

Disruption of Steroid and Prolactin Receptor Patterning in the Mammary Gland Correlates with a Block in Lobuloalveolar Development

2002 • 106 citations

Alveolar and Lactogenic Differentiation

2006 • 106 citations

A β-catenin survival signal is required for normal lobular development in the mammary gland

2003 • 92 citations

A novel transcription factor, ELF5, belongs to the ELF subfamily of ETS genes and maps to human chromosome 11p13–15, a region subject to LOH and rearrangement in human carcinoma cell lines

1998 • 82 citations

Multiple chromosomal mechanisms generate an EWS/FLI1 or an EWS/ERG fusion gene in Ewing tumors

1997 • 67 citations

Claudin 7 expression and localization in the normal murine mammary gland and murine mammary tumors

2005 • 65 citations

Helix-loop-helix proteins in mammary gland development and breast cancer.

2003 • 65 citations

Expression of Terminal Differentiation Proteins Defines Stages of Mouse Mammary Gland Development

2006 • 63 citations

SOCS-1, -2, -3: selective targets and functions downstream of the prolactin receptor

1999 • 59 citations

Temporally regulated overexpression of parathyroid hormone-related protein in the mammary gland reveals distinct fetal and pubertal phenotypes

2001 • 58 citations

Elf5 is an epithelium‐specific, fibroblast growth factor–sensitive transcription factor in the embryonic lung

2007 • 55 citations

Proteotyping of Mammary Tissue from Transgenic and Gene Knockout Mice with Immunohistochemical Markers: a Tool To Define Developmental Lesions

2003 • 52 citations

Mouse Mammary Epithelial Cells Express the Na-K-Cl Cotransporter, NKCC1: Characterization, Localization, and Involvement in Ductal Development and Morphogenesis

2002 • 51 citations

Transcriptional Networks in the Liver: Hepatocyte Nuclear Factor 6 Function Is Largely Independent of Foxa2

2005 • 44 citations

A major site of expression of the ets transcription factor Elf5 is epithelia of exocrine glands

2004 • 39 citations

Mammary Epithelial Cells Are Not Able to Undergo Pregnancy-Dependent Differentiation in the Absence of the Helix-Loop-Helix Inhibitor Id2

2002 • 37 citations

The Elf Group of Ets-Related Transcription Factors

2002 • 32 citations

Determination of the consensus DNA-binding sequence and a transcriptional activation domain for ESE-2

2006 • 31 citations

Loss of the LIM domain protein Lmo4 in the mammary gland during pregnancy impedes lobuloalveolar development

2005 • 27 citations

Generation and analysis of Elf5-LacZ mouse: unique and dynamic expression of Elf5 (ESE-2) in the inner root sheath of cycling hair follicles

2007 • 19 citations

Differentiation‐specific transcriptional regulation of the ESE‐2 gene by a novel keratinocyte‐restricted factor

2005 • 17 citations

Epithelium-specific ets transcription factor 2 upregulates cytokeratin 18 expression in pulmonary epithelial cells through an interaction with cytokeratin 18 intron 1

2005 • 9 citations