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Multiple chromosomal mechanisms generate an EWS/FLI1 or an EWS/ERG fusion gene in Ewing tumors

Data up to Jan 2025

Published1997
Citations67
References33

Total Citations Per Year

Abstract

References (33)

Gene fusion with an ETS DNA-binding domain caused by chromosome translocation in human tumours

1992 • 1,787 citations

The Ewing Family of Tumors -- A Subgroup of Small-Round-Cell Tumors Defined by Specific Chimeric Transcripts

1994 • 1,069 citations

A second Ewing's sarcoma translocation, t(21;22), fuses the EWS gene to another ETS–family transcription factor, ERG

1994 • 727 citations

Combinatorial generation of variable fusion proteins in the Ewing family of tumours.

1993 • 537 citations

Chromosomes in Ewing's sarcoma. I. An evaluation of 85 cases and remarkable consistency of t(11;22)(q24;q12)

1988 • 468 citations

A variant Ewing's sarcoma translocation (7;22) fuses the EWS gene to the ETS gene ETV1.

1995 • 466 citations

Cytogenetic characterization of selected small round cell tumors of childhood

1986 • 316 citations

Cloning and characterization of the Ewing's sarcoma and peripheral neuroepithelioma t(11;22) translocation breakpoints

1992 • 306 citations

Chromosome study of Ewing's Sarcoma (ES) cell lines. Consistency of a reciprocal translocation t(11;22)(q24;q12)

1984 • 292 citations

A Novel Chimera Gene betweenEWSandE1A-F, Encoding the Adenovirus E1A Enhancer-Binding Protein, in Extraosseous Ewing's Sarcoma

1996 • 170 citations

EWS-erg and EWS-Fli1 fusion transcripts in Ewing's sarcoma and primitive neuroectodermal tumors with variant translocations.

1994 • 161 citations

Is the chromosomal region 9q34 always involved in variants of the Ph1 translocation?

1984 • 158 citations

Genomic diversity correlates with clinical variation in Ph′-negative chronic myeloid leukaemia

1986 • 145 citations

Chromosome Changes in Soft Tissue Sarcomas<xref ref-type="fn" rid="FN2">2</xref>

1984 • 132 citations

Rearrangement of the bcr Gene in Philadelphia-Chromosome-Negative Chronic Myeloid Leukemia

1987 • 103 citations

Breakpoint heterogeneity in t(10;11) translocation in AML-M4/M5 resulting in fusion of AF10 and MLL is resolved by fluorescent in situ hybridization analysis.

1995 • 86 citations

Rearrangement of the bcr gene in Philadelphia chromosome-negative chronic myeloid leukemia

1986 • 85 citations

Translocation of c-abl to “Masked” Ph in chronic myeloid leukemia

1985 • 80 citations

Interphase molecular cytogenetics of Ewing's sarcoma and peripheral neuroepithelioma t(11;22) with flanking and overlapping cosmid probes

1994 • 68 citations

Cytogenetic and molecular analysis in Philadelphia negative CML

1989 • 65 citations

Ph-negative chronic myeloid leukemia: molecular analysis of ABL insertion into M-BCR on chromosome 22

1990 • 63 citations

Physical mapping by FISH of the DiGeorge critical region (DGCR): involvement of the region in familial cases.

1993 • 59 citations

Unicolor and bicolor in situ hybridization in the diagnosis of peripheral neuroepithelioma and related tumors

1992 • 53 citations

Mapping of human chromosome 22 with a panel of somatic cell hybrids

1991 • 49 citations

t(11;22) and Other Chromosomal Rearrangements in Ewing's Sarcoma<xref ref-type="fn" rid="FN2">2</xref>

1986 • 40 citations

Rejoining between 9q+ and Philadelphia chromosomes results in normal-looking chromosomes 9 and 22 in Ph1-negative chronic myelocytic leukemia

1989 • 36 citations

A complex chromosome rearrangement forms the BCR‐ABL fusion gene in leukemic cells with a normal karyotype

1991 • 29 citations

Mapping the Down Syndrome Chromosome Region

1993 • 26 citations

Cloning of six new genes with zinc finger motifs mapping to short and long arms of human acrocentric chromosome 22 (p and q11.2)

1992 • 24 citations

Complexity of an apparently simple variant Ph translocation in chronic myeloid leukemia

1987 • 20 citations

Molecular cytogenetic analysis of a complex t(10;22;11) translocation in ewing's sarcoma

1992 • 19 citations

Rapid isolation of cosmids from defined subregions by differential Alu-PCR hybridization on chromosome 22-specific library

1992 • 14 citations

[Cytogenetic data on sarcomas of the bone and soft tissue].

1988 • 3 citations

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Multiple chromosomal mechanisms generate an EWS/FLI1 or an EWS/ERG fusion gene in Ewing… (1997) – Cancer Genetics and Cytogenetics | Metascience Observatory Explorer