Interaction of nuclear factors with the upstream region of the alpha-subunit gene of chicken muscle acetylcholine receptor: variations with muscle differentiation and denervation.

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

[57] Sequencing end-labeled DNA with base-specific chemical cleavages

1980 • 15,302 citations

Organization and Expression of Eucaryotic Split Genes Coding for Proteins

1981 • 4,730 citations

Equilibria and kinetics of lac repressor-operator interactions by polyacrylamide gel electrophoresis

1981 • 2,828 citations

DNAase footprinting a simple method for the detection of protein-DNA binding specificity

1978 • 2,092 citations

A gel electrophoresis method for quantifying the binding of proteins to specific DNA regions: application to components of the Escherichia coli lactose operon regulatory system

1981 • 1,991 citations

Regulation of Inducible and Tissue-Specific Gene Expression

1987 • 1,640 citations

Transcription factor AP-2 mediates induction by two different signal-transduction pathways: Protein kinase C and cAMP

1987 • 1,391 citations

Enhancer-dependent expression of human kappa immunoglobulin genes introduced into mouse pre-B lymphocytes by electroporation.

1984 • 889 citations

Multiple Point Mutations Affecting the Simian Virus 40 Enhancer

1983 • 883 citations

Control of acetylcholine receptors in skeletal muscle

1979 • 770 citations

A study of supersensitivity in denervated mammalian skeletal muscle

1959 • 737 citations

Identification of a rat liver nuclear protein that binds to the enhancer core element of three animal viruses.

1987 • 631 citations

Multiple specific contacts between a mammalian transcription factor and its cognate promoters

1984 • 565 citations

Mutually exclusive interaction of the CCAAT-binding factor and of a displacement protein with overlapping sequences of a histone gene promoter

1987 • 407 citations

Multiple cis- and trans-acting elements mediate the transcriptional response to phorbol esters

1987 • 379 citations

The acetylcholine receptor: an "allosteric" membrane protein.

1979 • 256 citations

Calcitonin gene-related peptide and muscle activity regulate acetylcholine receptor alpha-subunit mRNA levels by distinct intracellular pathways.

1987 • 247 citations

Junctional and extra‐junctional acetylcholine receptors in skeletal muscle fibres

1960 • 232 citations

Several distinct "CCAAT" box binding proteins coexist in eukaryotic cells.

1988 • 230 citations

Nicotinic acetylcholine receptors in vertebrate muscle: Properties, distribution and neural control

1985 • 229 citations

Detection of the nicotinic acetylcholine receptor alpha-subunit mRNA by in situ hybridization at neuromuscular junctions of 15-day-old chick striated muscles.

1988 • 217 citations

Tissue-specific expression is conferred by a sequence from the 5′ end of the rat albumin gene.

1984 • 202 citations

Development of the neuromuscular junction in the chick embryo: The number, distribution, and stability of acetylcholine receptors

1977 • 199 citations

Denervation supersensitivity in skeletal muscle: analysis with a cloned cDNA probe.

1984 • 191 citations

Two different factors bind to the alpha-domain of the polyoma virus enhancer, one of which also interacts with the SV40 and c-fos enhancers.

1987 • 179 citations

A common positive trans-acting factor binds to enhancer sequences in the promoters of mouse H-2 and beta 2-microglobulin genes.

1987 • 169 citations

Activity regulates the levels of acetylcholine receptor alpha-subunit mRNA in cultured chicken myotubes.

1985 • 153 citations

Neurite outgrowth from embryonic chicken spinal neurons is promoted by media conditioned by muscle cells.

1981 • 141 citations

Specific interaction of cellular factors with the B enhancer of polyoma virus.

1985 • 124 citations

Muscle acetylcholine receptor biosynthesis. Regulation by transcript availability.

1987 • 107 citations

Constitutive synthesis of activator protein 1 transcription factor after viral transformation of mouse fibroblasts.

1988 • 103 citations

Transcriptional regulation of nicotinic acetylcholine receptor genes during muscle development.

1986 • 96 citations

Regulation of acetylcholine receptor transcript expression during development in Xenopus laevis

1988 • 93 citations

Muscle denervation increases the levels of two mRNAs coding for the acetylcholine receptor alpha-subunit

1985 • 93 citations

A 5′-Flanking Region of the Chicken Acetylcholine Receptor α-Subunit Gene Confers Tissue Specificity and Developmental Control of Expression in Transfected Cells

1987 • 90 citations

Tissue restricted and stage specific transcription is maintained within 411 nucleotides flanking the 5′ end of the chicken α-skeletal actin gene

1986 • 86 citations

Transcription Elements and Factors of Rna Polymerase B Promoters of Higher Eukaryote

1988 • 82 citations

Functional activity of the two promoters of the myosin alkali light chain gene in primary muscle cell cultures: comparison with other muscle gene promoters and other culture systems

1988 • 74 citations

Evolution of cholinergic proteins in developing slow and fast skeletal muscles in chick embryo.

1980 • 74 citations

A cell type-specific enhancer drives expression of the chick muscle acetylcholine receptor α-subunit gene

1988 • 71 citations

Synthesis and assembly of acetylcholine receptor, a multisubunit membrane glycoprotein

1986 • 65 citations

Quantitation of an alpha subunit splicing intermediate: evidence for transcriptional activation in the control of acetylcholine receptor expression in denervated chick skeletal muscle.

1987 • 51 citations

Differential expression of nicotinic acetylcholine receptor genes in innervated and denervated chicken muscle.

1987 • 47 citations

Acetylcholine receptor synthesis rate and levels of receptor subunit messenger RNAs in chick muscle

1988 • 41 citations

Quantitative studies on the localization of the cholinergic receptor protein in the normal and denervated electroplaque from Electrophorus electricus.

1978 • 40 citations

Molecular analysis of the interaction between an enhancer binding factor and its DNA target

1986 • 40 citations

Stepwise Activation of the Mouse Acetylcholine Receptor δ- and ϒ-Subunit Genes in Clonal Cell Lines

1988 • 32 citations

Evidence for degradation of the acetylcholine (nicotinic) receptor in skeletal muscle during the development of the chick embryo

1977 • 31 citations

Transcriptional regulation of nicotinic acetylcholine receptor genes: identification of control elements of a γ-subunit gene

1987 • 23 citations

DNase I-hypersensitive sites surround the mouse acetylcholine receptor delta-subunit gene.

1986 • 23 citations

Upstream Regulatory Region for Inducible Expression of the Chicken Skeletal Myosin Alkali Light-Chain Gene

1988 • 19 citations