Enhancer elements directing cell-type-specific expression of cytokeratin genes and changes of the epithelial cytoskeleton by transfections of hybrid cytokeratin genes.

[57] Sequencing end-labeled DNA with base-specific chemical cleavages

1980 • 15,302 citations

A new technique for the assay of infectivity of human adenovirus 5 DNA

1973 • 9,740 citations

Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells.

1982 • 8,069 citations

The catalog of human cytokeratins: Patterns of expression in normal epithelia, tumors and cultured cells

1982 • 5,272 citations

Recombinant Genomes Which Express Chloramphenicol Acetyltransferase in Mammalian Cells

1982 • 3,106 citations

CAT constructions with multiple unique restriction sites for the functional analysis of eukaryotic promoters and regulatory elements

1987 • 1,792 citations

MOLECULAR AND CELLULAR BIOLOGY OF INTERMEDIATE FILAMENTS

1988 • 1,395 citations

Changes in keratin gene expression during terminal differentiation of the keratinocyte

1980 • 1,059 citations

Multiple Point Mutations Affecting the Simian Virus 40 Enhancer

1983 • 883 citations

Tumor diagnosis by intermediate filament typing: a novel tool for surgical pathology.

1983 • 863 citations

Regulation of terminal differentiation of cultured human keratinocytes by vitamin A

1981 • 756 citations

Classification of human epithelia and their neoplasms using monoclonal antibodies to keratins: strategies, applications, and limitations.

1985 • 735 citations

Introns increase transcriptional efficiency in transgenic mice.

1988 • 733 citations

A new dominant hybrid selective marker for higher eukaryotic cells

1981 • 662 citations

Diversity of cytokeratins

1981 • 611 citations

Antibody to prekeratin

1978 • 496 citations

The molecular biology of intermediate filaments

1985 • 475 citations

Patterns of Expression and Organization of Cytokeratin Intermediate Filaments

1985 • 420 citations

Differentiation-related Patterns of Expression of Proteins of Intermediate-size Filaments in Tissues and Cultured Cells

1982 • 419 citations

Self-assembly of bovine epidermal keratin filaments in vitro

1976 • 388 citations

Pair formation and promiscuity of cytokeratins: formation in vitro of heterotypic complexes and intermediate-sized filaments by homologous and heterologous recombinations of purified polypeptides.

1985 • 343 citations

Retinoids as important regulators of terminal differentiation: examining keratin expression in individual epidermal cells at various stages of keratinization.

1987 • 343 citations

Keratin Antigens in Differentiating Skin

1985 • 330 citations

Glucocorticoid responsiveness of the transcriptional enhancer of Moloney Murine Sarcoma Virus

1986 • 262 citations

The role of keratin subfamilies and keratin pairs in the formation of human epidermal intermediate filaments.

1986 • 259 citations

Monoclonal Antibody Studies of Mammalian Epithelial Keratins: A Review ^a

1985 • 258 citations

Patterns of expression of trichocytic and epithelial cytokeratins in mammalian tissues. I. Human and bovine hair follicles

1988 • 251 citations

Intermediate filament proteins in nonfilamentous structures: Transient disintegration and inclusion of subunit proteins in granular aggregates

1982 • 250 citations

The expression of mutant epidermal keratin cDNAs transfected in simple epithelial and squamous cell carcinoma lines.

1987 • 237 citations

Nuclear lamins and cytoplasmic intermediate filament proteins: A growing multigene family

1987 • 235 citations

Cytoskeletal components of lymphoid organs

1987 • 234 citations

A nerve growth factor-regulated messenger RNA encodes a new intermediate filament protein.

1988 • 232 citations

Cytokeratins of normal epithelia and some neoplasms of the female genital tract.

1983 • 224 citations

Peripherin, a New Member of the Intermediate Filament Protein Family

1983 • 221 citations

The complement of native α-keratin polypeptides of hair-forming cells: A subset of eight polypeptides that differ from epithelial cytokeratins

1986 • 196 citations

Heterotypic tetramer (A2D2) complexes of non-epidermal keratins isolated from cytoskeletons of rat hepatocytes and hepatoma cells

1984 • 194 citations

Regulated expression of differentiation-associated keratins in cultured epidermal cells detected by monospecific antibodies to unique peptides of mouse epidermal keratins

1987 • 187 citations

A subfamily of relatively large and basic cytokeratin polypeptides as defined by peptide mapping is represented by one or several polypeptides in epithelial cells.

1982 • 186 citations

Differences of expression of cytoskeletal proteins in cultured rat hepatocytes and hepatoma cells

1981 • 185 citations

Cytokeratins in certain endothelial and smooth muscle cells of two taxonomically distant vertebrate species, Xenopus laevis and man

1987 • 183 citations

Monoclonal antibodies to various acidic (type I) cytokeratins of stratified epithelia

1986 • 179 citations

Disruption of the keratin filament network during epithelial cell division.

1982 • 172 citations

Cytokeratin polypeptide patterns of different epithelia of the human male urogenital tract: immunofluorescence and gel electrophoretic studies.

1985 • 171 citations

Remarkable conservation of structure among intermediate filament genes

1984 • 169 citations

Evidence for posttranscriptional regulation of the keratins expressed during hyperproliferation and malignant transformation in human epidermis.

1986 • 164 citations

Tissue type-specific expression of intermediate filament proteins in a cultured epithelial cell line from bovine mammary gland

1983 • 145 citations

A group of type I keratin genes on human chromosome 17: characterization and expression.

1988 • 142 citations

Delimitation and characterization of cis-acting DNA sequences required for the regulated expression and transcriptional control of the chicken skeletal alpha-actin gene.

1986 • 137 citations

Coordinate control by vitamin A of keratin gene expression in human keratinocytes.

1985 • 133 citations

A 3' enhancer contributes to the stage-specific expression of the human beta-globin gene.

1987 • 128 citations

Chapter 2 The Human Keratin Genes and Their Differential Expression

1987 • 126 citations

Mutational analysis of the chicken beta-globin enhancer reveals two positive-acting domains.

1988 • 120 citations

Cytokeratin patterns of human oral epithelia: Differences in cytokeratin synthesis in gingival epithelium and the adjacent alveolar mucosa

1985 • 118 citations

Characterization of the hamster desmin gene: Expression and formation of desmin filaments in nonmuscle cells after gene transfer

1985 • 112 citations

Differentially expressed bovine cytokeratin genes. Analysis of gene linkage and evolutionary conservation of 5′-upstream sequences.

1987 • 112 citations

Cloning of the human keratin 18 gene and its expression in nonepithelial mouse cells.

1988 • 111 citations

Expression and assembly of a human neurofilament protein in transgenic mice provide a novel neuronal marking system.

1987 • 107 citations

Monoclonal antibody analysis of bovine epithelial keratins. Specific pairs as defined by coexpression.

1986 • 107 citations

Organisation of the polypeptide chains in mammalian keratin

1976 • 104 citations

Functional Analysis and Growth Factor Regulation of the Human Vimentin Promoter

1987 • 96 citations

The transfection of epidermal keratin genes into fibroblasts and simple epithelial cells: Evidence for inducing a type I keratin by a type II gene

1987 • 96 citations

Identification of two types of keratin polypeptides within the acidic cytokeratin subfamily I

1984 • 95 citations

De novo synthesis and specific assembly of keratin filaments in nonepithelial cells after microinjection of mRNA for epidermal keratin

1983 • 89 citations

Regulation of human mesothelial cell differentiation: opposing roles of retinoids and epidermal growth factor in the expression of intermediate filament proteins.

1987 • 80 citations

A 40-base-pair sequence in the 3' end of the beta-actin gene regulates beta-actin mRNA transcription during myogenesis.

1988 • 77 citations

Upstream regions of the hamster desmin and vimentin genes regulate expression during in vitro myogenesis.

1987 • 70 citations

Keratin filament disruption in interphase and mitotic cells--how is it induced?

1987 • 67 citations

The chicken vimentin gene. Nucleotide sequence, regulatory elements, and comparison to the hamster gene.

1987 • 66 citations

Nonepidermal members of the keratin multigene family: cDNA sequences and in situ localization of the mRNAs

1986 • 64 citations

Characterization and regulation in the expression of a gene coding for the intermediate filament protein desmin.

1984 • 61 citations

Integration of different keratins into the same filament system after microinjection of mRNA for epidermal keratins into kidney epithelial cells

1984 • 61 citations

Cell type-specific expression of bovine keratin genes as demonstrated by the use of complementary DNA clones

1984 • 60 citations

Vimentin gene: expression in human lymphocytes and in Burkitt's lymphoma cells.

1986 • 58 citations

DNA-binding site for two skeletal actin promoter factors is important for expression in muscle cells.

1988 • 58 citations

Complete sequence of a bovine type I cytokeratin gene: conserved and variable intron positions in genes of polypeptides of the same cytokeratin subfamily.

1985 • 52 citations

Characterization of bovine keratin genes: similarities of exon patterns in genes coding for different keratins.

1984 • 50 citations

An epithelial cell line with elongated myoid morphology derived from bovine mammary gland

1983 • 45 citations

intermediate filament formation after transfection with modified hamster vimentin and desmin genes

1987 • 39 citations

A Group of Type I Keratin Genes on Human Chromosome 17: Characterization and Expression

1988 • 38 citations

Cloning of the Human Keratin 18 Gene and Its Expression in Nonepithelial Mouse Cells

1988 • 35 citations

Tissue-specific expression of a vimentin-desmin hybrid gene in transgenic mice.

1988 • 32 citations

Chapter 9 Regulation of Keratin Gene Expression During Differentiation of Epidermal and Vaginal Epithelial Cells

1987 • 32 citations

Delimitation and Characterization of cis-Acting DNA Sequences Required for the Regulated Expression and Transcriptional Control of the Chicken Skeletal α-Actin Gene

1986 • 25 citations

Expression of transfected vimentin genes in differentiating murine erythroleukemia cells reveals divergent cis-acting regulation of avian and mammalian vimentin sequences.

1987 • 24 citations

DNA-Binding Site for Two Skeletal Actin Promoter Factors Is Important for Expression in Muscle Cells

1988 • 21 citations

Expression of Transfected Vimentin Genes in Differentiating Murine Erythroleukemia Cells Reveals Divergent cis-Acting Regulation of Avian and Mammalian Vimentin Sequences

1987 • 7 citations

Chapter 4 The Experimental Manipulation of Keratin Expression and Organization in Epithelial Cells and Somatic Cell Hybrids

1987 • 7 citations