Multiple 5'-flanking regions of the human alpha-skeletal actin gene synergistically modulate muscle-specific expression.

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

Molecular cloning: A laboratory manual

1990 • 85,659 citations

A new technique for the assay of infectivity of human adenovirus 5 DNA

1973 • 9,740 citations

Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells.

1982 • 8,069 citations

Organization and Expression of Eucaryotic Split Genes Coding for Proteins

1981 • 4,730 citations

Recombinant Genomes Which Express Chloramphenicol Acetyltransferase in Mammalian Cells

1982 • 3,106 citations

Serial passaging and differentiation of myogenic cells isolated from dystrophic mouse muscle

1977 • 2,070 citations

The structure and evolution of the human β-globin gene family

1980 • 1,398 citations

DNA-dependent transcription of adenovirus genes in a soluble whole-cell extract.

1980 • 1,285 citations

The ovalbumin gene - sequence of putative control regions

1980 • 996 citations

Two distinct enhancers with different cell specificities coexist in the regulatory region of polyoma

1984 • 891 citations

A human beta-actin expression vector system directs high-level accumulation of antisense transcripts.

1987 • 767 citations

Cell-Specific Expression of the Rat Insulin Gene: Evidence for Role of Two Distinct 5′ Flanking Elements

1985 • 698 citations

Host-specific activation of transcription by tandem repeats from simian virus 40 and Moloney murine sarcoma virus.

1982 • 625 citations

Upstream regions of the human cardiac actin gene that modulate its transcription in muscle cells: presence of an evolutionarily conserved repeated motif.

1986 • 432 citations

An operator at -280 base pairs that is required for repression of araBAD operon promoter: addition of DNA helical turns between the operator and promoter cyclically hinders repression.

1984 • 375 citations

Diversity of Alpha-Fetoprotein Gene Expression in Mice Is Generated by a Combination of Separate Enhancer Elements

1987 • 315 citations

The Structure and Evolution of the Human /?-Globin Gene Family

1980 • 301 citations

A fetal skeletal muscle actin mRNA in the mouse and its identity with cardiac actin mRNA

1982 • 295 citations

Human β-interferon gene expression is regulated by an inducible enhancer element

1985 • 283 citations

The SV40 enhancer can be dissected into multiple segments, each with a different cell type specificity.

1987 • 265 citations

Transcriptional "silencer" element in rat repetitive sequences associated with the rat insulin 1 gene locus.

1986 • 257 citations

The role of the κ enhancer and its binding factor NF-κB in the developmental regulation of κ gene transcription

1987 • 247 citations

Heat shock regulatory elements function as an inducible enhancer in the xenopus hsp70 gene and when linked to a heterologous promoter

1986 • 239 citations

α-Skeletal and α-Cardiac Actin Genes Are Coexpressed in Adult Human Skeletal Muscle and Heart

1983 • 237 citations

Specific in vitro initiation of transcription on conalbumin and ovalbumin genes and comparison with adenovirus-2 early and late genes

1980 • 217 citations

Delimitation and properties of DNA sequence: required for the regulated expression of human interferon-β gene

1985 • 216 citations

Cell-type specific protein binding to the enhancer of simian virus 40 in nuclear extracts

1986 • 209 citations

Multiple regulatory elements in the intergenic region between the alpha-fetoprotein and albumin genes.

1986 • 205 citations

Duplicated CArG Box Domains Have Positive and Mutually Dependent Regulatory Roles in Expression of the Human α-Cardiac Actin Gene

1987 • 192 citations

Cardiac actin is the major actin gene product in skeletal muscle cell differentiation in vitro.

1984 • 188 citations

Cell-specific expression of a transfected human α1-antitrypsin gene

1985 • 188 citations

A 46-nucleotide promoter segment from an IFN-α gene renders an unrelated promoter inducible by virus

1985 • 185 citations

Regulation of rat insulin 1 gene expression: evidence for negative regulation in nonpancreatic cells.

1986 • 178 citations

Transient gene expression control: effects of transfected DNA stability and trans-activation by viral early proteins.

1985 • 174 citations

Sequential expression of chicken actin genes during myogenesis.

1986 • 169 citations

Localization of DNA sequences necessary for transcription of the rabbit β-globin gene in vitro

1981 • 158 citations

Expression of the genes coding for the skeletal muscle and cardiac actins in the heart

1984 • 157 citations

Coordinate accumulation of contractile protein mRNAs during myoblast differentiation

1979 • 153 citations

Molecular Biology of Muscle Development

1987 • 151 citations

Upstream sequences required for tissue-specific activation of the cardiac actin gene in Xenopus laevis embryos.

1986 • 144 citations

Delimitation and characterization of cis-acting DNA sequences required for the regulated expression and transcriptional control of the chicken skeletal alpha-actin gene.

1986 • 137 citations

Lens-specific expression of the chloramphenicol acetyltransferase gene promoted by 5' flanking sequences of the murine alpha A-crystallin gene in explanted chicken lens epithelia.

1985 • 132 citations

Accurate transcription initiation on a purified mouse β-globin DNA fragment in a cell-free system

1980 • 126 citations

Developmentally regulated expression of chimeric genes containing muscle actin DNA sequences in transfected myogenic cells.

1984 • 123 citations

alpha-skeletal and alpha-cardiac actin genes are coexpressed in adult human skeletal muscle and heart.

1983 • 121 citations

Differential patterns of transcript accumulation during human myogenesis.

1987 • 120 citations

The lysozyme enhancer: cell-specific activation of the chicken lysozyme gene by a far-upstream DNA element.

1986 • 118 citations

Expression and regulation of chicken actin genes introduced into mouse myogenic and nonmyogenic cells.

1984 • 114 citations

Two-level regulation of cardiac actin gene transcription: muscle-specific modulating factors can accumulate before gene activation.

1986 • 108 citations

Cell-type-specific transcription of an immunoglobulin kappa light chain gene in vitro.

1986 • 96 citations

Control of transcription initiation in vitro requires binding of a transcription factor to the distal promoter of the ovalbumin gene.

1986 • 95 citations

Isolation and characterization of cDNA clones for human skeletal muscle α actin

1983 • 93 citations

Structure and cell-specific expression of a cloned human retinol binding protein gene: the 5′-flanking region contains hepatoma specific transcriptional signals.

1985 • 93 citations

Transcriptional Control of the Mouse α₂(I) Collagen Gene: Functional Deletion Analysis of the Promoter and Evidence for Cell-Scific Expression

1986 • 89 citations

Tissue restricted and stage specific transcription is maintained within 411 nucleotides flanking the 5′ end of the chicken α-skeletal actin gene

1986 • 86 citations

Strong homology in promoter and 3′-untranslated regions of chick and rat α-actin genes

1983 • 84 citations

Contribution of Promoter to Tissue-Specific Expression of the Mouse Immunoglobulin Kappa Gene

1985 • 76 citations

Specific 5′ flanking sequences are required for faithful initiation of in vitro transcription of the ovalbumin gene

1981 • 74 citations

Tissue-specific transcription enhancement of the fibroin gene characterized by cell-free systems.

1986 • 66 citations

Developmentally regulated expression of a chicken muscle-specific gene in stably transfected rat myogenic cells.

1985 • 58 citations

DNAase I sensitivity of genes expressed during myogenesis

1982 • 56 citations

Two-Level Regulation of Cardiac Actin Gene Transcription: Muscle-Specific Modulating Factors Can Accumulate before Gene Activation

1986 • 55 citations

In vitro transcription of normal, mutant, and truncated mouse alpha-globin genes.

1980 • 55 citations

DNA sequences responsible for tissue-specific expression of a chicken alpha-crystallin gene in mouse lens cells.

1985 • 45 citations

Control of Transcription Initiation In Vitro Requires Binding of a Transcription Factor to the Distal Promoter of the Ovalbumin Gene

1986 • 40 citations

Definition of the ovalbumin gene promoter by transfer of an ovalglobin fusion gene into cultured cells

1983 • 37 citations

Differential Patterns of Transcript Accumulation during Human Myogenesis

1987 • 35 citations

Regulation of a human cardiac actin gene introduced into rat L6 myoblasts suggests a defect in their myogenic program.

1986 • 30 citations

Transient GeneExpression Control: Effects ofTransfected DNA Stability andtrans-Activation byViral Early Proteins

1985 • 24 citations

Characterization of 5'-flanking region of heart myosin light chain 2A gene. Structural and functional evidence for promoter activity.

1986 • 22 citations

Frequency of the methane-stabilized He–Ne laser at 88 THz measured to ±3 parts in 1011

1980 • 15 citations

Regulation of a Human Cardiac Actin Gene Introduced Into Rat L6 Myoblasts Suggests a Defect in Their Myogenic Program

1986 • 13 citations

Deleted Work

1955 • 0 citations