Purinergic agonist ATP is a comitogen in thyroid FRTL-5 cells

A new generation of Ca2+ indicators with greatly improved fluorescence properties.

1985 • 21,873 citations

Thapsigargin, a tumor promoter, discharges intracellular Ca2+ stores by specific inhibition of the endoplasmic reticulum Ca2(+)-ATPase.

1990 • 3,250 citations

Signal transduction via the MAP kinases: proceed at your own RSK.

1993 • 1,262 citations

Culture of hormone-dependent functional epithelial cells from rat thyroids.

1980 • 959 citations

Calcium Channels in Excitable Cell Membranes

1983 • 725 citations

Cyclic AMP activates the mitogen-activated protein kinase cascade in PC12 cells.

1994 • 326 citations

Intracellular Ca2+ pool content is linked to control of cell growth.

1993 • 260 citations

Activation of MAP kinases by calcium-dependent and calcium-independent pathways. Stimulation by thapsigargin and epidermal growth factor.

1992 • 240 citations

The Relationship of Growth and Adenylate Cyclase Activity in Cultured Thyroid Cells: Separate Bioeffects of Thyrotropin

1983 • 204 citations

Calmodulin is involved in regulation of cell proliferation.

1987 • 183 citations

Phorbol Esters Stimulate Growth and Inhibit Differentiation in Cultured Thyroid Cells*

1985 • 142 citations

Thyrotropin and dibutyryl cyclic AMP increase levels of c-myc and c-fos mRNAs in cultured rat thyroid cells.

1986 • 140 citations

Extracellular ATP and ADP stimulate proliferation of porcine aortic smooth muscle cells

1992 • 140 citations

Association of the changes in cytosolic Ca2+ and iodide efflux induced by thyrotropin and by the stimulation of alpha 1-adrenergic receptors in cultured rat thyroid cells.

1985 • 138 citations

Phosphorylation of mitogen-activated protein kinases is involved in the epidermal growth factor and phorbol ester, but not in the thyrotropin/cAMP, thyroid mitogenic pathway.

1993 • 119 citations

Sympathetic purinergic transmission in small blood vessels

1988 • 115 citations

Inhibition by Islet-Activating Protein, Pertussis Toxin, of P₂-Purinergic Receptor-Mediated Iodide Efflux and Phosphoinositide Turnover in FRTL-5 Cells*

1988 • 101 citations

A Permissive Role of Pertussis Toxin Substrate G-protein in P2-purinergic Stimulation of Phosphoinositide Turnover and Arachidonate Release in FRTL-5 Thyroid Cells

1989 • 99 citations

Feedback regulation of mitogen-activated protein kinase kinase kinase activity of c-Raf-1 by insulin and phorbol ester stimulation.

1994 • 97 citations

Demonstration of the production and physiological role of insulin-like growth factor II in rat thyroid follicular cells in culture.

1988 • 90 citations

Alpha 1-adrenergic stimulation of arachidonic acid release and metabolism in a rat thyroid cell line. Mediation of cell replication by prostaglandin E2.

1986 • 89 citations

Growth factors controlling the thyroid gland

1991 • 88 citations

Reciprocal modulation of thyrotropin actions by P1-purinergic agonists in FRTL-5 thyroid cells. Inhibition of cAMP pathway and stimulation of phospholipase C-Ca2+ pathway

1991 • 73 citations

ATP, bradykinin, TRH and TSH activate the Ca2+-phosphatidylinositol cascade of human thyrocytes in primary culture

1991 • 69 citations

Stimulation of adenosine receptor enhances α₁ ‐adrenergic receptor‐mediated activation of phospholipase C and Ca²⁺ mobilization in a pertussis toxin‐sensitive manner in FRTL‐5 thyroid cells

1989 • 65 citations

Relationship between proliferation and cell cycle-dependent Ca2+ influx induced by a combination of thyrotropin and insulin-like growth factor-I in rat thyroid cells.

1990 • 61 citations

Extracellular ATP stimulates three different receptor-signal transduction systems in FRTL-5 thyroid cells. Activation of phospholipase C, and inhibition and activation of adenylate cyclase

1992 • 60 citations

Exogenous ATP induces a limited cell cycle progression of arterial smooth muscle cells

1993 • 59 citations

Thyroid-stimulating hormone and insulin-like growth factor-1 synergize to elevate 1,2-diacylglycerol in rat thyroid cells. Stimulation of DNA synthesis via interaction between lipid and adenylyl cyclase signal transduction systems.

1988 • 58 citations

Independent and Interactive Effects of Tetradecanoyl Phorbol Acetate on Growth and Differentiated Functions of FRTL5 Cells*

1988 • 52 citations

Calcium mobilization and cell proliferation activated by extracellular ATP in human ovarian tumour cells

1993 • 50 citations

Regulation of prostaglandin synthesis by thyrotropin, insulin or insulin-like growth factor-I, and serum in FRTL-5 rat thyroid cells.

1991 • 48 citations

Intracellular Ca²⁺Mobilization by Thyrotropin, Carbachol, and Adenosine Triphosphate in Dog Thyroid Cells*

1989 • 46 citations

Evidence for receptor‐mediated calcium entry and refilling of intracellular calcium stores in FRTL‐5 rat thyroid cells

1992 • 39 citations

A selective Ca2+calmodulin-dependent protein kinase II inhibitor, KN-62, inhibits the enhanced phosphorylation and the activation of tyrosine hydroxylase by 56 mM K+ in rat pheochromocytoma PC12h cells

1991 • 35 citations

Basic fibroblast growth factor: an autocrine mitogen of rat thyroid follicular cells?

1992 • 35 citations

Variations in the Culture Medium for FRTL5 Cells: Effects on Growth and Iodide Uptake*

1989 • 31 citations

Stimulation of aged human lung fibroblasts by extracellular ATP via suppression of arachidonate metabolism

1993 • 30 citations

Lack of correlation between the activation of the Ca2+-phosphatidylinositol cascade and the regulation of DNA synthesis in the dog thyrocyte

1992 • 28 citations

Opposite regulation of deoxyribonucleic acid synthesis and iodide uptake in rat thyroid cells by basic fibroblast growth factor: correlation with opposite regulation of c-fos and thyrotropin receptor gene expression.

1992 • 26 citations

Adenosine Has Divergent Effects on Deoxyribonucleic Acid Synthesis in FRTL5 Cells: Inhibition of Thyrotropin-Stimulated and Potentiation of Insulin-Like Growth Factor-I-Stimulated Thymidine Incorporation*

1989 • 18 citations

Importance of arachidonic acid metabolites in regulating ATP-induced calcium fluxes in thyroid FRTL-5 cells

1994 • 17 citations

Effects of phorbol ester on protein kinase C activity and effects of depletion of its activity on thyrotrophin, forskolin and 8′-bromoadenosine 3′,5′-cyclic monophosphate-induced [3H]thymidine incorporation in rat FRTL-5 cells

1993 • 14 citations

Evidence for a pertussis toxin sensitive calcium entry pathway in thyroid FRTL‐5 cells

1995 • 5 citations