Lack of correlation between the activation of the Ca2+-phosphatidylinositol cascade and the regulation of DNA synthesis in the dog thyrocyte

Signal transduction by receptors with tyrosine kinase activity

1990 • 5,528 citations

Early Signals in the Mitogenic Response

1986 • 1,498 citations

The regulation and cellular functions of phosphatidylcholine hydrolysis

1990 • 862 citations

THE PROTEIN KINASE C FAMILY: HETEROGENEITY AND ITS IMPLICATIONS

1989 • 739 citations

The cyclic AMP-mediated stimulation of cell proliferation

1989 • 464 citations

The mas oncogene encodes an angiotensin receptor

1988 • 390 citations

Ectopic Expression of the Serotonin 1c Receptor and the Triggering of Malignant Transformation

1989 • 355 citations

The Action of Thyrotropin on Thyroid Metabolism

1971 • 322 citations

Inositol lipids and cell proliferation

1987 • 315 citations

Serotonin stimulates DNA synthesis in fibroblasts acting through 5–HT1B receptors coupled to a Gi-protein

1988 • 277 citations

Acetylcholine analogue stimulates DNA synthesis in brain-derived cells via specific muscarinic receptor subtypes

1989 • 254 citations

Dissociation of protein kinase C activation from phorbol ester-induced maturation of HL-60 leukemia cells.

1985 • 218 citations

Platelet-Derived Growth Factor (PDGF)-Dependent Association of Phospholipase C-γ with the PDGF Receptor Signaling Complex

1990 • 204 citations

Insulin-like growth factor II stimulates calcium influx in competent BALB/c 3T3 cells primed with epidermal growth factor. Characteristics of calcium influx and involvement of GTP-binding protein.

1987 • 192 citations

Effect of Phospholipase C-γ Overexpression on PDGF-induced Second Messengers and Mitogenesis

1990 • 170 citations

Phosphoinositide metabolism and the control of cell proliferation

1989 • 165 citations

Single-channel and whole-cell recordings of mitogen-regulated inward currents in human cloned helper T lymphocytes

1986 • 151 citations

Mitogenesis in Response to PDGF and Bombesin Abolished by Microinjection of Antibody to PIP ₂

1988 • 146 citations

Human brain n-chimaerin cDNA encodes a novel phorbol ester receptor

1990 • 136 citations

Inhibition of Serum- and Ras-Stimulated DNA Synthesis by Antibodies to Phospholipase C

1990 • 122 citations

Antagonistic effects of thyrotropin and epidermal growth factor on thyroglobulin mRNA level in cultured thyroid cells

1985 • 118 citations

Calcium influx: an intracellular message of the mitogenic action of insulin-like growth factor-I.

1988 • 103 citations

Epidermal growth factor (EGF) stimulates inositol trisphosphate formation in cells which overexpress the EGF receptor

1987 • 99 citations

Stimulation of cell proliferation and inhibition of differentiation expression by tumor-promoting phorbol esters in dog thyroid cells in primary culture.

1986 • 96 citations

Induction of DNA synthesis in dog thyrocytes in primary culture: Synergistic effects of thyrotropin and cyclic AMP with epidermal growth factor and insulin

1987 • 95 citations

Strong and persistent activation of inositol lipid breakdown induces early mitogenic events but not Go to S phase progression in hamster fibroblasts. Comparison of thrombin and carbachol action in cells expressing M1 muscarinic acetylcholine receptors.

1990 • 89 citations

Platelet-derived growth factor (PDGF)-dependent association of phospholipase C-gamma with the PDGF receptor signaling complex.

1990 • 86 citations

REGULATION OF PROLIFERATION OF NORMAL AND NEOPLASTIC RAT LIVER CELLS BY CALCIUM AND CYCLIC AMP

1980 • 78 citations

Inhibition of bombesin-induced mitogenesis by pertussis toxin: Dissociation from phospholipase C pathway

1987 • 76 citations

Differentiation expression during proliferative activity induced through different pathways: in situ hybridization study of thyroglobulin gene expression in thyroid epithelial cells.

1990 • 72 citations

Relationship between proliferation and cell cycle-dependent Ca2+ influx induced by a combination of thyrotropin and insulin-like growth factor-I in rat thyroid cells.

1990 • 61 citations

An increase in intracellular free Ca2+ associated with serum-free growth stimulation of Swiss 3T3 fibroblasts by epidermal growth factor in the presence of bradykinin.

1988 • 60 citations

Regulation of protooncogenes c-fos and c-myc expressions by protein tyrosine kinase, protein kinase C, and cyclic AMP mitogenic pathways in dog primary thyrocytes: A positive and negative control by cyclic AMP on c-myc expression

1990 • 57 citations

Effects of pertussis toxin on growth factor-stimulated inositol phosphate formation and DNA synthesis in Swiss 3T3 cells

1988 • 53 citations

Control of the intracellular Ca²⁺‐concentration and the inositol phosphate accumulation in dog thyrocyte primary culture: Evidence for different kinetics of Ca²⁺‐phosphatidylinositol cascade activation and for involvement in the regulation of H₂O₂ production

1991 • 53 citations

Carbachol and sodium fluoride, but not TSH, stimulate the generation of inositol phosphates in the dog thyroid

1987 • 53 citations

Differential protein phosphorylation in induction of thyroid cell proliferation by thyrotropin, epidermal growth factor, or phorbol ester.

1988 • 50 citations

Intracellular Ca²⁺Mobilization by Thyrotropin, Carbachol, and Adenosine Triphosphate in Dog Thyroid Cells*

1989 • 46 citations

Epidermal growth factor stimulates formation of inositol phosphates in BALB/c/3T3 cells pretreated with cholera toxin and isobutylmethylxanthine.

1988 • 43 citations

Phorbol ester and 1,2‐diolein are not fully equivalent activators of protein kinase C in respect to phosphorylation of membrane proteins in vitro

1986 • 37 citations

Diacylglycerols, unlike phorbol esters, do not induce homologous desensitization or down-regulation of protein kinase C in Swiss 3T3 cells

1989 • 35 citations

The effects of alkylated xanthines on cyclic AMP accumulation in dog thyroid slices exposed to carbamylcholine.

1984 • 34 citations

Protein synthesis during induction of DNA replication in thyroid epithelial cells: Evidence for late markers of distinct mitogenic pathways

1989 • 31 citations

Phorbol ester-induced alteration of protein kinase C catalytic properties occurs at the membrane level and is not reproduced by physiological stimuli

1986 • 30 citations

Effects of Thyroid-Stimulating Hormone, Carbachol, Norepinephrine, and Adenosine 3′,5′-Monophosphate on Polyphosphatidylinositol Phosphate Hydrolysis in Dog Thyroid Slices*

1988 • 30 citations

Carbamylcholine, TRH, PGF2α and fluoride enhance free intracellular Ca++ and ca++ translocation in dog thyroid cells

1986 • 28 citations

Epidermal growth factor (EGF) produces inositol phosphates and increases cytoplasmic free calcium in cultured porcine thyroid cells

1988 • 26 citations

Activation of inositol phospholipid breakdown by prostaglandin F2α without any stimulation of proliferation in quiescent NIH-3T3 fibroblasts

1990 • 23 citations

Signal Transduction in Hamster Fibroblasts Overexpressing the Human EGF Receptor

1989 • 23 citations

Regulation of calcium fluxes in the thyroid

1987 • 16 citations

Phorbol myristate acetate-induced proliferation of an IL-2-dependent T-cell line: Action of PMA is independent of IL-2 and cannot be mimicked by diacylglycerols

1986 • 14 citations

Angiotensin II causes phosphatidylinositol turnover and increases 1,2-diacylglycerol mass but is not mitogenic in rat liver T51B cells

1990 • 10 citations

Carbamylcholine and thyrotropin activate distinctive pathways of protein phosphorylation in dog thyroid

1984 • 7 citations