Reciprocal modulation of thyrotropin actions by P1-purinergic agonists in FRTL-5 thyroid cells. Inhibition of cAMP pathway and stimulation of phospholipase C-Ca2+ pathway

G PROTEINS: TRANSDUCERS OF RECEPTOR-GENERATED SIGNALS

1987 • 6,374 citations

Extracellular ATP: effects, sources and fate

1986 • 1,666 citations

Culture of hormone-dependent functional epithelial cells from rat thyroids.

1980 • 959 citations

An ultrasensitive method for the simultaneous determination of cyclic AMP and cyclic GMP in small-volume samples from blood and tissue

1977 • 679 citations

Islet-activating protein, pertussis toxin: a probe for functions of the inhibitory guanine nucleotide regulatory component of adenylate cyclase

1984 • 567 citations

Polyphosphoinositide phosphodiesterase: regulation by a novel guanine nucleotide binding protein, Gp

1987 • 356 citations

INSULIN-LIKE GROWTH FACTOR-I STIMULATES THE GROWTH OF RAT THYROID CELLS IN CULTURE AND SYNERGIZES THE STIMULATION OF DNA SYNTHESIS INDUCED BY TSH AND GRAVES′-IgG

1986 • 286 citations

P2-purinergic receptors are coupled to two signal transduction systems leading to inhibition of cAMP generation and to production of inositol trisphosphate in rat hepatocytes.

1987 • 213 citations

The Relationship of Growth and Adenylate Cyclase Activity in Cultured Thyroid Cells: Separate Bioeffects of Thyrotropin

1983 • 204 citations

Thyrotropin activates both the cyclic AMP and the PIP2casades in CHO cells expressing the human cDNA of TSH receptor

1990 • 184 citations

Mitogenic Effects of Thyrotropin and Adenosine 3′,5′-Monophosphate in Differentiated Normal Human Thyroid Cellsin Vitro*

1988 • 180 citations

Dual activation by thyrotropin of the phospholipase C and cyclic AMP cascades in human thyroid

1987 • 177 citations

Association of the changes in cytosolic Ca2+ and iodide efflux induced by thyrotropin and by the stimulation of alpha 1-adrenergic receptors in cultured rat thyroid cells.

1985 • 138 citations

Effect of Thyrotropin on Iodide Efflux in FRTL-5 Cells Mediated by Ca²⁺

1984 • 134 citations

Iodination of thyroglobulin

1981 • 120 citations

Inhibition by Islet-Activating Protein, Pertussis Toxin, of P₂-Purinergic Receptor-Mediated Iodide Efflux and Phosphoinositide Turnover in FRTL-5 Cells*

1988 • 101 citations

A Permissive Role of Pertussis Toxin Substrate G-protein in P2-purinergic Stimulation of Phosphoinositide Turnover and Arachidonate Release in FRTL-5 Thyroid Cells

1989 • 99 citations

Modification of AlF4-- and Receptor-stimulated Phospholipase C Activity by G-Protein βγ Subunits

1989 • 94 citations

Evidence that Adenosine 3′,5′-Monophosphate Mediates Stimulation of Thyroid Growth in FRTL₅Cells*

1986 • 90 citations

Thyroid-stimulating hormone stimulates increases in inositol phosphates as well as cyclic AMP in the FRTL-5 rat thyroid cell line

1987 • 83 citations

Norepinephrine and Thyroid-Stimulating Hormone Induce Inositol Phosphate Accumulation in FRTL-5 Cells

1986 • 82 citations

Acute effect of thyrotropin on phosphatidylinositol degradation and transient accumulation of diacylglycerol in isolated thyroid follicles

1980 • 74 citations

Stimulation of adenosine receptor enhances α₁ ‐adrenergic receptor‐mediated activation of phospholipase C and Ca²⁺ mobilization in a pertussis toxin‐sensitive manner in FRTL‐5 thyroid cells

1989 • 65 citations

Intracellular Ca²⁺Mobilization by Thyrotropin, Carbachol, and Adenosine Triphosphate in Dog Thyroid Cells*

1989 • 46 citations

Thyrotropin and norepinephrine stimulate the metabolism of phosphoinositides in FRTL‐5 thyroid cells

1986 • 44 citations

P₂‐purinergic agonists activate phospholipase C in a guanine nucleotide‐ and Ca²⁺‐dependent manner in FRTL‐5 thyroid cell membranes

1989 • 44 citations

Origins of the sympathetic projections to rat thyroid and parathyroid glands

1986 • 43 citations

Effects of acetylcholine, TSH and other stimulators on intracellular calcium concentration in dog thyroid cells

1985 • 41 citations

Accelerated Exocytosis and H2O2 Generation in Isolated Thyroid Follicles Enhance Protein Iodination*

1988 • 40 citations

Effects of Thyroid-Stimulating Hormone, Carbachol, Norepinephrine, and Adenosine 3′,5′-Monophosphate on Polyphosphatidylinositol Phosphate Hydrolysis in Dog Thyroid Slices*

1988 • 30 citations

Carbamylcholine, TRH, PGF2α and fluoride enhance free intracellular Ca++ and ca++ translocation in dog thyroid cells

1986 • 28 citations

P2-purinergic activation of phosphoinositide turnover is potentiated by A1-receptor stimulation in thyroid cells

1991 • 27 citations

Requirement of Insulin Growth Factor I plus Hydrocortisone for the Regeneration of Thyrotropin (TSH)-Dependent Mechanism of I^-Efflux and Ca²⁺Mobilization in FRTL-5 Cells during TSH Depletion*

1989 • 25 citations

Effect of Inferior Laryngeal Nerve Section on Thyroid Function in Rats*

1988 • 24 citations

Inhibition of atrial natriuretic peptide-induced cGMP accumulation by purinergic agonists in FRTL-5 thyroid cells. Involvement of both pertussis toxin-sensitive and insensitive mechanisms.

1990 • 21 citations

Forskolin and thyrotrophin stimulation of rat FRTL-5 thyroid cell growth: the role of cyclic AMP

1987 • 19 citations

Adenosine Has Divergent Effects on Deoxyribonucleic Acid Synthesis in FRTL5 Cells: Inhibition of Thyrotropin-Stimulated and Potentiation of Insulin-Like Growth Factor-I-Stimulated Thymidine Incorporation*

1989 • 18 citations