Opposite regulation of deoxyribonucleic acid synthesis and iodide uptake in rat thyroid cells by basic fibroblast growth factor: correlation with opposite regulation of c-fos and thyrotropin receptor gene expression.

LIGAND: A versatile computerized approach for characterization of ligand-binding systems

1980 • 8,534 citations

Genomic sequencing.

1984 • 8,343 citations

Stimulation of 3T3 cells induces transcription of the c-fos proto-oncogene

1984 • 3,150 citations

Calcium and growth factor pathways of c-fos transcriptional activation require distinct upstream regulatory sequences.

1988 • 404 citations

Iodide Transport in a Continuous Line of Cultured Cells from Rat Thyroid

1984 • 342 citations

Acidic and basic fibroblast growth factors stimulate tyrosine kinase activity in vivo.

1988 • 261 citations

Cloning, chromosomal assignment, and regulation of the rat thyrotropin receptor: expression of the gene is regulated by thyrotropin, agents that increase cAMP levels, and thyroid autoantibodies.

1990 • 225 citations

Complementary DNA cloning and sequencing of rat ovarian basic fibroblast growth factor and tissue distribution study of its mRNA

1988 • 210 citations

Thyrotropin- Stimulated Iodide Transport Mediated by Adenosine 3′ 5′-Monophosphate and Dependent on Protein Synthesis

1984 • 204 citations

Receptor for acidic fibroblast growth factor is related to the tyrosine kinase encoded by the fms-like gene (FLG).

1989 • 203 citations

Characterization and cDNA cloning of phospholipase C-gamma, a major substrate for heparin-binding growth factor 1 (acidic fibroblast growth factor)-activated tyrosine kinase.

1990 • 195 citations

Factors controlling proliferation and differentiation of canine thyroid cells cultured in reduced serum conditions: effects of thyrotropin, cyclic AMP and growth factors

1984 • 186 citations

Oncogenes and growth control

1985 • 180 citations

Characterization of the Optimal Stimulatory Effects of Graves’ Monoclonal and Serum Immunoglobulin G on Adenosine 3′,5′-Monophosphate Production in FRTL-5 Thyroid Cells: A Potential Clinical Assay

1983 • 160 citations

Association of the changes in cytosolic Ca2+ and iodide efflux induced by thyrotropin and by the stimulation of alpha 1-adrenergic receptors in cultured rat thyroid cells.

1985 • 138 citations

The mitogenic signaling pathway but not the plasminogen activator-inducing pathway of basic fibroblast growth factor is mediated through protein kinase C in fetal bovine aortic endothelial cells.

1989 • 133 citations

Induction of the c- fos Oncogene by Thyrotropic Hormone in Rat Thyroid Cells in Culture

1986 • 111 citations

Basic fibroblast growth factor as a regulator of ovarian granulosa cell differentiation: a novel non-mitogenic role

1988 • 97 citations

Characterization of the 5'-flanking region of the rat thyrotropin receptor gene.

1992 • 84 citations

Regulation of thyrotropin receptor gene expression in rat FRTL-5 thyroid cells.

1992 • 82 citations

Thyroid Peroxidase: Rat cDNA Sequence, Chromosomal Localization in Mouse, and Regulation of Gene Expression by Comparison to Thyroglobulin in Rat FRTL-5 Cells

1989 • 76 citations

Basic fibroblast growth factor affects DNA synthesis and cell function and activates multiple signalling pathways in rat thyroid FRTL-5 and pituitary GH3 cells

1990 • 74 citations

Hydrogen peroxide generation and its regulation in FRTL-5 and porcine thyroid cells.

1992 • 71 citations

Relationship between proliferation and cell cycle-dependent Ca2+ influx induced by a combination of thyrotropin and insulin-like growth factor-I in rat thyroid cells.

1990 • 61 citations

Control of c-fos and c-myc Proto-Oncogene Induction in Rat Thyroid Cells in Culture

1987 • 53 citations

Regulation of prostaglandin synthesis by thyrotropin, insulin or insulin-like growth factor-I, and serum in FRTL-5 rat thyroid cells.

1991 • 48 citations

Thyroid cell growth, differentiation and function in the FRTL-5 cell line: a survey

1988 • 45 citations

Identification and Characterization of Basic Fibroblast Growth Factor in Porcine Thyroids*

1991 • 41 citations

Increases in cytosolic Ca++ down regulate thyrotropin receptor gene expression by a mechanism different from the cAMP signal

1991 • 39 citations

Basic fibroblast growth factor: an autocrine mitogen of rat thyroid follicular cells?

1992 • 35 citations

Overexpression of Phospholipase C-γ in NIH 3T3 Fibroblasts Results in Increased Phosphatidylinositol Hydrolysis in Response to Platelet-Derived Growth Factor and Basic Fibroblast Growth Factor

1990 • 34 citations

Differential Effects of Growth Factors on [3H]Thymidine Incorporation and [125I]Iodine Uptake in FRTL-5 Rat Thyroid Cells

1990 • 30 citations

Lack of correlation between the activation of the Ca2+-phosphatidylinositol cascade and the regulation of DNA synthesis in the dog thyrocyte

1992 • 28 citations

The inhibitory effect of iodide on growth of rat thyroid (FRTL-5) cells

1988 • 25 citations

Basic fibroblast growth factor is a calcium-mobilizing secretagogue in rat pancreatic acini

1991 • 19 citations

Methimazole Regulation of Thyroglobulin Biosynthesis and Gene Transcription in Rat FRTL-5 Thyroid Cells*

1991 • 15 citations

Control of the thyroid gland: Regulation of its normal function and growth

1991 • 12 citations

Transducing Systems in the Control of Human Thyroid Cell Function, Proliferation and Differentiation

1989 • 11 citations