Inhibition by Islet-Activating Protein, Pertussis Toxin, of P₂-Purinergic Receptor-Mediated Iodide Efflux and Phosphoinositide Turnover in FRTL-5 Cells*

A new generation of Ca2+ indicators with greatly improved fluorescence properties.

1985 • 21,873 citations

G PROTEINS: TRANSDUCERS OF RECEPTOR-GENERATED SIGNALS

1987 • 6,374 citations

INOSITOL TRISPHOSPHATE AND DIACYLGLYCEROL: TWO INTERACTING SECOND MESSENGERS

1987 • 3,302 citations

The role of hormone receptors and GTP-regulatory proteins in membrane transduction

1980 • 1,750 citations

Extracellular ATP: effects, sources and fate

1986 • 1,666 citations

Role of guanine nucleotide binding protein in the activation of polyphosphoinositide phosphodiesterase

1985 • 960 citations

Culture of hormone-dependent functional epithelial cells from rat thyroids.

1980 • 959 citations

A basis for distinguishing two types of purinergic receptor

1978 • 725 citations

ADP ribosylation of the specific membrane protein of C6 cells by islet-activating protein associated with modification of adenylate cyclase activity.

1982 • 600 citations

Islet-activating protein, pertussis toxin: a probe for functions of the inhibitory guanine nucleotide regulatory component of adenylate cyclase

1984 • 567 citations

Rapid breakdown of phosphatidylinositol 4-phosphate and phosphatidylinositol 4,5-bisphosphate in rat hepatocytes stimulated by vasopressin and other Ca2+-mobilizing hormones

1983 • 547 citations

Simultaneous inhibitions of inositol phospholipid breakdown, arachidonic acid release, and histamine secretion in mast cells by islet-activating protein, pertussis toxin. A possible involvement of the toxin-specific substrate in the Ca2+-mobilizing receptor-mediated biosignaling system.

1985 • 509 citations

Phospholipase A2 and phospholipase C are activated by distinct GTP-binding proteins in response to alpha 1-adrenergic stimulation in FRTL5 thyroid cells.

1986 • 424 citations

ADP-ribosylation of the specific membrane protein by islet-activating protein, pertussis toxin, associated with inhibition of a chemotactic peptide-induced arachidonate release in neutrophils. A possible role of the toxin substrate in Ca2+-mobilizing biosignaling.

1984 • 389 citations

Iodide Transport in a Continuous Line of Cultured Cells from Rat Thyroid

1984 • 342 citations

Intracellular Ca2+ mobilization by arachidonic acid. Comparison with myo-inositol 1,4,5-trisphosphate in isolated pancreatic islets.

1986 • 310 citations

Coupling of the guanine nucleotide regulatory protein to chemotactic peptide receptors in neutrophil membranes and its uncoupling by islet-activating protein, pertussis toxin. A possible role of the toxin substrate in Ca2+-mobilizing receptor-mediated signal transduction.

1985 • 281 citations

Characterization of responses of isolated rat hepatocytes to ATP and ADP.

1985 • 269 citations

Inhibition by islet-activating protein of a chemotactic peptide-induced early breakdown of inositol phospholipids and Ca2+ mobilization in guinea pig neutrophils.

1985 • 250 citations

P2-purinergic receptors are coupled to two signal transduction systems leading to inhibition of cAMP generation and to production of inositol trisphosphate in rat hepatocytes.

1987 • 213 citations

Adenosine triphosphate stimulates inositol phospholipid metabolism and prostacyclin formation in adrenal medullary endothelial cells by means of P2-purinergic receptors.

1987 • 141 citations

Association of the changes in cytosolic Ca2+ and iodide efflux induced by thyrotropin and by the stimulation of alpha 1-adrenergic receptors in cultured rat thyroid cells.

1985 • 138 citations

Effect of Thyrotropin on Iodide Efflux in FRTL-5 Cells Mediated by Ca²⁺

1984 • 134 citations

Extracellular ATP activates polyphosphoinositide breakdown and Ca2+ mobilization in Ehrlich ascites tumor cells

1986 • 125 citations

Alpha 1-adrenergic stimulation of arachidonic acid release and metabolism in a rat thyroid cell line. Mediation of cell replication by prostaglandin E2.

1986 • 89 citations

Norepinephrine and Thyrotropin Stimulation of Iodide Efflux in FRTL-5 Thyroid Cells Involves Metabolites of Arachidonic Acid and Is Associated with the Iodination of Thyroglobulin*

1987 • 57 citations

A mechanism in the control of intracellular cAMP level: the activation of a calmodulin-sensitive phosphodiesterase by a rise of intracellular free calcium

1985 • 48 citations

Thyrotropin effect on the availability of Ni regulatory protein in FRTL-5 rat thyroid cells to ADP-ribosylation by pertussis toxin

1987 • 32 citations

Purification and Subfractionation of Bovine Thyrotropin and Lutropin Using Radioimmunoassays for Evaluation of the Purification Processes1

1978 • 17 citations