Spindle Multipolarity Is Prevented by Centrosomal Clustering

Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

2001 • 9,275 citations

Centrosome aberrations: cause or consequence of cancer progression?

2002 • 725 citations

A Complex of NuMA and Cytoplasmic Dynein Is Essential for Mitotic Spindle Assembly

1996 • 565 citations

The human papillomavirus type 16 E6 and E7 oncoproteins cooperate to induce mitotic defects and genomic instability by uncoupling centrosome duplication from the cell division cycle

2000 • 483 citations

Managing the centrosome numbers game: from chaos to stability in cancer cell division

2001 • 402 citations

Dynactin Is Required for Microtubule Anchoring at Centrosomes

1999 • 354 citations

Centrosome defects can account for cellular and genetic changes that characterize prostate cancer progression.

2001 • 330 citations

Formation of Spindle Poles by Dynein/Dynactin-Dependent Transport of Numa

2000 • 323 citations

The Kinesin-Related Protein, Hset, Opposes the Activity of Eg5 and Cross-Links Microtubules in the Mammalian Mitotic Spindle

1999 • 321 citations

Opposing motor activities are required for the organization of the mammalian mitotic spindle pole.

1996 • 301 citations

Centrosome hyperamplification in human cancer: chromosome instability induced by p53 mutation and/or Mdm2 overexpression

1999 • 284 citations

Centrosome amplification and the development of cancer

2002 • 277 citations

Chromosomal instability and cytoskeletal defects in oral cancer cells

2000 • 269 citations

NuMA is required for the organization of microtubules into aster-like mitotic arrays.

1995 • 242 citations

Mitotic Spindle Poles are Organized by Structural and Motor Proteins in Addition to Centrosomes

1997 • 220 citations

Chromosomal alterations in squamous cell carcinomas of the head and neck: Window to the biology of disease

2001 • 219 citations

NuMA is required for the proper completion of mitosis.

1993 • 207 citations

Dynein light chain 1, a p21-activated kinase 1-interacting substrate, promotes cancerous phenotypes

2004 • 186 citations

High-resolution mapping of the 11q13 amplicon and identification of a gene, TAOS1 , that is amplified and overexpressed in oral cancer cells

2002 • 182 citations

Human Mps1 protein kinase is required for centrosome duplication and normal mitotic progression

2003 • 178 citations

Mitosis in a cell with multiple centrioles.

1982 • 158 citations

The good, the bad and the ugly: the practical consequences of centrosome amplification

2003 • 137 citations

Amplified Centrosomes in Breast Cancer: A Potential Indicator of Tumor Aggressiveness

2002 • 108 citations

Correlation between centrosome abnormalities and chromosomal instability in human pancreatic cancer cells

2001 • 103 citations

Mutation of the predicted p34cdc2 phosphorylation sites in numa impair the assembly of the mitotic spindle and block mitosis

1995 • 103 citations

Centriole number and process formation in established neuroblastoma cells and primary dorsal root ganglion neurones.

1982 • 48 citations

Association of anti-dynein-1 cross-reactive antigen with the mitotic spindle of mammalian cells.

1985 • 17 citations