Membrane translocation of diphtheria toxin carrying passenger protein domains

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

Diphtheria toxin entry into cells is facilitated by low pH.

1980 • 467 citations

The entry of diphtheria toxin into the mammalian cell cytoplasm: evidence for lysosomal involvement.

1980 • 372 citations

Rapid entry of nicked diphtheria toxin into cells at low pH. Characterization of the entry process and effects of low pH on the toxin molecule.

1981 • 291 citations

Entry of the toxic proteins abrin, modeccin, ricin, and diphtheria toxin into cells. I. Requirement for calcium.

1982 • 150 citations

Secondary Structure of Diphtheria Toxin and Its Fragments Interacting with acidic Liposomes Studied by Polarized Infrared Spectroscopy

1989 • 134 citations

Active-site mutations of diphtheria toxin: effects of replacing glutamic acid-148 with aspartic acid, glutamine, or serine

1990 • 91 citations

Peptides fused to the amino-terminal end of diphtheria toxin are translocated to the cytosol.

1991 • 86 citations

Low pH-induced release of diphtheria toxin A-fragment in Vero cells. Biochemical evidence for transfer to the cytosol.

1988 • 85 citations

Insertion of diphtheria toxin B-fragment into the plasma membrane at low pH. Characterization and topology of inserted regions

1991 • 78 citations

Diphtheria toxin entry: protein translocation in the reverse direction

1988 • 57 citations

Expression of a mutant, full-length form of diphtheria toxin in Escherichia coli

1987 • 50 citations

Conformation and model membrane interactions of diphtheria toxin fragment A.

1988 • 46 citations

Requirement of specific receptors for efficient translocation of diphtheria toxin A fragment across the plasma membrane.

1988 • 45 citations

Folding changes in membrane-inserted diphtheria toxin that may play important roles in its translocation

1991 • 43 citations

Membrane interactions of diphtheria toxin analyzed using in vitro synthesized mutants.

1989 • 41 citations

Energetics of diphtheria toxin membrane insertion and translocation: calorimetric characterization of the acid pH induced transition

1989 • 36 citations

Intracellular stability of diphtheria toxin fragment A in the presence and absence of anti-fragment A antibody.

1982 • 33 citations

Entry of diphtheria toxin-protein A chimeras into cells.

1991 • 28 citations

Association between diphtheria toxin A- and B-fragment and their fusion proteins

1992 • 28 citations

Formation of Active Diphtheria Toxin in vitro Based on Ligated Fragments of Cloned Mutant Genes

1989 • 15 citations