Energetics of diphtheria toxin membrane insertion and translocation: calorimetric characterization of the acid pH induced transition

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

Fluorescence probe measurement of the intralysosomal pH in living cells and the perturbation of pH by various agents.

1978 • 2,146 citations

Stability of Proteins Small Globular Proteins

1979 • 2,139 citations

ACIDIFICATION OF THE ENDOCYTIC AND EXOCYTIC PATHWAYS

1986 • 1,977 citations

Diphtheria toxin entry into cells is facilitated by low pH.

1980 • 467 citations

The entry of diphtheria toxin into the mammalian cell cytoplasm: evidence for lysosomal involvement.

1980 • 372 citations

Structure and Activity of Diphtheria Toxin

1971 • 352 citations

Statistical mechanical deconvolution of thermal transitions in macromolecules. I. Theory and application to homogeneous systems

1978 • 349 citations

Rapid entry of nicked diphtheria toxin into cells at low pH. Characterization of the entry process and effects of low pH on the toxin molecule.

1981 • 291 citations

TEMPORAL CHANGES IN <scp>P</scp>H WITHIN THE PHAGOCYTIC VACUOLE OF THE POLYMORPHONUCLEAR NEUTROPHILIC LEUKOCYTE

1973 • 241 citations

Effect of pH on the conformation of diphtheria toxin and its implications for membrane penetration

1985 • 188 citations

Entry of the toxic proteins abrin, modeccin, ricin, and diphtheria toxin into cells. I. Requirement for calcium.

1982 • 150 citations

Interaction of Fragment A from Diphtheria Toxin with Nicotinamide Adenine Dinucleotide

1974 • 147 citations

Thermodynamic Characterization of Conformational States of Biological Macromolecules using Differential Scanning Calorimetry

1978 • 145 citations

Evidence for penetration of diphtheria toxin to the cytosol through a prelysosomal membrane

1984 • 80 citations

Cell-mediated reduction of the interfragment disulfide in nicked diphtheria toxin. A new system to study toxin entry at low pH.

1987 • 75 citations

Protein and lipid structural transitions in cytochrome c oxidase-dimyristoylphosphatidylcholine reconstitutions

1985 • 60 citations

Diphtheria toxin receptor. Identification of specific diphtheria toxin-binding proteins on the surface of Vero and BS-C-1 cells.

1987 • 55 citations

Immunoprecipitation and partial characterization of diphtheria toxin-binding glycoproteins from surface of guinea pig cells.

1979 • 50 citations

Requirements for the translocation of diphtheria toxin fragment A across lipid membranes.

1985 • 50 citations

Ligand interactions of diphtheria toxin. II. Relationships between the NAD site and the P site.

1980 • 47 citations

Fluorescence characterization of the low pH-induced change in diphtheria toxin conformation: Effect of salt

1984 • 41 citations

New Form of Diphtheria Toxin

1968 • 35 citations

The complete amino acid sequence of diphtheria toxin fragment B. Correlation with its lipid-binding properties

1985 • 27 citations

Role of glycosylation in expression of functional diphtheria toxin receptors

1985 • 15 citations

Interaction of diphtheria toxin with adenylyl-(3',5')-uridine 3'-monophosphate. I. Equilibrium and kinetic measurements.

1984 • 12 citations

The amino acid sequence of fragment A, an enzymically active fragment of diphtheria toxin. II. The cyanogen bromide peptides.

1979 • 8 citations

The amino acid sequence of fragment A, an enzymically active fragment of diphtheria toxin. I. The tryptic peptides from the maleylated protein.

1979 • 8 citations