Insulin‐like growth factor binding protein 5 and type‐1 insulin‐like growth factor receptor are differentially regulated during apoptosis in cerebellar granule cells
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References (53)
Molecular Cloning: A Laboratory Manual
2001 • 133,517 citations
Molecular cloning: A laboratory manual
1990 • 85,659 citations
PTEN , a Putative Protein Tyrosine Phosphatase Gene Mutated in Human Brain, Breast, and Prostate Cancer
1997 • 4,753 citations
Insulin-Like Growth Factors and Their Binding Proteins: Biological Actions*
1995 • 4,419 citations
Cellular survival: a play in three Akts
1999 • 4,229 citations
The Tumor Suppressor, PTEN/MMAC1, Dephosphorylates the Lipid Second Messenger, Phosphatidylinositol 3,4,5-Trisphosphate
1998 • 3,053 citations
Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers
1997 • 2,746 citations
Current protocols in molecular biology
1988 • 2,473 citations
Insulin-like growth factors and their binding proteins: biological actions
1995 • 1,976 citations
Insulin-like growth factor I receptor primary structure: comparison with insulin receptor suggests structural determinants that define functional specificity.
1986 • 1,866 citations
Molecular and Cellular Aspects of the Insulin-Like Growth Factor I Receptor
1995 • 1,361 citations
The lipid phosphatase activity of PTEN is critical for its tumor supressor function
1998 • 1,180 citations
Induction of apoptosis in cerebellar granule neurons by low potassium: inhibition of death by insulin-like growth factor I and cAMP.
1993 • 886 citations
A Dissection and tissue culture manual of the nervous system
1989 • 762 citations
The Insulin-Like Growth Factors
1993 • 647 citations
Extracellular matrix contains insulin-like growth factor binding protein-5: potentiation of the effects of IGF-I.
1993 • 543 citations
Neural apoptosis
1995 • 464 citations
The role of the insulin-like growth factors in the central nervous system
1996 • 443 citations
Role of Glycogen Synthase Kinase-3β in Neuronal Apoptosis Induced by Trophic Withdrawal
2000 • 440 citations
Role of Ca2+ channels in the ability of membrane depolarization to prevent neuronal death induced by trophic-factor deprivation: evidence that levels of internal Ca2+ determine nerve growth factor dependence of sympathetic ganglion cells.
1989 • 405 citations
Apoptosis in cerebellar granule cells is blocked by high KCl, forskolin, and IGF-1 through distinct mechanisms of action: the involvement of intracellular calcium and RNA synthesis
1995 • 403 citations
Role of insulin-like growth factor binding proteins in controlling IGF actions
1998 • 401 citations
Tumor Suppressor PTEN Inhibits Integrin- and Growth Factor–mediated Mitogen-activated Protein (MAP) Kinase Signaling Pathways
1998 • 336 citations
Identification of five different insulin-like growth factor binding proteins (IGFBPs) from adult rat serum and molecular cloning of a novel IGFBP-5 in rat and human
1991 • 313 citations
Identification of the forms of insulin-like growth factor-binding proteins produced by human fibroblasts and the mechanisms that regulate their secretion.
1992 • 295 citations
Insulin-Like Growth Factor and Potassium Depolarization Maintain Neuronal Survival by Distinct Pathways: Possible Involvement of PI 3-Kinase in IGF-1 Signaling
1997 • 294 citations
Inhibition of Phosphatidylinositol 3-Kinase Activity Blocks Depolarization- and Insulin-like Growth Factor I-mediated Survival of Cerebellar Granule Cells
1997 • 246 citations
Characterization of recombinant human insulin-like growth factor binding proteins 4, 5, and 6 produced in yeast.
1992 • 183 citations
Autocrine—paracrine Regulation of Hippocampal Neuron Survival by IGF‐1 and the Neurotrophins BDNF, NT‐3 and NT‐4
1996 • 182 citations
Discussion
1997 • 179 citations
Serum and depolarizing agents cause acute neurotoxicity in cultured cerebellar granule cells: role of the glutamate receptor responsive to N-methyl-D-aspartate.
1990 • 176 citations
IGF binding proteins and their functions
1993 • 156 citations
Removal of serum from primary cultures of cerebellar granule neurons induces oxidative stress and DNA fragmentation: Protection with antioxidants and glutamate receptor antagonists
1996 • 139 citations
Correlation between insulin-like growth factor (IGF)-binding protein 5 and IGF-I gene expression during brain development
1993 • 138 citations
The Insulin-Like Growth Factor-I Receptor Signaling Pathways Are Important for Tumorigenesis and Inhibition of Apoptosis
1997 • 137 citations
Differential Regulation of Insulin-like Growth Factor-I (IGF-I) Receptor Gene Expression by IGF-I and Basic Fibroblastic Growth Factor
1997 • 100 citations
The IGF system : molecular biology, physiology, and clinical applications
1999 • 99 citations
Insulin and insulinlike growth factor 1 (IGF-1) receptors during central nervous system development: expression of two immunologically distinct IGF-1 receptor beta subunits.
1989 • 84 citations
Biochemical and Temporal Analysis of Events Associated with Apoptosis Induced by Lowering the Extracellular Potassium Concentration in Mouse Cerebellar Granule Neurons
1997 • 83 citations
Insulin-like growth factor I (IGF-I) is a critical trophic factor for developing cerebellar granule cells
1997 • 73 citations
Androgen Receptor Up-Regulates Insulin-Like Growth Factor Binding Protein-5 (IGFBP-5) Expression in a Human Prostate Cancer Xenograft*
1999 • 73 citations
Insulin-Like Growth Factor I (IGF-I) Regulates IGF Binding Protein-5 Gene Expression in the Brain*
1998 • 64 citations
Involvement of phosphatidylinositol-3 kinase in prevention of low K+-induced apoptosis of cerebellar granule neurons
1997 • 63 citations
Differential expression of insulin-like growth factor binding proteins (IGFBP) 4 and 5 mRNA in the rat brain after transient hypoxic-ischemic injury
1993 • 62 citations
Regulation of PTEN expression in neuronal apoptosis
1999 • 36 citations
The IGF System
1999 • 34 citations
Immunohistochemical localization of insulin-like growth factor binding protein-5 in the developing rat nervous system
1996 • 33 citations
Organization, Expression, and Chromosomal Location of the Mouse Insulin-like Growth Factor Binding Protein 5 Gene
1994 • 27 citations
Androgen Receptor Up-Regulates Insulin-Like Growth Factor Binding Protein-5 (IGFBP-5) Expression in a Human Prostate Cancer Xenograft
1999 • 25 citations
Distinct β-subunits are present in hybrid insulin-like-growth-factor-1 receptors in the central nervous system
1993 • 24 citations
Altered IGFBP5 gene expression in the cerebellar external germinal layer of weaver mutant mice
1995 • 21 citations
Expression of Seizure-Related PTZ-17 Is Induced by Potassium Deprivation in Cerebellar Granule Cells
1998 • 10 citations
A differential display protocol to identify differentially expressed mRNAs in potassium-deprived cerebellar granule cells
2000 • 8 citations