Insulin-like growth factor I receptor primary structure: comparison with insulin receptor suggests structural determinants that define functional specificity.

A simple method for displaying the hydropathic character of a protein

1982 • 22,471 citations

A method for the quantitative recovery of protein in dilute solution in the presence of detergents and lipids

1984 • 3,959 citations

RNA molecular weight determinations by gel electrophoresis under denaturing conditions, a critical reexamination

1977 • 3,548 citations

Compilation and analysis of sequences upstream from the translational start site in eukaryotic mRNAs

1984 • 3,334 citations

Human epidermal growth factor receptor cDNA sequence and aberrant expression of the amplified gene in A431 epidermoid carcinoma cells

1984 • 2,762 citations

DNA cloning : a practical approach

1985 • 2,302 citations

Human insulin receptor and its relationship to the tyrosine kinase family of oncogenes

1985 • 2,257 citations

Tyrosine Kinase Receptor with Extensive Homology to EGF Receptor Shares Chromosomal Location with neu Oncogene

1985 • 1,804 citations

The c-fms proto-oncogene product is related to the receptor for the mononuclear phagocyte growth factor, CSF 1

1985 • 1,590 citations

The human insulin receptor cDNA: The structural basis for hormone-activated transmembrane signalling

1985 • 1,485 citations

A Method for Isolation of Intact, Translationally Active Ribonucleic Acid

1983 • 1,469 citations

The human LDL receptor: A cysteine-rich protein with multiple Alu sequences in its mRNA

1984 • 1,386 citations

Actions of Insulin-Like Growth Factors

1985 • 1,141 citations

[17] Isolation of microgram quantities of proteins from polyacrylamide gels for amino acid sequence analysis

1983 • 1,115 citations

Localization of single copy DNA sequences on G-banded human chromosomes by in situ hybridization

1981 • 836 citations

The subunit structures of two distinct receptors for insulin-like growth factors I and II and their relationship to the insulin receptor.

1982 • 709 citations

Efficient transcription of RNA into DNA by avian sarcoma virus polymerase

1976 • 688 citations

Development of hormone receptors and hormonal responsiveness in vitro. Insulin receptors and insulin sensitivity in the preadipocyte and adipocyte forms of 3T3-L1 cells.

1978 • 678 citations

Protein kinase C phosphorylation of the EGF receptor at a threonine residue close to the cytoplasmic face of the plasma membrane

1984 • 656 citations

The Nature and Regulation of the Receptors for Insulin-Like Growth Factors

1985 • 639 citations

Structural alteration of viral homologue of receptor proto-oncogene fms at carboxyl terminus

1986 • 478 citations

Monoclonal antibodies to receptors for insulin and somatomedin-C.

1983 • 423 citations

Somatomedin-C stimulates the phosphorylation of the beta-subunit of its own receptor.

1983 • 395 citations

Phorbol esters stimulate the phosphorylation of receptors for insulin and somatomedin C.

1983 • 291 citations

Purification of insulin receptor with full binding activity.

1983 • 273 citations

Monoclonal antibody to the type I insulin-like growth factor (IGF-I) receptor blocks IGF-I receptor-mediated DNA synthesis: clarification of the mitogenic mechanisms of IGF-I and insulin in human skin fibroblasts.

1986 • 269 citations

Phorbol esters modulate insulin receptor phosphorylation and insulin action in cultured hepatoma cells.

1984 • 260 citations

Stimulation of tyrosine-specific phosphorylation in vitro by insulin-like growth factor I

1983 • 254 citations

Protein kinase C phosphorylates pp60src at a novel site

1985 • 243 citations

Role of glycosylation in the processing of newly translated insulin proreceptor in 3T3-L1 adipocytes.

1984 • 207 citations

Structural similarities between human receptors for somatomedin C and insulin: analysis by affinity labeling

1981 • 187 citations

Isolation of the human insulin-like growth factor I gene using a single synthetic DNA probe.

1984 • 177 citations

Nucleotide sequence of avian sarcoma virus UR2 and comparison of its transforming gene with other members of the tyrosine protein kinase oncogene family

1985 • 167 citations

Chromosomal sublocalization of human c-myb and c-fes cellular onc genes

1983 • 154 citations

Gene for Human Insulin Receptor: Localization to Site on Chromosome 19 Involved in Pre-B-Cell Leukemia

1985 • 150 citations

Regulation of Insulin Receptors and Insulin Responsiveness in 3T3-L1 Fatty Fibroblasts

1979 • 147 citations

Monensin blocks the maturation of receptors for insulin and somatomedin C: Identification of receptor precursors

1983 • 147 citations

Somatomedin receptor of human placenta: solubilization, photolabeling, partial purification, and comparison with insulin receptor.

1981 • 136 citations

Synthesis of oligonucleotides on cellulose by a phosphotriester method

1980 • 113 citations

The pronatriodilatin gene is located on the distal short arm of human chromosome 1 and on mouse chromosome 4.

1985 • 111 citations

Phosphorylation of receptors for insulin and insulin-like growth factor I. Effects of hormones and phorbol esters.

1986 • 102 citations

Advances in Human Genetics 14

1985 • 90 citations

Insulin-like growth factor-I (IGF-I) stimulates tyrosine kinase activity in purified receptors from a rat liver cell line

1984 • 89 citations

A cytochrome P‐450 gene family mapped to human chromosome 19

1985 • 80 citations

Receptor aggregation is necessary for activation of the soluble insulin receptor kinase.

1986 • 76 citations

Assignment of the human 2,3,7,8-tetrachlorodibenzo-p-dioxin-inducible cytochrome P₁-450 gene to chromosome 15

1985 • 68 citations

Purification of insulin-like growth factor I receptor from human placental membranes.

1986 • 51 citations

Urea treatment allows dithiothreitol to release the binding subunit of the insulin receptor from the cell membrane: Implications for the structural organization of the insulin receptor

1985 • 26 citations

Expression of ?-d-mannosidase in man-hamster somatic cell hybrids

1977 • 18 citations

Requirement of human chromosomes 19, 6 and possibly 3 for infection of hamster × human hybrid cells with baboon M7 type C virus

1979 • 18 citations

Assignment of cytoplasmic α-mannosidase (<i>MAN<sub>A</sub></i>) and confirmation of mitochondrial isocitrate dehydrogenase (<i>IDH<sub>A</sub></i>) to the q11→qter region of chromosome 15 in man

1978 • 17 citations

Confirmation of the synteny of the human genes for mannose phosphate isomerase and pyruvate kinase and of their assignment to chromosome 15

1975 • 17 citations