Induction of apoptosis in cerebellar granule neurons by low potassium: inhibition of death by insulin-like growth factor I and cAMP.

Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death

1990 • 3,817 citations

Social controls on cell survival and cell death

1992 • 2,641 citations

Mechanisms and Functions of Cell Death

1991 • 2,061 citations

Trophic factors and neuronal survival

1989 • 1,631 citations

Neurotrophin-3: a Neurotrophic Factor Related to NGF and BDNF

1990 • 1,261 citations

NT-3, BDNF, and NGF in the developing rat nervous system: Parallel as well as reciprocal patterns of expression

1990 • 1,238 citations

trkC, a new member of the trk family of tyrosine protein kinases, is a receptor for neurotrophin-3

1991 • 1,078 citations

An improved method to determine cell viability by simultaneous staining with fluorescein diacetate-propidium iodide.

1985 • 1,068 citations

Inhibitors of protein synthesis and RNA synthesis prevent neuronal death caused by nerve growth factor deprivation.

1988 • 909 citations

The nerve growth factor: thirty-five years later.

1987 • 720 citations

Selective and nonselective stimulation of central cholinergic and dopaminergic development in vitro by nerve growth factor, basic fibroblast growth factor, epidermal growth factor, insulin and the insulin-like growth factors I and II

1990 • 529 citations

Autoradiographic localization and depolarization-induced release of acidic amino acids in differentiating cerebellar granule cell cultures

1984 • 408 citations

Role of Ca2+ channels in the ability of membrane depolarization to prevent neuronal death induced by trophic-factor deprivation: evidence that levels of internal Ca2+ determine nerve growth factor dependence of sympathetic ganglion cells.

1989 • 405 citations

Localization of FGF receptor mRNA in the adult rat central nervous system by in situ hybridization

1990 • 387 citations

Suppression of programmed neuronal death by sustained elevation of cytoplasmic calcium

1992 • 363 citations

PDGF A-chain gene is expressed by mammalian neurons during development and in maturity

1991 • 360 citations

Aurintricarboxylic acid rescues PC12 cells and sympathetic neurons from cell death caused by nerve growth factor deprivation: correlation with suppression of endonuclease activity.

1991 • 359 citations

Multiple agents rescue PC12 cells from serum-free cell death by translation- and transcription-independent mechanisms

1991 • 337 citations

Basic fibroblast growth factor promotes the survival and development of mesencephalic neurons in culture

1989 • 318 citations

cAMP analogs promote survival and neurite outgrowth in cultures of rat sympathetic and sensory neurons independently of nerve growth factor.

1988 • 312 citations

Transient IGF-I gene expression during the maturation of functionally related central projection neurons

1991 • 287 citations

Receptors for Insulin-like Growth Factors I and II: Autoradiographic Localization in Rat Brain and Comparison to Receptors for Insulin*

1988 • 252 citations

The effect of potassium on neuronal differentiation in cultures of dissociated newborn rat cerebellum

1972 • 244 citations

Changes in neurotrophin responsiveness during the development of cerebellar granule neurons

1992 • 240 citations

Noise and single channels activated by excitatory amino acids in rat cerebellar granule neurones.

1988 • 223 citations

The Death Programme in Cultured Sympathetic Neurones Can Be Suppressed at the Posttranslational Level by Nerve Growth Factor, Cyclic AMP, and Depolarization

1991 • 202 citations

Serum and depolarizing agents cause acute neurotoxicity in cultured cerebellar granule cells: role of the glutamate receptor responsive to N-methyl-D-aspartate.

1990 • 176 citations

Glutamate‐Induced Neuronal Death Is Not a Programmed Cell Death in Cerebellar Culture

1993 • 160 citations

Localization of insulin-like growth factor-1 mRNA in murine central nervous system during postnatal development

1991 • 144 citations

Developmental and regional expression of basic fibroblast growth factor mRNA in the rat central nervous system

1990 • 115 citations

Differing expression of insulin‐like growth factor I in the developing and in the adult rat cerebellum

1988 • 110 citations

Elevated potassium induces morphological differentiation of dorsal root ganglionic neurons in dissociated cell culture

1980 • 105 citations

Immunocytochemical and electrophysiological differentiation of rat cerebellar granule cells in explant cultures

1987 • 86 citations

Calcium-dependent glutamate cytotoxicity in a neuronal cell line

1988 • 85 citations

Rapid turnover of endogenous endonuclease activity in thymocytes: Effects of inhibitors of macromolecular synthesis

1990 • 60 citations

Effect of depolarizing agents on choline acetyltransferase and acetylcholinesterase activities in primary cell cultures of spinal cord

1983 • 55 citations

Recombinant human insulin-like growth factor I exerts a trophic action and confers glutamate sensitivity on glutamate-resistant cerebellar granule cells.

1993 • 46 citations

Modulation of Non‐N‐Methyl‐D‐Aspartate Receptors in Cultured Cerebellar Granule Cells

1990 • 45 citations

SGP2, ubiquitin, 14K lectin and RP8 mRNAs are not induced in neuronal apoptosis

1993 • 27 citations

Treatment with excitatory amino acids or high K+ and NMDA receptors in cerebellar granule cells

1992 • 19 citations