Protective Immune Responses Induced by Vaccination with an Expression Genomic Library ofLeishmania major

Genetic immunization is a simple method for eliciting an immune response

1992 • 1,505 citations

DNA VACCINES

1997 • 977 citations

CpG oligodeoxynucleotides trigger protective and curative Th1 responses in lethal murine leishmaniasis.

1998 • 457 citations

Gene vaccination: plasmid DNA is more than just a blueprint

1998 • 359 citations

Vaccination with DNA Encoding the Immunodominant LACK Parasite Antigen Confers Protective Immunity to Mice Infected with Leishmania major

1997 • 359 citations

Cutting Edge: CpG Oligodeoxynucleotides Trigger Protective and Curative Th1 Responses in Lethal Murine Leishmaniasis

1998 • 349 citations

Immunology of Leishmaniasis

1993 • 337 citations

Protection against mycoplasma infection using expression-library immunization

1995 • 296 citations

Resistance to Leishmania major Induced by Tolerance to a Single Antigen

1996 • 258 citations

Effective immunization against cutaneous leishmaniasis with defined membrane antigens reconstituted into liposomes.

1988 • 236 citations

Oral Salmonella typhimurium (AroA-) vaccine expressing a major leishmanial surface protein (gp63) preferentially induces T helper 1 cells and protective immunity against leishmaniasis.

1990 • 188 citations

Protection against leishmaniasis by injection of DNA encoding a major surface glycoprotein, gp63, of L. major.

1995 • 171 citations

Human and Murine Immune Responses to a NovelLeishmania majorRecombinant Protein Encoded by Members of a Multicopy Gene Family

1998 • 170 citations

A recombinant Leishmania antigen that stimulates human peripheral blood mononuclear cells to express a Th1-type cytokine profile and to produce interleukin 12.

1995 • 157 citations

LeIF: A Recombinant Leishmania Protein That Induces an IL-12-Mediated Th1 Cytokine Profile

1998 • 146 citations

A Qualitative Progression in HIV Type 1 Glycoprotein 120-Specific Cytotoxic Cellular and Humoral Immune Responses in Mice Receiving a DNA-Based Glycoprotein 120 Vaccine

1994 • 143 citations

Membrane glycoprotein M-2 protects against Leishmania amazonensis infection

1988 • 133 citations

Leishmania pifanoi amastigote antigens protect mice against cutaneous leishmaniasis

1995 • 121 citations

Protective vaccination with promastigote surface antigen 2 from Leishmania major is mediated by a TH1 type of immune response

1995 • 107 citations

Septic Arthritis Following Staphylococcus aureus Infection in Mice Lacking Inducible Nitric Oxide Synthase

1998 • 106 citations

Interleukin-4 stimulates cGMP production by IFN-gamma-activated human monocytes. Involvement of the nitric oxide synthase pathway

1994 • 100 citations

Vaccine efficacy of Salmonella strains expressing glycoprotein 63 with different promoters

1997 • 88 citations

Prophylactic immunization against experimental leishmaniasis. III. Protection against fatal Leishmania tropica infection induced by irradiated promastigotes involves Lyt-1+2- T cells that do not mediate cutaneous DTH.

1984 • 79 citations

Stimulation of human T lymphocytes by Leishmania lipophosphoglycan-associated proteins.

1992 • 65 citations

Isolation of DNA and RNA from Leishmania

2003 • 37 citations

ELI's coming: expression library immunization and vaccine antigen discovery

1996 • 15 citations