Vaccine efficacy of Salmonella strains expressing glycoprotein 63 with different promoters

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Cleavage of structural proteins during the assemble of the head of bacterio-phage T4

1970 • 5,738 citations

Advanced bacterial genetics

1980 • 2,388 citations

Reciprocal expression of interferon gamma or interleukin 4 during the resolution or progression of murine leishmaniasis. Evidence for expansion of distinct helper T cell subsets.

1989 • 1,462 citations

The Regulation of Immunity to Leishmania Major

1995 • 1,265 citations

Vectors bearing a hybrid trp-lac promoter useful for regulated expression of cloned genes in Escherichia coli

1983 • 810 citations

Transformation of Salmonella typhimurium by Plasmid Deoxyribonucleic Acid

1974 • 777 citations

Plasmid vectors for high-efficiency expression controlled by the promoter of coliphage lambda

1981 • 664 citations

R. W. Davis, D. Botstein and J. R. Roth, A Manual for Genetic Engineering, Advanced Bacterial Genetics. 251 S., 15 Abb. Cold Spring Harbor 1980. Cold Spring Harbor Laboratory. $ 28.20

1981 • 434 citations

Construction of an ASD+ Expression-Cloning Vector: Stable Maintenance and High Level Expression of Cloned Genes in a Salmonella Vaccine Strain

1988 • 342 citations

Immunology of Leishmaniasis

1993 • 337 citations

Salmonella typhimurium LT2 strains which are r- m+ for all three chromosomally located systems of DNA restriction and modification

1983 • 294 citations

Characterization of aromatic- and purine-dependent Salmonella typhimurium: attention, persistence, and ability to induce protective immunity in BALB/c mice

1988 • 290 citations

Use of the nirB Promoter to Direct the Stable Expression of Heterologous Antigens in Salmonella Oral Vaccine Strains: Development of a Single–Dose Oral Tetanus Vaccine

1992 • 233 citations

Superior efficacy of secreted over somatic antigen display in recombinant Salmonella vaccine induced protection against listeriosis.

1996 • 219 citations

Oral Salmonella typhimurium (AroA-) vaccine expressing a major leishmanial surface protein (gp63) preferentially induces T helper 1 cells and protective immunity against leishmaniasis.

1990 • 188 citations

Tumour necrosis factor (TNF alpha) in leishmaniasis. I. TNF alpha mediates host protection against cutaneous leishmaniasis.

1990 • 168 citations

Host Resistance to the Khartoum Strain of Leishmania donovani

1958 • 149 citations

Osmolarity and growth phase overlap in regulation of Salmonella typhi adherence to and invasion of human intestinal cells

1993 • 136 citations

Genes encoding the major surface glycoprotein in Leishmania are tandemly linked at a single chromosomal locus and are constitutively transcribed

1989 • 131 citations

Salmonella typhimuriumaroA mutants as carriers of the Escherichia coli heat-labile enterotoxin B subunit to the murine secretory and systemic immune systems

1987 • 127 citations

Characterization of a Salmonella typhimurium aro vaccine strain expressing the P.69 antigen of Bordetella pertussis

1992 • 110 citations

A chromosomal integration system for stabilization of heterologous genes in Salmonella based vaccine strains

1988 • 109 citations

Location and sequence of the promoter of the gene for the NADH-dependent nitrite reductase of Escherichia coli and its regulation by oxygen, the Fnr protein and nitrite

1987 • 108 citations

Osmotic induction of gene osmC expression in Escherichia coli K12

1991 • 107 citations

An Escherichia coli hemolysin transport system-based vector for the export of polypeptides: Export of shiga-like toxin IIeB subunit by Salmonella typhimurium aroA

1996 • 93 citations

Protection against Leishmania major infection in genetically susceptible BALB/c mice by gp63 delivered orally in attenuated Salmonella typhimurium (AroA- AroD-).

1995 • 85 citations

Bacillus anthracis protective antigen, expressed in Salmonella typhimurium SL 3261, affords protection against anthrax spore challenge

1994 • 80 citations

Prophylactic immunization against experimental leishmaniasis. III. Protection against fatal Leishmania tropica infection induced by irradiated promastigotes involves Lyt-1+2- T cells that do not mediate cutaneous DTH.

1984 • 79 citations

Stable expression of foreign antigens from the chromosome of Salmonella typhimurium vaccine strains

1990 • 79 citations

Construction, expression, and immunogenicity of the Schistosoma mansoni P28 glutathione S-transferase as a genetic fusion to tetanus toxin fragment C in a live Aro attenuated vaccine strain of Salmonella.

1994 • 78 citations

Macrophage-inducible expression of a model antigen in Salmonella typhimurium enhances immunogenicity.

1995 • 73 citations

High level heterologous expression inE.coliusing the anaerobically-activatednirBpromoter

1991 • 69 citations

A Salmonella typhimurium htrA live vaccine expressing multiple copies of a peptide comprising amino acids 8–23 of herpes simplex virus glycoprotein D as a genetic fusion to tetanus toxin fragment C protects mice from herpes simplex virus infection

1996 • 61 citations

Construction, expression, and immunogenicity of multiple tandem copies of the Schistosoma mansoni peptide 115-131 of the P28 glutathione S-transferase expressed as C-terminal fusions to tetanus toxin fragment C in a live aro-attenuated vaccine strain of Salmonella.

1994 • 58 citations

Cytochrome c552 and nitrite reduction in Escherichia coli

1968 • 56 citations

Expression of LacZ from thehtrA, nirBandgroEpromoters in aSalmonellavaccine strain: Influence of growth in mammalian cells

1995 • 54 citations

Distinctive cellular immunity in genetically susceptible BALB/c mice recovered from Leishmania major infection or after subcutaneous immunization with killed parasites.

1987 • 45 citations

Differential induction of carrier antigen-specific immunity by Salmonella typhimurium live-vaccine strains after single mucosal or intravenous immunization of BALB/c mice

1995 • 42 citations

Acquisition of cell-mediated immunity to Leishmania. I. Primary T-cell activation detected by IL-2 receptor expression.

1987 • 28 citations

Construction and evaluation of an expression vector allowing the stable expression of foreign antigens in a Salmonella typhimurium vaccine strain

1994 • 25 citations

Studies of the anaerobically induced promoter pnirB and the improved expression of bacterial antigens

1995 • 14 citations

Modification of the bacteriophage vector M13mp2: introduction of new restriction sites for cloning

1981 • 13 citations