A Qualitative Progression in HIV Type 1 Glycoprotein 120-Specific Cytotoxic Cellular and Humoral Immune Responses in Mice Receiving a DNA-Based Glycoprotein 120 Vaccine

Heterologous Protection Against Influenza by Injection of DNA Encoding a Viral Protein

1993 • 2,330 citations

Genetic immunization is a simple method for eliciting an immune response

1992 • 1,505 citations

A TH1→TH2 switch is a critical step in the etiology of HIV infection

1993 • 1,403 citations

DNA vaccines: protective immunizations by parenteral, mucosal, and gene-gun inoculations.

1993 • 1,122 citations

Differing Lymphokine Profiles of Functional Subsets of Human CD4 and CD8 T Cell Clones

1991 • 1,027 citations

Protective Effects of a Live Attenuated SIV Vaccine with a Deletion in the nef Gene

1992 • 1,025 citations

Assignment of intrachain disulfide bonds and characterization of potential glycosylation sites of the type 1 recombinant human immunodeficiency virus envelope glycoprotein (gp120) expressed in Chinese hamster ovary cells.

1990 • 975 citations

Induction of TH1 and TH2 responses: a key role for the ‘natural’ immune response?

1992 • 794 citations

Gene inoculation generates immune responses against human immunodeficiency virus type 1.

1993 • 655 citations

Cure of murine leishmaniasis with anti-interleukin 4 monoclonal antibody. Evidence for a T cell-dependent, interferon gamma-independent mechanism.

1990 • 629 citations

In vivo and in vitro gene transfer to mammalian somatic cells by particle bombardment.

1990 • 603 citations

Protection of chimpanzees from infection by HIV-1 after vaccination with recombinant glycoprotein gp120 but not gp160

1990 • 593 citations

Establishment of Stable, Cell-Mediated Immunity that Makes "Susceptible" Mice Resistant to Leishmania major

1992 • 503 citations

Changes in interleukin-2 and interleukin-4 production in asymptomatic, human immunodeficiency virus-seropositive individuals.

1993 • 484 citations

Protection against a lethal influenza virus challenge by immunization with a haemagglutinin-expressing plasmid DNA

1993 • 432 citations

An immunodominant epitope of the human immunodeficiency virus envelope glycoprotein gp160 recognized by class I major histocompatibility complex molecule-restricted murine cytotoxic T lymphocytes.

1988 • 417 citations

Restoration of HIV-Specific Cell-Mediated Immune Responses by Interleukin-12 in Vitro

1993 • 397 citations

Cell-Mediated Immune Response to Human Immunodeficiency Virus (HIV) Type 1 in Seronegative Homosexual Men with Recent Sexual Exposure to HIV-1

1992 • 392 citations

The skin immune system: progress in cutaneous biology

1993 • 387 citations

Bovine herpesvirus 1: immune responses in mice and cattle injected with plasmid DNA

1993 • 344 citations

Protection of Macaques Against SIV Infection by Subunit Vaccines of SIV Envelope Glycoprotein gp160

1992 • 340 citations

Heterologous and Homologous Protection Against Influenza A by DNA Vaccination: Optimization of DNA Vectors

1993 • 267 citations

Protection Against Vaginal SIV Transmission with Microencapsulated Vaccine

1993 • 265 citations

CD8+ T cells can be primed in vitro to produce IL-4.

1992 • 214 citations

Examination of Parameters Affecting the Elicitation of Humoral Immune Responses by Particle Bombardment-Mediated Genetic Immunization

1993 • 188 citations

Systemic immunological effects of cytokine genes injected into skeletal muscle.

1993 • 174 citations

DNA Inoculation Induces Neutralizing Immune Responses Against Human Immunodeficiency Virus Type 1 in Mice and Nonhuman Primates

1993 • 166 citations

Long-Term Anti-Nucleoprotein Cellular and Humoral Immunity Is Induced by Intramuscular Injection of Plasmid DNA Containing NP Gene

1993 • 150 citations

Nuclear factor 1 interacts with five DNA elements in the promoter region of the human cytomegalovirus major immediate early gene.

1986 • 137 citations

Use of DNA Encoding Influenza Hemagglutinin as an Avian Influenza Vaccine

1993 • 125 citations

Soybean genetic engineering - commercial production of transgenic plants

1990 • 123 citations

A human cell factor is essential for HIV-1 Rev action.

1990 • 120 citations

Resistance of Mice Deficient in IL-4 to Retrovirus-Induced Immunodeficiency Syndrome (MAIDS)

1993 • 112 citations

The Ability of Certain SIV Vaccines to Provoke Reactions Against Normal Cells

1992 • 87 citations

Studies on the Specificity of the Vaccine Effect Elicited by Inactivated Simian Immunodeficiency Virus

1993 • 77 citations

Lymphocytes from Some Long-Term Seronegative Heterosexual Partners of HIV-Infected Individuals Proliferate in Response to HIV Antigens

1992 • 61 citations

Induction of antibodies to a kappa V region by gene immunization.

1993 • 56 citations

Detection of Anti-Human Cell Antibodies in Sera from Macaques Immunized with Whole Inactivated Virus

1992 • 55 citations

Cytokine regulation of T-cell function: potential for therapeutic intervention

1993 • 47 citations

Protection of monkeys by a split vaccine against SIVmac depends upon biological properties of the challenge virus

1993 • 43 citations

Dendritic cells of the skin.

1990 • 35 citations

Dendritic Cells of the Skin

1990 • 26 citations

Protection of Cynomolgus Macaques (Macaca fascicularis) Against Infection with the Human Immunodeficiency Virus Type 2 Strain ben (HIV-2ben) by Immunization with the Virion-Derived Envelope Glycoprotein gp130

1993 • 18 citations

Prevention of transmission of simian immunodeficiency virus from vaccinated macaques that developed transient virus infection following challenge

1993 • 15 citations