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1999 • 1,273 citations

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1977 • 567 citations

UmuD′ ₂ C is an error-prone DNA polymerase, Escherichia coli pol V

1999 • 524 citations

The dinB Gene Encodes a Novel E. coli DNA Polymerase, DNA Pol IV, Involved in Mutagenesis

1999 • 469 citations

Roles of E. coli DNA polymerases IV and V in lesion-targeted and untargeted SOS mutagenesis

2000 • 444 citations

Xeroderma pigmentosum variant (XP-V) correcting protein from HeLa cells has a thymine dimer bypass DNA polymerase activity

1999 • 425 citations

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1995 • 422 citations

Fidelity of Human DNA Polymerase η

2000 • 395 citations

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1996 • 383 citations

The Mutagenesis Protein UmuC Is a DNA Polymerase Activated by UmuD′, RecA, and SSB and Is Specialized for Translesion Replication

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The Saccharomyces cerevisiae RAD30 Gene, a Homologue of Escherichia coli dinB and umuC, Is DNA Damage Inducible and Functions in a Novel Error-Free Postreplication Repair Mechanism

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Error-prone bypass of certain DNA lesions by the human DNA polymerase κ

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DNA polymerase mu (Pol micro), homologous to TdT, could act as a DNA mutator in eukaryotic cells

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A plethora of lesion-replicating DNA polymerases

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Uvm mutants of Escherichia coli K 12 deficient in UV mutagenesis

1978 • 233 citations

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1995 • 225 citations

Targeting of non-lg sequences in place of the V segment by somatic hyper mutation

1995 • 223 citations

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2000 • 220 citations

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1998 • 202 citations

Human and mouse homologs of Escherichia coli DinB (DNA polymerase IV), members of the UmuC/DinB superfamily

1999 • 189 citations

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1996 • 184 citations

Novel Human and Mouse Homologs of Saccharomyces cerevisiae DNA Polymerase η

1999 • 183 citations

The human DINB1 gene encodes the DNA polymerase Polθ

2000 • 182 citations

Fidelity and Processivity of Saccharomyces cerevisiae DNA Polymerase η

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1999 • 176 citations

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1996 • 175 citations

Accuracy of thymine-thymine dimer bypass by Saccharomyces cerevisiae DNA polymerase eta

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1993 • 158 citations

Specificity of DNA Lesion Bypass by the Yeast DNA Polymerase η

2000 • 145 citations

Mutation enhancement by DINB1, a mammalian homologue of the Escherichia coli mutagenesis protein DinB

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Hypermutation of Immunoglobulin Genes in Memory B Cells of DNA Repair–deficient Mice

1998 • 116 citations

Highly mutagenic replication by DNA polymerase V (UmuC) provides a mechanistic basis for SOS untargeted mutagenesis

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Genetic requirements and mutational specificity of the Escherichia coli SOS mutator activity

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Construction of a umuDC operon substitution mutation in Escherichia coli

1992 • 113 citations

Mutational pattern of the nurse shark antigen receptor gene (NAR) is similar to that of mammalian Ig genes and to spontaneous mutations in evolution: the translesion synthesis model of somatic hypermutation

1999 • 106 citations

Altered spectra of hypermutation in antibodies from mice deficient for the DNA mismatch repair protein PMS2

1998 • 105 citations

Requirement of DNA Polymerase Activity of Yeast Rad30 Protein for Its Biological Function

1999 • 105 citations

Increased Activity and Fidelity of DNA Polymerase β on Single-nucleotide Gapped DNA

1997 • 104 citations

Different Mismatch Repair Deficiencies All Have the Same Effects on Somatic Hypermutation

1999 • 96 citations

Mice reconstituted with DNA polymerase β-deficient fetal liver cells are able to mount a T cell-dependent immune response and mutate their Ig genes normally

2000 • 94 citations

Uvm mutants of Escherichia coli K12 deficient in UV mutagenesis

1979 • 93 citations

Identification of a DinB/UmuC homolog in the archeon Sulfolobus solfataricus

1996 • 92 citations

Evolution of somatic hypermutation and gene conversion in adaptive immunity

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Somatic hypermutation and the three R's: repair, replication and recombination

1999 • 72 citations

Accuracy of thymine–thymine dimer bypass by Saccharomyces cerevisiae DNA polymerase η

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Mutagenesis by third-strand-directed psoralen adducts in repair-deficient human cells: high frequency and altered spectrum in a xeroderma pigmentosum variant.

1996 • 71 citations

Kinetic Analysis of Base Substitution Mutagenesis by Transient Misalignment of DNA and by Miscoding

1989 • 70 citations

Abnormal, Error-Prone Bypass of Photoproducts by Xeroderma Pigmentosum Variant Cell Extracts Results in Extreme Strand Bias for the Kinds of Mutations Induced by UV Light

1999 • 68 citations

Evidence from Mutation Spectra that the UV Hypermutability of Xeroderma Pigmentosum Variant Cells Reflects Abnormal, Error-Prone Replication on a Template Containing Photoproducts

1993 • 60 citations

Much of spontaneous mutagenesis in Escherichia coli is due to error-prone DNA repair: implications for spontaneous carcinogenesis

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Characteristics of Sequences Around Individual Nucleotide Substitutions in IgVH Genes Suggest Different GC and AT Mutators

1999 • 57 citations

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[21] Methods of analyzing processivity

1995 • 52 citations

SOS factors involved in translesion synthesis

1997 • 52 citations

Substitution of mucAB or rumAB for umuDC alters the relative frequencies of the two classes of mutations induced by a site-specific T-T cyclobutane dimer and the efficiency of translesion DNA synthesis

1996 • 52 citations

Detection of messenger RNA from the isoleucine-valine operons of Salmonella typhimurium by heterologous DNA-RNA hybridization: Involvement of transfer RNA in transcriptional repression

1977 • 49 citations

Xeroderma Pigmentosum Variants: Influence of Temperature on Dna Repair

1973 • 36 citations

Analysis of the mutagenic properties of the UmuDC, MucAB and RumAB proteins, using a site-specific abasic lesion

1996 • 21 citations

Somatic hypermutation and B-cell malignancies

1999 • 20 citations

Xeroderma pigmentosum variant associated with multiple cancers

1999 • 11 citations