The Saccharomyces cerevisiae RAD30 Gene, a Homologue of Escherichia coli dinB and umuC, Is DNA Damage Inducible and Functions in a Novel Error-Free Postreplication Repair Mechanism

Basic local alignment search tool

1990 • 87,358 citations

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1975 • 33,059 citations

Basic Local Alignment Search Tool

1990 • 12,947 citations

Transformation of intact yeast cells treated with alkali cations

1983 • 7,688 citations

DNA Repair and Mutagenesis

2006 • 4,725 citations

Improved method for high efficiency transformation of intact yeast cells

1992 • 3,258 citations

Elevated recombination rates in transcriptionally active DNA

1989 • 1,666 citations

[19] Targeting, disruption, replacement, and allele rescue: Integrative DNA transformation in yeast

1991 • 1,369 citations

A rapid and simple method for preparation of RNA fromSaccharomyces cerevisiae

1990 • 1,340 citations

Discontinuities in the DNA synthesized in an Excision-defective strain of Escherichia coli following ultraviolet irradiation

1968 • 1,089 citations

Issues in searching molecular sequence databases

1994 • 781 citations

FIDELITY MECHANISMS IN DNA REPLICATION

1991 • 709 citations

Thymine-Thymine Dimer Bypass by Yeast DNA Polymerase ζ

1996 • 655 citations

Exchanges between DNA strands in ultraviolet-irradiated Escherichia coli

1971 • 582 citations

[14] Genetic applications of yeast transformation with linear and gapped plasmids

1983 • 503 citations

A model for replication repair in mammalian cells

1976 • 443 citations

RecA-mediated cleavage activates UmuD for mutagenesis: mechanistic relationship between transcriptional derepression and posttranslational activation.

1988 • 415 citations

Deoxyribonucleic acid repair in the yeast Saccharomyces cerevisiae

1988 • 361 citations

UmuD mutagenesis protein of Escherichia coli: overproduction, purification, and cleavage by RecA.

1988 • 354 citations

RecA protein-dependent cleavage of UmuD protein and SOS mutagenesis.

1988 • 349 citations

Characterization of postreplication repair in Saccharomyces cerevisiae and effects of rad6, rad18, rev3 and rad52 mutations

1981 • 289 citations

Inducibility of a gene product required for UV and chemical mutagenesis in Escherichia coli.

1981 • 279 citations

REV3, a Saccharomyces cerevisiae gene whose function is required for induced mutagenesis, is predicted to encode a nonessential DNA polymerase

1989 • 270 citations

UmuC mutagenesis protein of Escherichia coli: purification and interaction with UmuD and UmuD'.

1989 • 222 citations

Saccharomyces cerevisiae RAD5-encoded DNA repair protein contains DNA helicase and zinc-binding sequence motifs and affects the stability of simple repetitive sequences in the genome.

1992 • 218 citations

Persistence of pyrimidine dimers during post-replication repair in ultraviolet light-irradiated Escherichia coli K12

1974 • 210 citations

Activity of the purified mutagenesis proteins UmuC, UmuD', and RecA in replicative bypass of an abasic DNA lesion by DNA polymerase III.

1992 • 199 citations

TheSaccharomyces cerevisiae RAD18gene encodes a protein that contains potential zinc finger domains for nucleic acid binding and a putative nucleotide binding sequence

1988 • 147 citations

The REV1 gene of Saccharomyces cerevisiae: isolation, sequence, and functional analysis

1989 • 145 citations

Deoxyribonucleic acid repair in the yeast Saccharomyces cerevisiae.

1988 • 139 citations

Role of RecA protein in untargeted UV mutagenesis of bacteriophage lambda: evidence for the requirement for the dinB gene.

1986 • 128 citations

Targeting of the UmuD, UmuD', and MucA' mutagenesis proteins to DNA by RecA protein.

1993 • 110 citations

Purification of a Soluble UmuD′C Complex from Escherichia coli

1996 • 105 citations

Requirement of proliferating cell nuclear antigen in RAD6-dependent postreplicational DNA repair.

1996 • 104 citations

Identification of a DinB/UmuC homolog in the archeon Sulfolobus solfataricus

1996 • 92 citations

3 Cellular Responses to DNA Damage in Yeast

1991 • 79 citations

A RecA protein mutant deficient in its interaction with the UmuDC complex

1991 • 73 citations

DNA synthesis in UV-irradiated yeast

1981 • 71 citations

dinP, a new gene in Escherichia coli, whose product shows similarities to UmuC and its homologues

1995 • 71 citations

Expression of theSaccharomyces cerevisiaeDNA repair geneRAD6that encodes a ubiquitin conjugating enzyme, increases in response to DNA damage and in meiosis but remains constant during the mitotic cell cycle

1990 • 63 citations

Cellular strategies for accommodating replication-hindering adducts in DNA: control by the SOS response in Escherichia coli.

1996 • 57 citations

A common element involved in transcriptional regulation of two DNA alkylation repair genes (MAG and MGT1) of Saccharomyces cerevisiae.

1993 • 54 citations

Damage inducible mutagenesis: recent insights into the activities of the Umu family of mutagenesis proteins.

1996 • 54 citations

Transcript levels of theSaccharomyces cerevisiaeDNA repair gene RAD18 increase in UV irradiated cells and during meiosis but not during the mitotic cell cycle

1991 • 51 citations

New mutations affecting induced mutagenesis in yeast

1985 • 39 citations

Fidelity Mechanisms In DNA Replication

1991 • 38 citations

Postreplication repair in Saccharomyces cerevisiae

1981 • 28 citations

Analysis of the mutagenic properties of the UmuDC, MucAB and RumAB proteins, using a site-specific abasic lesion

1996 • 21 citations

Synergistic interactions between RAD5, RAD16 and RAD54, three partially homologous yeast DNA repair genes each in a different repair pathway.

1994 • 16 citations

Saccharomyces cerevisiae RAD5-encoded DNA repair protein contains DNA helicase and zinc-binding sequence motifs and affects the stability of simple repetitive sequences in the genome.

1992 • 13 citations

Genetic control of the UV-induced SOS mutator effect in single- and double-stranded DNA phages

1990 • 12 citations