DNA polymerase insertion fidelity. Gel assay for site-specific kinetics.

Enzyme structure and mechanism

1978 • 2,897 citations

Fidelity of DNA Synthesis

1982 • 516 citations

Base-base mismatches. Thermodynamics of double helix formation for dCA₃XA₃G + dCT₃YT₃G (X, Y = A,C,G,D

1985 • 426 citations

Nucleotide sequence of the filamentous bacteriophage M13 DNA genome: comparison with phage fd

1980 • 405 citations

Identification of the epsilon-subunit of Escherichia coli DNA polymerase III holoenzyme as the dnaQ gene product: a fidelity subunit for DNA replication.

1983 • 212 citations

Nucleotide insertion kinetics opposite abasic lesions in DNA.

1987 • 209 citations

The mutational specificity of DNA polymerases-alpha and -gamma during in vitro DNA synthesis.

1985 • 176 citations

Studies on the biochemical basis of spontaneous mutation

1974 • 170 citations

Error induction and correction by mutant and wild type T4 DNA polymerases. Kinetic error discrimination mechanisms.

1979 • 167 citations

Comparison of nucleotide interactions in water, proteins, and vacuum: model for DNA polymerase fidelity.

1986 • 148 citations

Mutagenesis during in vitro DNA synthesis.

1978 • 147 citations

Isolation of an intact DNA polymerase-primase from embryos of Drosophila melanogaster.

1983 • 132 citations

Structural Studies of DNA Fragments: The G·T Wobble Base Pair in A, B and Z DNA; The G·A Base Pair in B-DNA

1985 • 130 citations

Accuracy in Molecular Processes

1986 • 123 citations

Influence of neighboring bases on DNA polymerase insertion and proofreading fidelity.

1985 • 98 citations

Enzymatic determinants of DNA polymerase accuracy. Theory of coliphage T4 polymerase mechanisms

1978 • 90 citations

The interaction of DNA polymerase III and the product of the Escherichia coli mutator gene, mutD.

1984 • 73 citations

Studies on the mechanism of DNA polymerase alpha. Nascent chain elongation, steady state kinetics, and the initiation phase of DNA synthesis.

1981 • 71 citations

Kinetic measurement of 2-aminopurine X cytosine and 2-aminopurine X thymine base pairs as a test of DNA polymerase fidelity mechanisms.

1982 • 53 citations

Influence of template primary and secondary structure on the rate and fidelity of DNA synthesis.

1985 • 48 citations

The DNA polymerase-primase from drosophila melanogaster embryos. Rate and fidelity of polymerization on single-stranded DNA templates.

1984 • 47 citations

Misincorporation during DNA synthesis, analyzed by gel electrophoresis

1984 • 40 citations

Influence of local nucleotide sequence on substitution of 2-aminopurine for adenine during deoxyribonucleic acid synthesis in vitro

1983 • 39 citations

A fidelity assay using "dideoxy" DNA sequencing: a measurement of sequence dependence and frequency of forming 5-bromouracil X guanine base mispairs.

1985 • 23 citations