Platelet-derived microparticles associate with fibrin during thrombosis

Leukocyte rolling and extravasation are severely compromised in P selectin-deficient mice

1993 • 1,058 citations

PADGEM protein: A receptor that mediates the interaction of activated platelets with neutrophils and monocytes

1989 • 878 citations

Histochemical demonstration of heavy metals

1981 • 758 citations

Detection of activated platelets in whole blood using activation- dependent monoclonal antibodies and flow cytometry

1987 • 736 citations

Complement proteins C5b-9 cause release of membrane vesicles from the platelet surface that are enriched in the membrane receptor for coagulation factor Va and express prothrombinase activity.

1988 • 663 citations

Assembly of the Platelet Prothrombinase Complex Is Linked to Vesiculation of the Platelet Plasma Membrane

1989 • 597 citations

Collagen fibril formation. Optimal in vitro conditions and preliminary kinetic results.

1978 • 468 citations

Platelet surface glycoproteins. Studies on resting and activated platelets and platelet membrane microparticles in normal subjects, and observations in patients during adult respiratory distress syndrome and cardiac surgery.

1986 • 457 citations

Direct detection of activated platelets and platelet-derived microparticles in humans

1990 • 429 citations

Annexin V as a probe of aminophospholipid exposure and platelet membrane vesiculation: a flow cytometry study showing a role for free sulfhydryl groups

1993 • 348 citations

Loss of membrane phospholipid asymmetry in platelets and red cells may be associated with calcium-induced shedding of plasma membrane and inhibition of aminophospholipid translocase

1990 • 290 citations

Comparison of anticoagulant and procoagulant activities of stimulated platelets and platelet-derived microparticles

1991 • 277 citations

Platelet-derived microparticles express high affinity receptors for factor VIII.

1991 • 277 citations

Interruption of acute platelet-dependent thrombosis by the synthetic antithrombin D-phenylalanyl-L-prolyl-L-arginyl chloromethyl ketone.

1988 • 274 citations

Selectins: Novel Receptors that Mediate Leukocyte Adhesion During Inflammation

1991 • 264 citations

Platelet adhesion to collagen types I through VIII under conditions of stasis and flow is mediated by GPIa/IIa (alpha 2 beta 1-integrin)

1994 • 256 citations

Clinical significance of platelet microparticles in autoimmune thrombocytopenias.

1992 • 254 citations

Elevated platelet microparticles in transient ischemic attacks, lacunar infarcts, and multiinfarct dementias

1993 • 251 citations

Platelet procoagulant activity: physiological significance and mechanisms of exposure

1991 • 177 citations

Ultrastructure of clots during isometric contraction.

1982 • 176 citations

Role of shear rate and platelets in promoting fibrin formation on rabbit subendothelium. Studies utilizing patients with quantitative and qualitative platelet defects.

1986 • 169 citations

P-selectin mediates Ca(2+)-dependent adhesion of activated platelets to many different types of leukocytes: detection by flow cytometry

1992 • 160 citations

Vesiculation of platelets during in vitro aging

1991 • 145 citations

Scott syndrome: a disorder of platelet coagulant activity.

1994 • 137 citations

[1] Isolation of human platelets from plasma by centrifugation and washing

1989 • 131 citations

Glycoprotein Ib, von Willebrand factor, and glycoprotein IIb:IIIa are all involved in platelet adhesion to fibrin in flowing whole blood

1990 • 124 citations

Expression of coagulant activity in human platelets: Release of membranous vesicles providing platelet factor 1 and platelet factor 3

1985 • 119 citations

Loss of membrane phospholipid asymmetry during activation of blood platelets and sickled red cells; mechanisms and physiological significance

1989 • 119 citations

Demonstration of Platelet-Derived Microvesicles in Blood from Patients with Activated Coagulation and Fibrinolysis Using a Filtration Technique and Western Blotting

1994 • 114 citations

Plasminogen activator inhibitor-1 released from activated platelets plays a key role in thrombolysis resistance. Studies with thrombi generated in the Chandler loop.

1994 • 101 citations

Leukocyte Interactions Mediated by P-Selection

1993 • 100 citations

Conformation-dependent platelet adhesion to collagen involving integrin alpha 2 beta 1-mediated and other mechanisms: multiple alpha 2 beta 1-recognition sites in collagen type I.

1994 • 100 citations

Generation and characterization of peptide-specific antibodies that inhibit von Willebrand factor binding to glycoprotein IIb-IIIa without interacting with other adhesive molecules. Selectivity is conferred by Pro1743 and other amino acid residues adjacent to the sequence Arg1744-Gly1745-Asp1746.

1988 • 90 citations

Reconstitution of collagen fibrils in vitro; the assembly process depends on the initiating procedure

1986 • 89 citations

Leukocyte Interactions Mediated by Selectins

1991 • 88 citations

Leiden fibrinolysis working party: blood collection and handling procedures for assessment of tissue-type plasminogen activator (t-PA) and plasminogen activator inhibitor-1 (PAI-1)

1990 • 81 citations

Immunochemical characterization of fibrinogen, fibrin I, and fibrin II in human thrombi and atherosclerotic lesions

1987 • 80 citations

Thrombin regulation of platelet interaction with damaged vessel wall and isolated collagen type I at arterial flow conditions in a porcine model: effects of hirudins, heparin, and calcium chelation

1991 • 77 citations

Binding of anticoagulant vitamin K-dependent protein S to platelet-derived microparticles

1992 • 75 citations

Detection of activated platelets in whole blood using activation- dependent monoclonal antibodies and flow cytometry

1987 • 67 citations

Glycoprotein IIb/IIIa Blockade Inhibits Platelet-mediated Force Development and Reduces Gel Elastic Modulus

1995 • 67 citations

[2] Isolation of human platelets by albumin gradient and gel filtration

1989 • 61 citations

Regulation of glycoprotein IIB/IIIA exposure on platelets stimulated with alpha-thrombin

1992 • 54 citations

Intact platelet membranes, not platelet-released microvesicles, support the procoagulant activity of adherent platelets.

1993 • 51 citations

In vivo studies of a synthetic inhibitor of thrombin.

1982 • 50 citations

Platelet membrane vesicles reduced microvascular bleeding times in thrombocytopenic rabbits.

1987 • 49 citations

Platelet microvesicles adhere to subendothelium and promote adhesion of platelets

1992 • 49 citations

Thrombin plays a key role in late platelet thrombus growth and/or stability. Effect of a specific thrombin inhibitor on thrombogenesis induced by aortic subendothelium exposed to flowing rabbit blood.

1994 • 48 citations

Effect of blood flow on thrombin generation is dependent on the nature of the thrombogenic surface

1994 • 44 citations

Inhibition of platelet adhesion to fibrin(ogen) in flowing whole blood by Arg-Gly-Asp and fibrinogen gamma-chain carboxy terminal peptides.

1992 • 40 citations

Effect of blood flow on thrombin generation is dependent on the nature of the thrombogenic surface

1994 • 40 citations

The Difference Between Platelet and Plasma FXIII Used to Study the Mechanism of Platelet Microvesicle Formation

1993 • 37 citations

Thrombin plays a key role in late platelet thrombus growth and/or stability. Effect of a specific thrombin inhibitor on thrombogenesis induced by aortic subendothelium exposed to flowing rabbit blood.

1994 • 36 citations

Comparison of the in vitro characteristics of von Willebrand factor in British and commercial factor VIII concentrates

1989 • 36 citations

Direct detection of activated platelets and platelet-derived microparticles in humans

1990 • 34 citations

Intact platelet membranes, not platelet-released microvesicles, support the procoagulant activity of adherent platelets.

1993 • 32 citations

Comparison of anticoagulant and procoagulant activities of stimulated platelets and platelet-derived microparticles

1991 • 29 citations

Immunolocalization of beta 1 integrins in platelets and platelet- derived microvesicles

1993 • 22 citations

Plasminogen activator production by human tumor cells: Effect on tumor cell‐extracellular matrix interactions

1987 • 15 citations

Glycoprotein Ib, von Willebrand factor, and glycoprotein IIb:IIIa are all involved in platelet adhesion to fibrin in flowing whole blood

1990 • 9 citations

The acceleratory effect of thrombin on fibrin clot assembly

1990 • 5 citations

Thrombin regulation of platelet interaction with damaged vessel wall and isolated collagen type I at arterial flow conditions in a porcine model: effects of hirudins, heparin, and calcium chelation

1991 • 5 citations

Location and Identification of Colloidal Gold Particles with an Energy-Dispersive Analyzer

1991 • 3 citations