Loss of membrane phospholipid asymmetry during activation of blood platelets and sickled red cells; mechanisms and physiological significance

Lipid Asymmetry in Membranes

1979 • 1,245 citations

Changes in membrane phospholipid distribution during platelet activation

1983 • 551 citations

Localization of red cell membrane constituents

1973 • 431 citations

In vivo recognition and clearance of red blood cells containing phosphatidylserine in their plasma membranes.

1985 • 352 citations

The role of activated human platelets in prothrombin and factor X activation

1985 • 240 citations

Transbilayer movement of fluorescent analogs of phosphatidylserine and phosphatidylethanolamine at the plasma membrane of cultured cells. Evidence for a protein-mediated and ATP-dependent process(es).

1987 • 238 citations

Interactions between membrane skeleton proteins and the intrinsic domain of the erythrocyte membrane

1982 • 235 citations

Membrane and lipid involvement in blood coagulation

1978 • 234 citations

Outside-inside translocation of aminophospholipids in the human erythrocyte membrane is mediated by a specific enzyme

1986 • 224 citations

Location of phosphatidylethanolamine and phosphatidylserine in the human platelet plasma membrane.

1976 • 198 citations

Uncoupling of the membrane skeleton from the lipid bilayer. The cause of accelerated phospholipid flip-flop leading to an enhanced procoagulant activity of sickled cells.

1985 • 182 citations

Platelet activation.

1985 • 172 citations

Red cell membrane skeletal defects in hereditary and acquired hemolytic anemias.

1983 • 169 citations

ATP‐dependent translocation of amino phospholipids across the human erythrocyte membrane

1986 • 157 citations

Release of spectrin-free spicules on reoxygenation of sickled erythrocytes

1982 • 153 citations

Impaired factor X and prothrombin activation associated with decreased phospholipid exposure in platelets from a patient with a bleeding disorder

1985 • 135 citations

Transbilayer movement of phosphatidylserine in erythrocytes: inhibition of transport and preferential labeling of a 31 000-dalton protein by sulfhydryl reactive reagents

1988 • 129 citations

Selective outside-inside translocation of aminophospholipids in human platelets

1987 • 117 citations

Phospholipid flippases

1988 • 87 citations

Prothrombin activation on phospholipid membranes with positive electrostatic potential

1988 • 77 citations

The involvement of cytoskeleton in the regulation of transbilayer movement of phospholipids in human blood platelets

1985 • 67 citations

An intracellular simian malarial parasite (Plasmodium knowlesi) induces stage-dependent alterations in membrane phospholipid organization of its host erythrocyte

1987 • 42 citations

Abnormal membrane phospholipid organization in Plasmodium falciparum-infected human erythrocytes

1988 • 38 citations

Involvement of platelet cytoskeleton and plasma membrane in the expression of procoagulant activity

1988 • 1 citations