Assembly of the Platelet Prothrombinase Complex Is Linked to Vesiculation of the Platelet Plasma Membrane

Lipid polymorphism and the functional roles of lipids in biological membranes

1979 • 1,817 citations

Changes in the platelet membrane glycoprotein IIb.IIIa complex during platelet activation.

1985 • 968 citations

Molecular mechanisms of platelet activation.

1989 • 903 citations

Exposure of platelet fibrinogen receptors by ADP and epinephrine.

1979 • 868 citations

Detection of activated platelets in whole blood using activation- dependent monoclonal antibodies and flow cytometry

1987 • 736 citations

Complement proteins C5b-9 cause release of membrane vesicles from the platelet surface that are enriched in the membrane receptor for coagulation factor Va and express prothrombinase activity.

1988 • 663 citations

Changes in membrane phospholipid distribution during platelet activation

1983 • 551 citations

Platelet surface glycoproteins. Studies on resting and activated platelets and platelet membrane microparticles in normal subjects, and observations in patients during adult respiratory distress syndrome and cardiac surgery.

1986 • 457 citations

A monoclonal antibody to a membrane glycoprotein binds only to activated platelets.

1984 • 456 citations

The Conversion of Prothrombin to Thrombin

1974 • 366 citations

Inhibition of fibrinogen binding to stimulated human platelets by a monoclonal antibody.

1983 • 280 citations

Identification of actin-binding protein as the protein linking the membrane skeleton to glycoproteins on platelet plasma membranes.

1985 • 236 citations

Membrane and lipid involvement in blood coagulation

1978 • 234 citations

Interactions of a fluorescent active-site-directed inhibitor of thrombin: dansylarginine N-(3-ethyl-1,5-pentanediyl)amide

1979 • 213 citations

Diagnosis of Bernard-Soulier syndrome and Glanzmann's thrombasthenia with a monoclonal assay on whole blood.

1983 • 185 citations

Complement proteins C5b-9 stimulate procoagulant activity through platelet prothrombinase

1986 • 183 citations

Role of shear rate and platelets in promoting fibrin formation on rabbit subendothelium. Studies utilizing patients with quantitative and qualitative platelet defects.

1986 • 169 citations

Isolated deficiency of platelet procoagulant activity

1979 • 165 citations

Impaired factor X and prothrombin activation associated with decreased phospholipid exposure in platelets from a patient with a bleeding disorder

1985 • 135 citations

Deficiency of factor Xa-factor Va binding sites on the platelets of a patient with a bleeding disorder

1979 • 120 citations

Expression of coagulant activity in human platelets: Release of membranous vesicles providing platelet factor 1 and platelet factor 3

1985 • 119 citations

Complement C5b-9-stimulated platelet secretion is associated with a Ca2+-initiated activation of cellular protein kinases.

1987 • 105 citations

Repolarization of the membrane potential of blood platelets after complement damage: evidence for a Ca++ -dependent exocytotic elimination of C5b-9 pores

1986 • 102 citations

On the mechanism by which complement proteins C5b-9 increase platelet prothrombinase activity.

1986 • 90 citations

Red-Cell and Platelet Fragmentation in Idiopathic Autoimmune Thrombocytopenic Purpura

1977 • 85 citations

Characteristics of the synergistic actions of platelet agonists

1981 • 83 citations

Epinephrine induces platelet fibrinogen receptor expression, fibrinogen binding, and aggregation in whole blood in the absence of other excitatory agonists

1989 • 74 citations

Association of factor V activity with membranous vesicles released from human platelets: Requirement for platelet stimulation

1985 • 69 citations

Characteristics of the synergistic actions of platelet agonists

1981 • 68 citations

The involvement of cytoskeleton in the regulation of transbilayer movement of phospholipids in human blood platelets

1985 • 67 citations

Regulation of Thrombin Generation at Cell Surfaces

1988 • 48 citations

Fluoride-dependent calcium-induced platelet procoagulant activity shows that calpain is involved in increased phospholipid transbilayer movement

1988 • 30 citations