Nitric oxide synthase inhibitors attenuate transforming-growth-factor-beta 1-stimulated capillary organization in vitro.

Nitric oxide: physiology, pathophysiology, and pharmacology.

1991 • 15,563 citations

Angiogenesis in cancer, vascular, rheumatoid and other disease

1995 • 7,717 citations

Angiogenic Factors

1987 • 3,702 citations

Cloned and expressed nitric oxide synthase structurally resembles cytochrome P-450 reductase

1991 • 2,371 citations

Hypertension in mice lacking the gene for endothelial nitric oxide synthase

1995 • 2,075 citations

Altered responses to bacterial infection and endotoxic shock in mice lacking inducible nitric oxide synthase

1995 • 1,454 citations

Targeted disruption of the neuronal nitric oxide synthase gene

1993 • 1,300 citations

Altered immune responses in mice lacking inducible nitric oxide synthase

1995 • 1,296 citations

The implications of angiogenesis for the biology and therapy of cancer metastasis

1994 • 1,120 citations

Nitric oxide synthase isozymes. Characterization, purification, molecular cloning, and functions.

1994 • 1,102 citations

Nitric oxide mediates angiogenesis in vivo and endothelial cell growth and migration in vitro promoted by substance P.

1994 • 858 citations

Roles of nitric oxide in tumor growth.

1995 • 791 citations

Two different laminin domains mediate the differentiation of human endothelial cells into capillary-like structures in vitro

1989 • 746 citations

Targeting of nitric oxide synthase to endothelial cell caveolae via palmitoylation: implications for nitric oxide signaling.

1996 • 677 citations

Evidence for a Regulated Interaction between Heterotrimeric G Proteins and Caveolin

1995 • 612 citations

Capillary endothelial cell cultures: phenotypic modulation by matrix components.

1983 • 611 citations

Mice lacking inducible nitric oxide synthase are not resistant to lipopolysaccharide-induced death.

1995 • 585 citations

Phenotypic modulation of endothelial cells by transforming growth factor-beta depends upon the composition and organization of the extracellular matrix.

1988 • 571 citations

Continuous nitric oxide synthesis by inducible nitric oxide synthase in normal human airway epithelium in vivo.

1995 • 517 citations

Nitric oxide triggers a switch to growth arrest during differentiation of neuronal cells

1995 • 484 citations

The Nitric Oxide Synthase Family of Proteins

1994 • 465 citations

Vascular endothelial growth factor induces EDRF-dependent relaxation in coronary arteries

1993 • 448 citations

Nitric oxide mediates mitogenic effect of VEGF on coronary venular endothelium

1996 • 423 citations

Nitric Oxide Activates Metalloprotease Enzymes in Articular Cartilage

1995 • 410 citations

Localization of Platelet-derived Growth Factor-stimulated Phosphorylation Cascade to Caveolae

1996 • 378 citations

Cloning of Inducible Nitric Oxide Synthase in Rat Vascular Smooth Muscle Cells

1993 • 319 citations

Endothelial cell proliferation during angiogenesis. In vitro modulation by basement membrane components.

1986 • 277 citations

Isothioureas: potent inhibitors of nitric oxide synthases with variable isoform selectivity

1995 • 274 citations

A Novel, Microcarrier-Based in Vitro Assay for Rapid and Reliable Quantification of Three-Dimensional Cell Migration and Angiogenesis

1995 • 244 citations

Palmitoylation of Endothelial Nitric Oxide Synthase Is Necessary for Optimal Stimulated Release of Nitric Oxide: Implications for Caveolae Localization

1996 • 243 citations

Collagen polymorphism in the lungAn immunochemical study of pulmonary fibrosis

1980 • 220 citations

Ca2+/calmodulin-dependent cytochrome c reductase activity of brain nitric oxide synthase.

1992 • 210 citations

Production of angiogenic activity by human monocytes requires an L-arginine/nitric oxide-synthase-dependent effector mechanism.

1994 • 205 citations

cGMP and Nitric Oxide Modulate Thrombin-Induced Endothelial Permeability

1995 • 201 citations

Molecular Regulation of the Bovine Endothelial Cell Nitric Oxide Synthase by Transforming Growth Factor–β ₁

1995 • 194 citations

Inhibition of nitric oxide synthase delays healing of chronic gastric ulcers

1993 • 188 citations

Transforming growth factor beta₁ modulates extracellular matrix organization and cell‐cell junctional complex formation during in vitro angiogenesis

1990 • 184 citations

Inhibitors of nitric oxide synthase selectively reduce flow in tumour‐associated neovasculature

1992 • 179 citations

Evidence that nitric oxide is an endogenous antiangiogenic mediator

1994 • 170 citations

Modulation of transforming growth factor beta receptor levels on microvascular endothelial cells during in vitro angiogenesis.

1996 • 161 citations

Inhibition of angiogenesis, tumour growth and metastasis by the NO‐releasing vasodilators, isosorbide mononitrate and dinitrate

1995 • 156 citations

Modulation of platelet-derived growth factor receptor expression in microvascular endothelial cells during in vitro angiogenesis.

1994 • 152 citations

Nitric Oxide Stimulates the Activity of a 72-kDa Neutral Matrix Metalloproteinase in Cultured Rat Mesangial Cells

1996 • 110 citations

Effects of soluble factors and extracellular matrix components on vascular cell behavior in vitro and in vivo: Models of de‐endothelialization and repair

1991 • 99 citations

Identification of covalently bound amino-terminal myristic acid in endothelial nitric oxide synthase.

1994 • 94 citations

Cloned and expressed nitric oxide synthase structurally resembles cytochrome P-450 reductase

1991 • 94 citations

Cytokine‐mediated induction of cyclo‐oxygenase‐2 by activation of tyrosine kinase in bovine endothelial cells stimulated by bacterial lipopolysaccharide

1995 • 92 citations

Expression and Expressional Control of Nitric Oxide Synthases in Various Cell Types

1995 • 90 citations

Expression of Two Types of Nitric Oxide Synthase mRNA in Human Neuroblastoma Cell Lines

1994 • 67 citations

cDNA cloning and expression of inducible nitric oxide synthase from rat vascular smooth muscle cells

1994 • 55 citations

Anoxic Injury of Endothelial Cells Increases Production of Nitric Oxide and Hydroxyl Radicals

1996 • 31 citations

Microvascular endothelial cells from E-selectin-deficient mice form tubes in vitro.

1996 • 28 citations