Sequential order of target-recognizing domains in multispecific DNA-methyltransferases.

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Molecular Cloning. A Laboratory Manual

1983 • 27,328 citations

A rapid alkaline extraction procedure for screening recombinant plasmid DNA

1979 • 15,511 citations

Improved M13 phage cloning vectors and host strains: nucleotide sequences of the M13mpl8 and pUC19 vectors

1985 • 15,222 citations

The pUC plasmids, an M13mp7-derived system for insertion mutagenesis and sequencing with synthetic universal primers

1982 • 6,153 citations

A complementation analysis of the restriction and modification of DNA in Escherichia coli

1969 • 3,866 citations

A new pair of M13 vectors for selecting either DNA strand of double-digest restriction fragments

1982 • 3,041 citations

A system for shotgun DNA sequencing

1981 • 2,710 citations

In vitro insertional mutagenesis with a selectable DNA fragment

1984 • 1,708 citations

PROTEIN-DNA RECOGNITION

1984 • 1,649 citations

Potential Metal-Binding Domains in Nucleic Acid Binding Proteins

1986 • 1,096 citations

[32] Oligonucleotide-directed mutagenesis of DNA fragments cloned into M13 vectors

1983 • 1,093 citations

High frequency transformation of Bacillus subtilis protoplasts by plasmid DNA

1979 • 977 citations

Construction and characterization of new cloning vehicles IV. Deletion derivatives of pBR322 and pBR325

1980 • 616 citations

The gapped duplex DNA approach to oligonucleotide-directed mutation construction

1984 • 511 citations

Stimulation by Cyclic Adenosine Monophosphate of Plasmid Deoxyribonucleic Acid Replication and Catabolite Repression of the Plasmid Deoxyribonucleic Acid-Protein Relaxation Complex

1973 • 505 citations

Structure of the DNA-Eco RI Endonuclease Recognition Complex at 3 Å Resolution

1986 • 492 citations

Kinetic and catalytic mechanism of HhaI methyltransferase.

1987 • 416 citations

Atomic Structure of Thymidylate Synthase: Target for Rational Drug Design

1987 • 329 citations

Active site and complete sequence of the suicidal methyltransferase that counters alkylation mutagenesis.

1985 • 221 citations

Precise location of two promoters for the beta-lactamase gene of pBR322. S1 mapping of ribonucleic acid isolated from Escherichia coli or synthesized in vitro.

1982 • 210 citations

Cloning restriction fragments that promote expression of a gene in Bacillus subtilis

1981 • 162 citations

Mutagenesis of plasmid DNA with hydroxylamine: Isolation of mutants of multi-copy plasmids

1976 • 151 citations

Nudeotide sequence of the BsuRI restriction-modification system

1985 • 135 citations

Molecular Cloning and Gene Regulation in Bacilli

1982 • 123 citations

Functional domains and methyl acceptor sites of the Escherichia coli ada protein.

1988 • 107 citations

Nucleotide sequence and expression of the gene encoding theEcoRII modification enzyme

1987 • 106 citations

Bacillus subtilis bacteriophage SPbeta: localization of the prophage attachment site, and specialized transduction

1977 • 100 citations

Construction and use of chimeric SPR/phi 3T DNA methyltransferases in the definition of sequence recognizing enzyme regions.

1987 • 96 citations

Cloning, sequencing, in vivo promoter mapping, and expression in Escherichia coli of the gene for the HhaI methyltransferase.

1987 • 90 citations

Cytosine-specific DNA modification interferes with plasmid establishment in Escherichia coli K12: Involvement of rglB

1986 • 82 citations

Organization of multispecific DNA methyltransferases encoded by temperate Bacillus subtilis phages.

1987 • 74 citations

The GATATC‐modification enzyme EcoRV is closely related to the GATC‐recognizing methyltransferases DpnII and dam from E. coli and phage T₄

1987 • 73 citations

DNA methyltransferase genes of Bacillus subtilis phages: comparison of their nucleotide sequences

1986 • 69 citations

Restriction and modification in Bacillus subtilis: nucleotide sequence, functional organization and product of the DNA methyltransferase gene of bacteriophage SPR

1984 • 67 citations

Structure of the Bacillus sphaericus R modification methylase gene

1983 • 65 citations

Restriction and modification in Bacillus subtilis: Identification of a gene in the temperate phage SPβ coding for a BsuR specific modification methyltransferase

1980 • 63 citations

Construction of mutants of Moloney murine leukemia virus by suppressor-linker insertional mutagenesis: positions of viable insertion mutations.

1984 • 61 citations

Restriction and modification in Bacillus subtilis: DNA methylation potential of the related bacteriophages Z, SPR, SP beta, phi 3T, and rho 11

1983 • 56 citations

Nuclotide sequence of theDdeI restriction-modification system and characterization of the methylase protein

1987 • 56 citations

Structure of the gene coding for the sequence-specific DNA-methyltransferase of theB. subtilisphage SPR

1984 • 53 citations

Functional role of cysteine-146 in Escherichia coli thymidylate synthase.

1988 • 43 citations

DNA methyltransferase genes of Bacillus subtilis phages: structural relatedness and gene expression

1985 • 36 citations

Cloning and expression of Bacillus subtilis phage DNA methyltransferase genes in Escherichia coli and B. subtilis

1986 • 28 citations

Multispecific DNA methyltransferases from Bacillus subtilis phages

1986 • 25 citations

Restriction and Modification in Bacillus subtilis : Gene Coding for a Bsu R-Specific Modification Methyltransferase in the Temperate Bacteriophage Φ3T

1981 • 25 citations

Mutational analysis of the cloned chicken thymidine kinase gene.

1983 • 15 citations

Highly efficient positive selection of recombinant plasmids using a novel rglB-based Escherichia coli K-12 vector system

1988 • 9 citations

A new mutator strain of Bacillus subtilis

1987 • 6 citations