Functional domains and methyl acceptor sites of the Escherichia coli ada protein.

Close similarity of epidermal growth factor receptor and v-erb-B oncogene protein sequences

1984 • 2,564 citations

A new pathway for DNA repair in Escherichia coli

1977 • 705 citations

Staphylococcal Protease: A Proteolytic Enzyme Specific for Glutamoyl Bonds

1972 • 703 citations

REGULATION AND EXPRESSION OF THE ADAPTIVE RESPONSE TO ALKYLATING AGENTS

1988 • 645 citations

Repair of alkylated DNA in Escherichia coli. Methyl group transfer from O6-methylguanine to a protein cysteine residue.

1980 • 438 citations

Adaptive response to alkylating agents involves alteration in situ of O6-methylguanine residues in DNA

1979 • 260 citations

The lambda repressor contains two domains.

1979 • 238 citations

The intracellular signal for induction of resistance to alkylating agents in E. coli

1986 • 222 citations

Active site and complete sequence of the suicidal methyltransferase that counters alkylation mutagenesis.

1985 • 221 citations

The basis for colored silver-protein complex formation in stained polyacrylamide gels

1984 • 199 citations

Repair of alkylated DNA in Escherichia coli. Physical properties of O6-methylguanine-DNA methyltransferase.

1982 • 172 citations

Induction of resistance to alkylating agents in E. coli: the ada+ gene product serves both as a regulatory protein and as an enzyme for repair of mutagenic damage.

1984 • 162 citations

Mechanisms and consequences of DNA damage processing

1987 • 152 citations

Methyl phosphotriesters in alkylated DNA are repaired by the Ada regulatory protein ofE. coli

1985 • 139 citations

O6-Methylguanine-DNA methyltransferase of human lymphoid cells: structural and kinetic properties and absence in repair-deficient cells.

1983 • 125 citations

Purification and structure of the intact Ada regulatory protein of Escherichia coli K12, O6-methylguanine-DNA methyltransferase.

1985 • 124 citations

Molecular cloning of a gene which regulates the adaptive response to alkylating agents in Escherichia coli

1983 • 110 citations

Regulatory mechanisms for induction of synthesis of repair enzymes in response to alkylating agents: ada protein acts as a transcriptional regulator.

1986 • 108 citations

Induction and autoregulation of ada, a positively acting element regulating the response of Escherichia coli K-12 to methylating agents

1985 • 87 citations

Complementation of sensitivity to alkylating agents in Escherichia coli and Chinese hamster ovary cells by expression of a cloned bacterial DNA repair gene.

1986 • 82 citations

Deletion mutagenesis using an ‘M13 splint’: the N-terminal structural domain of tyrosyl-tRNA synthetase (B. stearothermophilus) catalyses the formation of tyrosyl adenylate.

1983 • 82 citations

Sequences of theE. coli uvrBgene and protein

1986 • 63 citations

Functions of isolated domains of methionyl-tRNA synthetase from an extreme thermophile, Thermus thermophilus HB8.

1987 • 36 citations

Repair of DNA lesions introduced by N-nitroso compounds

1986 • 30 citations

MutantEscherichia coliAda proteins simultaneously defective in the repair of O⁶-metbylguanine and in gene activation

1986 • 28 citations

Sensitization of the Escherichia coli cyclic AMP receptor protein to trypsin cleavage by polydeoxyribonucleotides and polyribonucleotides.

1986 • 12 citations

Deleted Work

1955 • 0 citations