Regulation and a possible stage-specific function of Oct-2 during pre-B-cell differentiation.

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

Molecular cloning: A laboratory manual

1990 • 85,659 citations

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications.

1979 • 54,907 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

Rapid detection of octamer binding proteins with ‘mini extracts’, prepared from a small number of cells

1989 • 4,279 citations

Basic Methods in Molecular Biology

1986 • 3,284 citations

Multiple nuclear factors interact with the immunoglobulin enhancer sequences

1986 • 2,771 citations

Current Protocols in Molecular Biology

2001 • 2,451 citations

IκB: a Specific Inhibitor of the NF-κB Transcription Factor

1988 • 2,203 citations

Inducibility of κ immunoglobulin enhancer-binding protein NF-κB by a posttranslational mechanism

1986 • 2,043 citations

A nuclear factor for IL-6 expression (NF-IL6) is a member of a C/EBP family.

1990 • 1,517 citations

A lymphocyte-specific cellular enhancer is located downstream of the joining region in immunoglobulin heavy chain genes

1983 • 1,449 citations

A tissue-specific transcription enhancer element is located in the major intron of a rearranged immunoglobulin heavy chain gene

1983 • 1,418 citations

A nuclear factor that binds to a conserved sequence motif in transcriptional control elements of immunoglobulin genes

1986 • 1,150 citations

A tissue-specific transcription factor containing a homeodomain specifies a pituitary phenotype

1988 • 998 citations

A POU-domain transcription factor in early stem cells and germ cells of the mammalian embryo

1990 • 924 citations

Expression of a large family of POU-domain regulatory genes in mammalian brain development

1989 • 828 citations

The pituitary-specific transcription factor GHF-1 is a homeobox-containing protein

1988 • 771 citations

New type of POU domain in germ line-specific protein Oct-4

1990 • 753 citations

The POU domain: a large conserved region in the mammalian pit-1, oct-1, oct-2, and Caenorhabditis elegans unc-86 gene products.

1988 • 750 citations

A novel octamer binding transcription factor is differentially expressed in mouse embryonic cells

1990 • 745 citations

A lymphoid-specific protein binding to the octamer motif of immunoglobulin genes

1986 • 740 citations

Ordered rearrangement of immunoglobulin heavy chain variable region segments.

1984 • 736 citations

Developmentally controlled and tissue-specific expression of unrearranged VH gene segments

1985 • 710 citations

Differential transcriptional activation by Oct-1 and Oct-2: Interdependent activation domains induce Oct-2 phosphorylation

1990 • 696 citations

The ubiquitous octamer-binding protein Oct-1 contains a POU domain with a homeo box subdomain.

1988 • 670 citations

Correct transcription of an immunoglobulin κ gene requires an upstream fragment containing conserved sequence elements

1984 • 669 citations

Protein-Binding Sites in Ig Gene Enhancers Determine Transcriptional Activity and Inducibility

1987 • 619 citations

Cell-type specificity of iminunoglobulin gene expression is regulated by at least three DNA sequence elements

1985 • 588 citations

Structure of the 5' ends of immunoglobulin genes: a novel conserved sequence.

1984 • 564 citations

A cloned octamer transcription factor stimulates transcription from lymphoid–specific promoters in non–B cells

1988 • 494 citations

Expression and regulation of immunoglobulin heavy chain gene transfected into lymphoid cells.

1983 • 457 citations

The B-cell-specific Oct-2 protein contains POU box- and homeo box-type domains.

1988 • 429 citations

Regulation of the Assembly and Expression of Variable-Region Genes

1986 • 402 citations

Immunoglobulin gene expression in transformed lymphoid cells.

1983 • 400 citations

A human lymphoid- specific transcription factor that activates immunoglobulin genes is a homoeobox protein

1988 • 399 citations

An octamer oligonucleotide upstream of a TATA motif is sufficient for lymphoid-specific promoter activity

1987 • 398 citations

Murine B Cell Leukemia Line with Inducible Surface Immunoglobulin Expression

1978 • 388 citations

The C. elegans cell lineage and differentiation gene unc-86 encodes a protein with a homeodomain and extended similarity to transcription factors

1988 • 334 citations

Transcription cell type specificity is conferred by an immunoglobulin VH gene promoter that includes a functional consensus sequence

1985 • 313 citations

Cloning of a Lymphoid-Specific cDNA Encoding a Protein Binding the Regulatory Octamer DNA Motif

1988 • 304 citations

Identification of a novel lymphoid specific octamer binding protein (OTF-2B) by proteolytic clipping bandshift assay (PCBA).

1988 • 284 citations

Continuing kappa-gene rearrangement in a cell line transformed by Abelson murine leukemia virus

1982 • 278 citations

The role of the κ enhancer and its binding factor NF-κB in the developmental regulation of κ gene transcription

1987 • 247 citations

The octamer-binding proteins form multi-protein--DNA complexes with the HSV alpha TIF regulatory protein.

1989 • 245 citations

Oct-6: a POU transcription factor expressed in embryonal stem cells and in the developing brain.

1990 • 238 citations

A human protein specific for the immunoglobulin octamer DNA motif contains a functional homeobox domain

1988 • 234 citations

Cμ-containing transcripts initiate heterogeneously within the IgH enhancer region and contain a novel 5′-nontranslatable exon

1985 • 232 citations

The Basics of Molecular Biology

1986 • 231 citations

A second B cell-specific enhancer 3' of the immunoglobulin heavy-chain locus

1990 • 220 citations

Regulation of the pituitary-specific homeobox gene GHF1 by cell-autonomous and environmental cues

1990 • 215 citations

The immunoglobulin kappa locus contains a second, stronger B-cell-specific enhancer which is located downstream of the constant region.

1989 • 213 citations

Ribonuclease Protection Assay

1993 • 207 citations

Bacterial lipopolysaccharide (endotoxin) enhances expression and secretion of beta 2 interferon by human fibroblasts.

1987 • 199 citations

Interleukin 1 and cyclic AMP induce kappa immunoglobulin light-chain expression via activation of an NF-kappa B-like DNA-binding protein.

1989 • 176 citations

Immunoglobulin Gene Rearrangement in Immature B Cells

1980 • 172 citations

Mouse Bone Marrow Lymphocytes and Their Differentiation

1974 • 154 citations

Transcription factor Oct-2A contains functionally redundant activating domains and works selectively from a promoter but not from a remote enhancer position in non-lymphoid (HeLa) cells.

1990 • 146 citations

Beta transforming growth factors are potential regulators of B lymphopoiesis.

1987 • 145 citations

The cell type-specific octamer transcription factor OTF-2 has two domains required for the activation of transcription.

1990 • 139 citations

Octamer transcription factors bind to two different sequence motifs of the immunoglobulin heavy chain promoter.

1989 • 139 citations

Feedback inhibition of immunoglobulin gene rearrangement by membrane mu, but not by secreted mu heavy chains.

1988 • 138 citations

Interleukin 1-mediated induction of kappa-light chain synthesis and surface immunoglobulin expression on pre-B cells.

1984 • 134 citations

The Oct-2 protein binds cooperatively to adjacent octamer sites.

1989 • 132 citations

Functional cooperativity between protein molecules bound at two distinct sequence elements of the immunoglobulin heavy-chain promoter

1989 • 128 citations

Structure and expression of the mouse Oct2a and Oct2b, two differentially spliced products of the same gene

1990 • 125 citations

Multiple DNA sequence elements are necessary for the function of an immunoglobulin heavy chain promoter.

1987 • 123 citations

A labile inhibitor blocks immunoglobulin kappa-light-chain-gene transcription in a pre-B leukemic cell line.

1986 • 109 citations

A novel enhancer in the immunoglobulin lambda locus is duplicated and functionally independent of NF kappa B.

1990 • 104 citations

The coupling between enhancer activity and hypomethylation of kappa immunoglobulin genes is developmentally regulated.

1988 • 96 citations

Autoregulation - a common property of eukaryotic transcription factors?

1989 • 88 citations

Inducible transcription of the unrearranged kappa constant region locus is a common feature of pre-B cells and does not require DNA or protein synthesis.

1985 • 79 citations

Induction of κ Transcription by Interferon-γ Without Activation of NF-κB

1988 • 75 citations

Growth regulation of the B lymphoma cell line WEHI-231 by anti-immunoglobulin, lipopolysaccharide, and other bacterial products.

1986 • 74 citations

Lipopolysaccharide-induced transcription of the kappa immunoglobulin locus occurs on both alleles and is independent of methylatlon status

1984 • 65 citations

Extinction of an immunoglobulin κ promoter in cell hybrids is mediated by the octamer motif and correlates with suppression of Oct-2 expression

1990 • 61 citations

Initiation and processing of two kappa immunoglobulin germ line transcripts in mouse B cells.

1990 • 59 citations

The temporal order of appearance of transcripts from unrearranged and rearranged Ig genes in murine fetal liver.

1990 • 58 citations

Interleukin 1 and Cyclic AMP Induce κ Immunoglobulin Light-Chain Expression via Activation of an NF-κB-Like DNA-Binding Protein

1989 • 57 citations

B lymphocyte differentiation induced by lipopolysaccharide. II. Response of fetal lymphocytes.

1975 • 56 citations

Extinction of Ig genes expression in myeloma x fibroblast somatic cell hybrids is accompanied by repression of the oct-2 gene encoding a B-cell specific transcription factor.

1990 • 49 citations

Homoeo boxes, POU proteins and the limits to promiscuity

1988 • 45 citations

Synthesis of messenger RNA-like molecules in isolated myeloma nuclei

1977 • 43 citations

The Coupling Between Enhancer Activity and Hypomethylation of κ Immunoglobulin Genes is Developmentally Regulated

1988 • 36 citations

Identification of a second inducible DNA-protein interaction in the kappa immunoglobulin enhancer

1990 • 35 citations

Identification of an octamer-binding site in the mouse kappa light-chain immunoglobulin enhancer.

1989 • 35 citations

Immunoglobulin gene transcription: molecular mechanisms

1989 • 33 citations

Regulation of the Assembly and Expression of Variable-Region Genes

1986 • 32 citations

Identification of an octamer-binding site in the human kappa light-chain enhancer.

1990 • 16 citations

Identification of an Octamer-Binding Site in the Mouse Kappa Light-Chain Immunoglobulin Enhancer

1989 • 15 citations

Identification of an Octamer-Binding Site in the Human Kappa Light-Chain Enhancer

1990 • 9 citations

Deleted Work

1955 • 0 citations