Kinetics of Transcription Factors Regulating the RANTES Chemokine Gene Reveal a Developmental Switch in Nuclear Events During T-Lymphocyte Maturation

PCR protocols — A guide to methods and applications

1990 • 12,897 citations

Function and Activation of NF-kappaB in the Immune System

1994 • 4,698 citations

pEF-BOS, a powerful mammalian expression vector

1990 • 1,641 citations

Selective attraction of monocytes and T lymphocytes of the memory phenotype by cytokine RANTES

1990 • 1,378 citations

Contingent Genetic Regulatory Events in T Lymphocyte Activation

1989 • 1,108 citations

Transcription factors NF-IL6 and NF-kappa B synergistically activate transcription of the inflammatory cytokines, interleukin 6 and interleukin 8.

1993 • 955 citations

Compilation of vertebrate-encoded transcription factors

1992 • 934 citations

Biology and biochemistry of the chemokines: a family of chemotactic and inflammatory cytokines.

1992 • 737 citations

Preferential Migration of Activated CD4 ⁺ and CD8 ⁺ T Cells in Response to MIP-1α and MIP-1β

1993 • 737 citations

Biology of the rantes/sis cytokine family

1991 • 688 citations

Cytokine RANTES released by thrombin-stimulated platelets is a potent attractant for human eosinophils.

1992 • 683 citations

Cyclosporin A Specifically Inhibits Function of Nuclear Proteins Involved in T Cell Activation

1989 • 679 citations

LEF-1, a gene encoding a lymphoid-specific protein with an HMG domain, regulates T-cell receptor alpha enhancer function [corrected]

1991 • 627 citations

NF-AT components define a family of transcription factors targeted in T-cell activation

1994 • 573 citations

Commentary: “The Role of T3 Surface Molecules in the Activation of Human Cells: A Two-Stimulus Requirement for IL-2 Production Reflects Events Occurring at a Pretranslational Level”

2015 • 572 citations

IL‐6 and NF‐IL6 in Acute‐Phase Response and Viral Infection

1992 • 540 citations

NF-ATp: a transcription factor required for the co-ordinate induction of several cytokine genes

1994 • 523 citations

Transmission of Signals from the T Lymphocyte Antigen Receptor to the Genes Responsible for Cell Proliferation and Immune Function: The Missing Link

1990 • 517 citations

A human T cell-specific molecule is a member of a new gene family.

1988 • 500 citations

Selective Events in T Cell Development

1994 • 486 citations

The role of T3 surface molecules in the activation of human T cells: a two-stimulus requirement for IL 2 production reflects events occurring at a pre-translational level.

1984 • 455 citations

Characterization of antigen receptor response elements within the interleukin-2 enhancer.

1988 • 451 citations

Human cutaneous T cell lymphoma and leukemia cell lines produce and respond to T cell growth factor

1981 • 340 citations

Expression of the cytokine RANTES in human rheumatoid synovial fibroblasts. Differential regulation of RANTES and interleukin-8 genes by inflammatory cytokines.

1993 • 296 citations

Genomic organization and transcriptional regulation of the RANTES chemokine gene.

1993 • 273 citations

RANTES chemokine expression in cell-mediated transplant rejection of the kidney

1994 • 267 citations

Regulation of cytomegalovirus gene expression: alpha and beta promoters are trans activated by viral functions in permissive human fibroblasts

1985 • 229 citations

NFATx, a Novel Member of the Nuclear Factor of Activated T Cells Family That Is Expressed Predominantly in the Thymus

1995 • 211 citations

The inhibitory ankyrin and activator Rel proteins

1992 • 185 citations

LEF-1 contains an activation domain that stimulates transcription only in a specific context of factor-binding sites.

1993 • 161 citations

Involvement of CD28 in MHC-unrestricted cytotoxicity mediated by a human natural killer leukemia cell line.

1992 • 159 citations

Transcriptional Regulation of T Cell Receptor Genes

1993 • 142 citations

The granulocyte-macrophage colony-stimulating factor promoter cis-acting element CLE0 mediates induction signals in T cells and is recognized by factors related to AP1 and NFAT.

1993 • 131 citations

NF-AT-AP-1 and Rel-bZIP: Hybrid vigor and binding under the influence

1994 • 118 citations

T-Cell Effector Functions: Mechanisms for Delivery of Cytotoxicity and Help

1991 • 103 citations

Cytotoxic T lymphocytes specific for self tumor immunoglobulin express T cell receptor delta chain.

1989 • 95 citations

TNFα induces expression of the chemoattractant cytokine RANTES in cultured mouse mesangial cells

1993 • 91 citations

Identification of a novel regulatory region critical for expression of the RANTES chemokine in activated T lymphocytes.

1996 • 85 citations

Nuclear factor NF-kappa B can interact functionally with its cognate binding site to provide lymphoid-specific promoter function.

1988 • 77 citations

An intricate arrangement of binding sites for the Ets family of transcription factors regulates activity of the alpha 4 integrin gene promoter.

1994 • 76 citations

Structure of the human perforin gene. A simple gene organization with interesting potential regulatory sequences.

1989 • 75 citations

Cloning, genomic organization, and chromosomal localization of the Scya5 gene encoding the murine chemokine RANTES.

1994 • 67 citations

Definition of a lipopolysaccharide-responsive element in the 5'-flanking regions of MuRantes and crg-2.

1994 • 51 citations

Monocyte haptotaxis induced by the RANTES chemokine

1993 • 49 citations

The 5'-flanking region of the human CGL-1/granzyme B gene targets expression of a reporter gene to activated T-lymphocytes in transgenic mice.

1991 • 43 citations

Consensus AP-1 and CRE motifs upstream from the human cytotoxic serine protease B (CSP-B/CGL-1) gene synergize to activate transcription

1993 • 41 citations

Identification of a Killer Cell-Specific Regulatory Element of the Mouse Perforin Gene: an Ets-Binding Site-Homologous Motif That Interacts with Ets-Related Proteins

1993 • 37 citations

Recognition of an HLA public determinant (Bw4) by human allogeneic cytotoxic T lymphocytes.

1990 • 24 citations

Transgenic control of perforin gene expression. Functional evidence for two separate control regions.

1995 • 23 citations

Biology of the chemokine RANTES

1995 • 10 citations