High Endothelial Venules: Lymphocyte Traffic Control and Controlled Traffic**This article was accepted for publication on 27 September 1996.

Traffic signals for lymphocyte recirculation and leukocyte emigration: The multistep paradigm

1994 • 7,068 citations

Adhesion receptors of the immune system

1990 • 6,585 citations

Biological roles of oligosaccharides: all of the theories are correct

1993 • 5,121 citations

Integrins: A family of cell surface receptors

1987 • 4,322 citations

Lymphocyte Homing and Homeostasis

1996 • 2,934 citations

Leukocyte-endothelial cell recognition: Three (or more) steps to specificity and diversity

1991 • 2,806 citations

CD44 is the principal cell surface receptor for hyaluronate

1990 • 2,433 citations

VCAM-1 on activated endothelium interacts with the leukocyte integrin VLA-4 at a site distinct from the VLA-4/Fibronectin binding site

1990 • 1,836 citations

Traffic Signals on Endothelium for Lymphocyte Recirculation and Leukocyte Emigration

1995 • 1,525 citations

A cell-surface molecule involved in organ-specific homing of lymphocytes

1983 • 1,515 citations

The route of re-circulation of lymphocytes in the rat

1964 • 1,449 citations

α4β7 integrin mediates lymphocyte binding to the mucosal vascular addressin MAdCAM-1

1993 • 1,427 citations

Selective attraction of monocytes and T lymphocytes of the memory phenotype by cytokine RANTES

1990 • 1,378 citations

Selectins: Interpreters of Cell-Specific Carbohydrate Information During Inflammation

1992 • 1,255 citations

The Molecular Biology of Leukocyte Chemoattractant Receptors

1994 • 1,224 citations

Neutrophil Mac-1 and MEL-14 Adhesion Proteins Inversely Regulated by Chemotactic Factors

1989 • 1,135 citations

PECAM-1 is required for transendothelial migration of leukocytes.

1993 • 1,134 citations

Adhesion between epithelial cells and T lymphocytes mediated by E-cadherin and the αEβ7 integrin

1994 • 1,131 citations

CD44 and Its Interaction with Extracellular Matrix

1993 • 1,082 citations

The Neutrophil-Activating Protein (NAP-1) Is Also Chemotactic for T Lymphocytes

1989 • 1,060 citations

PECAM-1 (CD31) Cloning and Relation to Adhesion Molecules of the Immunoglobulin Gene Superfamily

1990 • 948 citations

Selectin ligands.

1994 • 943 citations

T-cell adhesion induced by proteoglycan-immobilized cytokine MIP-lβ

1993 • 896 citations

Endothelial cell interactions with granulocytes: tethering and signaling molecules

1992 • 773 citations

Recombinant human interferon-inducible protein 10 is a chemoattractant for human monocytes and T lymphocytes and promotes T cell adhesion to endothelial cells.

1993 • 755 citations

Biology of Animal Lectins

1993 • 752 citations

Preferential Migration of Activated CD4 ⁺ and CD8 ⁺ T Cells in Response to MIP-1α and MIP-1β

1993 • 737 citations

Expression cloning of a functional glycoprotein ligand for P-selectin

1993 • 734 citations

A tissue-specific endothelial cell molecule involved in lymphocyte homing

1988 • 725 citations

The α(1,3)Fucosyltransferase Fuc-TVII Controls Leukocyte Trafficking through an Essential Role in L-, E-, and P-selectin Ligand Biosynthesis

1996 • 723 citations

Molecular and cellular properties of PECAM-1 (endoCAM/CD31): a novel vascular cell-cell adhesion molecule.

1991 • 719 citations

Lymphocyte interactions with endothelial cells

1992 • 689 citations

Lymphocyte homing into lymph nodes: in vitro demonstration of the selective affinity of recirculating lymphocytes for high-endothelial venules.

1976 • 680 citations

An endothelial ligand for L-Selectin is a novel mucin-like molecule

1992 • 660 citations

Hyaluronate can function as a cell adhesion molecule and CD44 participates in hyaluronate recognition.

1990 • 639 citations

Immunohistologic and functional characterization of a vascular addressin involved in lymphocyte homing into peripheral lymph nodes.

1988 • 639 citations

Binding of L-Selectin to the Vascular Sialomucin CD34

1993 • 629 citations

Role of alpha 4-integrins in lymphocyte homing to mucosal tissues in vivo.

1994 • 625 citations

Lymphocyte recognition of high endothelium: antibodies to distinct epitopes of an 85-95-kD glycoprotein antigen differentially inhibit lymphocyte binding to lymph node, mucosal, or synovial endothelial cells.

1987 • 554 citations

Evidence that cutaneous antigen-presenting cells migrate to regional lymph nodes during contact sensitization.

1990 • 543 citations

Vascular cell adhesion molecule-1 mediates lymphocyte adherence to cytokine-activated cultured human endothelial cells [published erratum appears in Blood 1990 Dec 1;76(11):2420]

1990 • 540 citations

L-selectin-mediated lymphocyte rolling on MAdCAM-1

1993 • 540 citations

Cloning of a lymphocyte homing receptor reveals a lectin domain

1989 • 522 citations

Distinct roles of L-selectin and integrins α4β7 and LFA-1 in lymphocyte homing to Peyer's patch-HEV in situ: The multistep model confirmed and refined

1995 • 520 citations

Identification of a specific glycoprotein ligand for P-selectin (CD62) on myeloid cells.

1992 • 519 citations

Distinction of virgin and memory T lymphocytes. Stable acquisition of the Pgp-1 glycoprotein concomitant with antigenic stimulation.

1987 • 505 citations

The recirculation of lymphocytes from blood to lymph in the rat

1959 • 500 citations

Identification of a murine Peyer's patch—specific lymphocyte homing receptor as an integrin molecule with an α chain homologous to human VLA-4α

1989 • 495 citations

Role of Rho in Chemoattractant-Activated Leukocyte Adhesion Through Integrins

1996 • 494 citations

Endothelial cell binding of NAP-1/IL-8: role in neutrophil emigration

1992 • 477 citations

Involvement of Platelet-Endothelial Cell Adhesion Molecule-1 in Neutrophil Recruitment in Vivo

1993 • 468 citations

Photolabeling of Prostaglandin Endoperoxide H Synthase-1 with 3-Trifluoro-3-(m-[125I]iodophenyl)diazirine as a Probe of Membrane Association and the Cyclooxygenase Active Site

1996 • 460 citations

A lymphoid cell surface glycoprotein involved in endothelial cell recognition and lymphocyte homing in man

1986 • 435 citations

Mouse Lymph Node Homing Receptor cDNA Clone Encodes a Glycoprotein Revealing Tandem Interaction Domains

1989 • 428 citations

Soluble L-selectin is present in human plasma at high levels and retains functional activity.

1992 • 422 citations

CD44 and its ligand hyaluronate mediate rolling under physiologic flow: a novel lymphocyte-endothelial cell primary adhesion pathway.

1996 • 421 citations

Leukocyte-endothelial cell recognition: evidence of a common molecular mechanism shared by neutrophils, lymphocytes, and other leukocytes.

1987 • 417 citations

Inducible cell adhesion molecule 110 (INCAM-110) is an endothelial receptor for lymphocytes. A CD11/CD18-independent adhesion mechanism.

1990 • 408 citations

Control of lymphocyte recirculation in man. II. Differential regulation of the cutaneous lymphocyte-associated antigen, a tissue-selective homing receptor for skin-homing T cells.

1993 • 393 citations

MAdCAM-1 has homology to immunoglobulin and mucin-like adhesion receptors and to IgA1

1993 • 383 citations

CD31 expressed on distinctive T cell subsets is a preferential amplifier of beta 1 integrin-mediated adhesion.

1992 • 383 citations

A central role for microvillous receptor presentation in leukocyte adhesion under flow

1995 • 380 citations

Leukocyte Migration and Adhesion

1995 • 365 citations

The E-selectin-ligand ESL-1 is a variant of a receptor for fibroblast growth factor

1995 • 358 citations

Control of lymphocyte recirculation in man. I. Differential regulation of the peripheral lymph node homing receptor L-selectin on T cells during the virgin to memory cell transition.

1993 • 349 citations

Regulation of murine lymphokine production in vivo. III. The lymphoid tissue microenvironment exerts regulatory influences over T helper cell function.

1990 • 349 citations

Organ specificity of lymphocyte migration: mediation by highly selective lymphocyte interaction with organ‐specific determinants on high endothelial venules

1980 • 347 citations

Role of integrin alpha 4 beta 7/alpha 4 beta P in lymphocyte adherence to fibronectin and VCAM-1 and in homotypic cell clustering

1992 • 334 citations

Sulphation requirement for GlyCAM-1, an endothelial ligand for L-selectin

1993 • 330 citations

Granulocyte-macrophage colony-stimulating factor and other cytokines regulate surface expression of the leukocyte adhesion molecule-1 on human neutrophils, monocytes, and their precursors.

1990 • 325 citations

A 90-Kilodalton Endothelial Cell Molecule Mediating Lymphocyte Binding in Humans

1992 • 313 citations

Isolation and chromosomal localization of cDNAs encoding a novel human lymphocyte cell surface molecule, LAM-1. Homology with the mouse lymphocyte homing receptor and other human adhesion proteins.

1989 • 308 citations

Identification of a carbohydrate-based endothelial ligand for a lymphocyte homing receptor.

1991 • 308 citations

The human peripheral lymph node vascular addressin is a ligand for LECAM-1, the peripheral lymph node homing receptor.

1991 • 307 citations

Platelet-Mediated Lymphocyte Delivery to High Endothelial Venules

1996 • 305 citations

Evidence for an accessory role of LFA-1 in lymphocyte-high endothelium interaction during homing.

1988 • 302 citations

Monoclonal antibody to murine PECAM-1 (CD31) blocks acute inflammation in vivo.

1994 • 296 citations

Leukocyte interactions with vascular endothelium. New insights into selectin-mediated attachment and rolling.

1995 • 295 citations

Regulation of leukocyte migration by activation of the leukocyte adhesion molecule-1 (LAM-1) selectin

1991 • 294 citations

Structure of the O-Glycans in GlyCAM-1, an Endothelial-derived Ligand for L-selectin

1995 • 291 citations

Rapid G protein-regulated activation event involved in lymphocyte binding to high endothelial venules.

1993 • 271 citations

T-cell memory: the connection between function, phenotype and migration pathways

1991 • 271 citations

Peyer's patch-specific lymphocyte homing receptors consist of a VLA-4-like alpha chain associated with either of two integrin beta chains, one of which is novel.

1989 • 270 citations

Sulfation-dependent recognition of high endothelial venules (HEV)-ligands by L-selectin and MECA 79, and adhesion-blocking monoclonal antibody.

1994 • 267 citations

Biology of chemokine and classical chemoattractant receptors: differential requirements for adhesion-triggering versus chemotactic responses in lymphoid cells.

1996 • 265 citations

Chemokines regulate cellular polarization and adhesion receptor redistribution during lymphocyte interaction with endothelium and extracellular matrix. Involvement of cAMP signaling pathway.

1995 • 265 citations

Requirements for hyaluronic acid binding by CD44: a role for the cytoplasmic domain and activation by antibody.

1992 • 261 citations

Differences in the migration of B and T lymphocytes: organ-selective localization in vivo and the role of lymphocyte-endothelial cell recognition.

1982 • 257 citations

Tissue‐specific migration pathways by phenotypically distinct subpopulations of memory T cells

1992 • 255 citations

Selective expression of integrin alpha 4 beta 7 on a subset of human CD4+ memory T cells with Hallmarks of gut-trophism.

1993 • 254 citations

Molecular cloning of a cDNA encoding CD34, a sialomucin of human hematopoietic stem cells.

1992 • 251 citations

The mucosal vascular addressin is a tissue-specific endothelial cell adhesion molecule for circulating lymphocytes

1989 • 246 citations

CD44 is necessary for optimal contact allergic responses but is not required for normal leukocyte extravasation.

1993 • 241 citations

A developmental switch in lymphocyte homing receptor and endothelial vascular addressin expression regulates lymphocyte homing and permits CD4+ CD3- cells to colonize lymph nodes.

1996 • 240 citations

L-selectin function is required for beta 2-integrin-mediated neutrophil adhesion at physiological shear rates in vivo

1992 • 239 citations

Involvement of Sialic Acid on Endothelial Cells in Organ-Specific Lymphocyte Recirculation

1985 • 236 citations

Induction and function of vascular adhesion protein-1 at sites of inflammation.

1993 • 235 citations

Possible role for cell-surface carbohydrate-binding molecules in lymphocyte recirculation.

1983 • 232 citations

Adhesion to vascular cell adhesion molecule 1 and fibronectin. Comparison of alpha 4 beta 1 (VLA-4) and alpha 4 beta 7 on the human B cell line JY.

1992 • 232 citations

Lymphocyte homing receptors

1986 • 231 citations

L-selectin (CD62L) cross-linking signals neutrophil adhesive functions via the Mac-1 (CD11b/CD18) beta 2-integrin.

1995 • 228 citations

Expression and regulation of β₇(βp) integrins on mouse lymphocytes: Relevance to the mucosal immune system

1991 • 222 citations

Lymphocyte Adherence to High Endothelial Venules: Characterization of a Modified in Vitro Assay, and Examination of the Binding of Syngeneic and Allogeneic Lymphocyte Populations

1979 • 215 citations

Two distinct pools of recirculating T lymphocytes: migratory characteristics of nodal and intestinal T lymphocytes.

1977 • 213 citations

EFFECT OF GLYCOSIDASES ON THE FATE OF TRANSFUSED LYMPHOCYTES

1964 • 212 citations

Chemokines regulate T cell adherence to recombinant adhesion molecules and extracellular matrix proteins.

1996 • 211 citations

An anti-platelet-endothelial cell adhesion molecule-1 antibody inhibits leukocyte extravasation from mesenteric microvessels in vivo by blocking the passage through the basement membrane.

1996 • 198 citations

Membrane proximal cleavage of L-selectin: identification of the cleavage site and a 6-kD transmembrane peptide fragment of L-selectin.

1994 • 198 citations

Detection and spatial distribution of the beta 2 integrin (Mac-1) and L-selectin (LECAM-1) adherence receptors on human neutrophils by high-resolution field emission SEM.

1993 • 195 citations

The P-selectin Glycoprotein Ligand Functions as a Common Human Leukocyte Ligand for P- and E-selectins

1995 • 195 citations

Phosphomannosyl receptors may participate in the adhesive interaction between lymphocytes and high endothelial venules.

1984 • 194 citations

Sophisticated strategies for information encounter in the lymph node: the reticular network as a conduit of soluble information and a highway for cell traffic.

1996 • 192 citations

Differential expression of lymphocyte homing receptors by human memory/effector T cells in pulmonary versus cutaneous immune effector sites

1994 • 192 citations

A fundamental subdivision of circulating lymphocytes defined by adhesion to mucosal addressin cell adhesion molecule-1. Comparison with vascular cell adhesion molecule-1 and correlation with beta 7 integrins and memory differentiation.

1996 • 191 citations

6'-Sulfated Sialyl Lewis x Is a Major Capping Group of GlyCAM-1

1994 • 191 citations

Signaling Functions of L-selectin

1995 • 190 citations

Global vascular expression of murine CD34, a sialomucin-like endothelial ligand for L-selectin

1994 • 185 citations

Entry of naive CD4 T cells into peripheral lymph nodes requires L-selectin.

1994 • 182 citations

Specific Cell-Adhesion Mechanisms Determining Migration Pathways of Recirculating Lymphocytes

1987 • 181 citations

Lymphocyte emigration from high endothelial venules in rat lymph nodes.

1976 • 180 citations

Neutrophils use both shared and distinct mechanisms to adhere to selectins under static and flow conditions.

1995 • 180 citations

The cytoplasmic domain of L-selectin interacts with cytoskeletal proteins via alpha-actinin: receptor positioning in microvilli does not require interaction with alpha-actinin.

1995 • 177 citations

The flow of blood to lymph nodes and its relation to lymphocyte traffic and the immune response.

1977 • 173 citations

Receptors involved in lymphocyte homing: relationship between a carbohydrate-binding receptor and the MEL-14 antigen.

1987 • 171 citations

A two-step adhesion cascade for T cell/endothelial cell interactions under flow conditions.

1994 • 168 citations

Chemokines and serpentines: the molecular biology of chemokine receptors

1993 • 167 citations

Identification of the Sulfated Monosaccharides of GlyCAM-1, an Endothelial-Derived Ligand for L-Selectin

1994 • 166 citations

A homing receptor-IgG chimera as a probe for adhesive ligands of lymph node high endothelial venules.

1990 • 162 citations

Sialomucin CD34 is the major L-selectin ligand in human tonsil high endothelial venules.

1995 • 161 citations

Metalloprotease and serine protease are involved in cleavage of CD43, CD44, and CD16 from stimulated human granulocytes. Induction of cleavage of L-selectin via CD16.

1994 • 160 citations

Cloning from purified high endothelial venule cells of hevin, a close relative of the antiadhesive extracellular matrix protein SPARC

1995 • 160 citations

Activation of human neutrophils through L-selectin and Mac-1 molecules.

1995 • 159 citations

Germinal center B cells lack homing receptors necessary for normal lymphocyte recirculation.

1983 • 157 citations

Studies on the structure and permeability of the microvasculature in normal rat lymph nodes.

1975 • 155 citations

The influence of afferent lymphatic vessel interruption on vascular addressin expression.

1991 • 154 citations

Distinct but overlapping epitopes are involved in alpha 4 beta 7-mediated adhesion to vascular cell adhesion molecule-1, mucosal addressin-1, fibronectin, and lymphocyte aggregation.

1994 • 154 citations

Abnormal migration of T lymphocyte clones.

1982 • 153 citations

The traffic of lymphocytes.

1969 • 153 citations

Expression of the α(1,3)Fucosyltransferase Fuc-TVII in Lymphoid Aggregate High Endothelial Venules Correlates with Expression of L-Selectin Ligands

1996 • 146 citations

Cloning and expression of mouse integrin beta p(beta 7): a functional role in Peyer's patch-specific lymphocyte homing.

1992 • 145 citations

Interferon-gamma regulates an antigen specific for endothelial cells involved in lymphocyte traffic.

1986 • 145 citations

Disappearance and reappearance of high endothelial venules and immigrating lymphocytes in lymph nodes deprived of afferent lymphatic vessels: a possible regulatory role of macrophages in lymphocyte migration

1983 • 145 citations

The C-type carbohydrate recognition domain (CRD) superfamily

1994 • 141 citations

Dual binding capacity of mucosal immunoblasts to mucosal and synovial endothelium in humans: dissection of the molecular mechanisms.

1995 • 136 citations

Mutational analysis of the membrane-proximal cleavage site of L-selectin: relaxed sequence specificity surrounding the cleavage site.

1995 • 134 citations

The immediate effect of antigens on the cell output of a lymph node.

1965 • 133 citations

How organ-specific is the migration of ‘naive’ and ‘memory’ T cells?

1996 • 132 citations

Leukocyte integrins

1995 • 132 citations

Modulation of Endothelial Cell Adhesion by Hevin, an Acidic Protein Associated with High Endothelial Venules

1996 • 132 citations

Murine platelet endothelial cell adhesion molecule (PECAM‐1)/CD31 modulates β₂ integrins on lymphokine‐activated killer cells

1993 • 131 citations

Rapid activation‐independent shedding of leukocyte L‐selectin induced by cross‐linking of the surface antigen

1992 • 130 citations

CD34-deficient mice have reduced eosinophil accumulation after allergen exposure and show a novel crossreactive 90-kD protein

1996 • 130 citations

Human mucosal addressin cell adhesion molecule-1 (MAdCAM-1) demonstrates structural and functional similarities to the alpha 4 beta 7-integrin binding domains of murine MAdCAM-1, but extreme divergence of mucin-like sequences.

1996 • 128 citations

Alpha 4 beta 7 integrin mediates B cell binding to fibronectin and vascular cell adhesion molecule-1. Expression and function of alpha 4 integrins on human B lymphocytes.

1993 • 128 citations

Intravenous interleukin-8 inhibits granulocyte emigration from rabbit mesenteric venules without altering L-selectin expression or leukocyte rolling.

1993 • 127 citations

Developmental switches in the immune system

1994 • 126 citations

A role for the epidermal growth factor-like domain of P-selectin in ligand recognition and cell adhesion

1994 • 124 citations

Differential expression of homing molecules on recirculating lymphocytes from sheep gut, peripheral, and lung lymph.

1996 • 123 citations

Vascular adhesion protein 1 mediates binding of T cells to human hepatic endothelium

1996 • 119 citations

The mouse lymph node homing receptor is identical with the lymphocyte cell surface marker Ly-22: Role of the EGF domain in endothelial binding

1990 • 117 citations

Evidence that leukocyte function-associated antigen-1 is involved in recirculation and homing of human lymphocytes via high endothelial venules.

1988 • 115 citations

Human vascular adhesion protein 1 (VAP-1) is a unique sialoglycoprotein that mediates carbohydrate-dependent binding of lymphocytes to endothelial cells.

1996 • 114 citations

Specialized structure and metabolic activities of high endothelial venules in rat lymphatic tissues.

1976 • 114 citations

Phosphomannosyl-derivatized beads detect a receptor involved in lymphocyte homing.

1987 • 113 citations

The in vivo cytotoxic activity of CD8+ T cell clones correlates with their levels of expression of adhesion molecules.

1992 • 112 citations

T cell adhesion to endothelium: the FRC conduit system and other anatomic and molecular features which facilitate the adhesion cascade in lymph node

1993 • 112 citations

High endothelial venule binding as a predictor of the dissemination of passaged murine lymphomas.

1987 • 111 citations

A comparison of lymphocyte migration through intestinal lymph nodes, subcutaneous lymph nodes, and chronic inflammatory sites of sheep

1980 • 109 citations

Glycosylation-dependent cell adhesion molecule 1 (GlyCAM 1) mucin is expressed by lactating mammary gland epithelial cells and is present in milk.

1993 • 108 citations

An in vitro model of lymphocyte homing. I. Characterization of the interaction between thoracic duct lymphocytes and specialized high-endothelial venules of lymph nodes.

1977 • 107 citations

Regulation of leukocyte adhesion molecule-1 (TQ1, Leu-8) expression and shedding by normal and malignant cells.

1991 • 102 citations

The human intraepithelial lymphocyte marker HML‐1 is an integrin consisting of a β7 subunit associated with a distinctive α chain

1992 • 101 citations

Dynamics of Lymphocyte-Endothelial Interactions in Vivo

1986 • 100 citations

Differences in in vivo distribution and homing of T cell subsets to mucosal vs nonmucosal lymphoid organs.

1983 • 99 citations

Transforming growth factor‐β₁‐induced expression of the mucosa‐related integrin α_E on lymphocytes is not associated with mucosa‐specific homing

1995 • 97 citations

Intravenously injected sialidase inactivates attachment sites for lymphocytes on high endothelial venules.

1989 • 95 citations

Homing receptors reexamined: mouse LECAM-1 (MEL-14 antigen) is involved in lymphocyte migration into gut-associated lymphoid tissue

1991 • 92 citations

Regulation of lymphocyte homing. I. Alterations in homing receptor expression and organ-specific high endothelial venule binding of lymphocytes upon activation.

1988 • 90 citations

The alpha 4 integrin chain is a ligand for alpha 4 beta 7 and alpha 4 beta 1.

1995 • 87 citations

The ?7 integrins in mucosal homing and retention

1995 • 87 citations

Cytokine Production (IL-1α, IL-1β, and TNFα) and Endothelial Cell Activation (ELAM-1 and HLA-DR) in Reactive Lymphadenitis, Hodgkin's Disease, and in Non-Hodgkin's Lymphomas: An Immunocytochemical Study

1990 • 85 citations

Demonstration that a lectin-like receptor (gp90MEL) directly mediates adhesion of lymphocytes to high endothelial venules of lymph nodes.

1989 • 85 citations

Human neutrophils release the Leu-8 lymph node homing receptor during cell activation

1990 • 80 citations

Migration of lymphoblasts in the rat. Preferential localization of DNA-synthesizing lymphocytes in particular lymph nodes and other sties.

1980 • 79 citations

Expression and cell distribution of the intercellular adhesion molecule, vascular cell adhesion molecule, endothelial leukocyte adhesion molecule, and endothelial cell adhesion molecule (CD31) in reactive human lymph nodes and in Hodgkin's disease.

1992 • 75 citations

Association of murine CD31 with transmigrating lymphocytes following antigenic stimulation.

1992 • 74 citations

Structural requirements for mucosal vascular addressin binding to its lymphocyte receptor alpha 4 beta 7. Common themes among integrin-Ig family interactions.

1996 • 74 citations

Lymphocyte binding to vascular endothelium in inflamed skin revisited: a central role for vascular adhesion protein‐1 (VAP‐1)

1996 • 71 citations

Vcam-1 is a cs1 peptide-inhibitable adhesion molecule expressed by lymph node high endothelium

1993 • 71 citations

Untersuchungen über die Capillaren und postcapillären Venen lymphatischer Organe

1925 • 71 citations

Dendritic cells from different tissues induce production of different T cell cytokine profiles

1996 • 70 citations

Regulation of adhesion molecule expression by CD8 T cells in vivo. II. Expression of L-selectin (CD62L) by memory cytolytic T cells responding to minor histocompatibility antigens.

1994 • 70 citations

Expression of GlyCAM-1, an endothelial ligand for L-selectin, is affected by afferent lymphatic flow.

1993 • 69 citations

High levels of the shed form of L-selectin are present in patients with acute leukemia and inhibit blast cell adhesion to activated endothelium

1994 • 66 citations

The intrinsic migratory capacity of memory T cells contributes to their accumulation in rheumatoid synovium

1992 • 66 citations

Tissue-specific migration of lymphocytes: a key role for Th1 and Th2 cells ?

1996 • 66 citations

Migration of lymphocytes across specialized vascular endothelium : V. Production of a sulphated macromolecule by high endothelial cells in lymph nodes*

1982 • 66 citations

Identification of a soluble form of a ligand for the lymphocyte homing receptor.

1992 • 64 citations

An in vitro Model of Lymphocyte Homing

1977 • 63 citations

Possible role of surface Ig in non-random recirculation of small lymphocytes

1976 • 63 citations

Selective modulation of the expression of L-selectin ligands by an immune response

1995 • 62 citations

Light microscopic, histochemical and ultrastructural studies of human lymph node paracortical venules.

1983 • 60 citations

Light and electron microscopic studies of the paracortical post-capillary high-endothelial venules

1971 • 60 citations

The ontogeny of human lymphocyte recirculation: high endothelial cell antigen (HECA‐452) and CD44 homing receptor expression in the development of the immune system

1990 • 55 citations

Subsets of sialylated, sulfated mucins of diverse origins are recognized by L-selectin. Lack of evidence for unique oligosaccharide sequences mediating binding

1996 • 55 citations

Histological and histochemical study of high endothelium of post‐capillary veins of the lymph node

1959 • 55 citations

THE LIFE-HISTORY OF LYMPHOCYTES

1959 • 55 citations

Afferent Lymph and Lymph Borne Cells: Their Influence on Lymph Node Function

1984 • 53 citations

Phenotypic analysis of thymocytes that express homing receptors for peripheral lymph nodes.

1986 • 53 citations

Interferon-alpha induces the expression of the L-selectin homing receptor in human B lymphoid cells.

1993 • 51 citations

Biosynthesis of GlyCAM-1, a Mucin-like Ligand for L-Selectin

1995 • 51 citations

Memory B cells express a phenotype consistent with migratory competence after secondary but not short-term primary immunization

1988 • 49 citations

Endothelien als Phagocyten (aus den Lymphdrüsen von Macacus cynomolgus)

1898 • 48 citations

Bacterial superantigens induce rapid and T cell receptor V beta-selective down-regulation of L-selectin (gp90Mel-14) in vivo.

1993 • 47 citations

L-selectin expression differentiates T cells isolated from different lymphoid tissues in cattle but does not correlate with memory.

1992 • 46 citations

Coordinate expression of β1 and β2 integrin “activation” epitopes during T cell responses in secondary lymphoid tissue

1993 • 45 citations

L- and E-selectin can recognize the same naturally occurring ligands on high endothelial venules.

1993 • 45 citations

The structure and development of the lymphatic tissue in the intestine of the albino rat

1935 • 44 citations

Organization, regulatory sequences, and alternatively spliced transcripts of the mucosal addressin cell adhesion molecule-1 (MAdCAM-1) gene.

1995 • 43 citations

Expression of endothelial adhesion molecules in vivo. Increased endothelial ICAM-2 expression in lymphoid malignancies.

1992 • 43 citations

Different forms of human vascular adhesion protein‐1 (VAP‐1) in blood vessels in vivo and in cultured endothelial cells: implications for lymphocyte‐endothelial cell adhesion models

1995 • 43 citations

Regulation of lymphoblast traffic and localization in mucosal tissues, with emphasis on IgA.

1983 • 42 citations

Use of synthetic peptides to probe lymphocyte- high endothelial cell interactions. Lymphocytes recognize a ligand on the endothelial surface which contains the CS1 adhesion motif

1990 • 41 citations

Lymphocyte adhesion to high endothelium is mediated by two β1 integrin receptors for fibronectin, α4β1 and α5β1

1992 • 40 citations

Developmental regulation of vascular addressin expression: a possible role for site-associated environments

1993 • 37 citations

The lymphocyte — a disgraceful gap in medical knowledge

1996 • 37 citations

Correlation between serum level of soluble L‐selectin and leukocyte count in chronic myeloid and lymphocytic leukemia and during bone marrow transplantation

1993 • 36 citations

Random entry of circulating lymphocyte subsets into peripheral lymph nodes and Peyer's patches: No evidence in vivo of a tissue‐specific migration of B and T lymphocytes at the level of high endothelial venules

1992 • 33 citations

Studies on the lymphocytes of sheep. I. Recirculation of lymphocytes through peripheral lymph nodes and tissues

1976 • 32 citations

Ueber Phagocytose und die Abfuhrwege der Leucocyten in den Lymphdrüsen

1899 • 32 citations

CD4⁺lymphocytes are extracted from blood by peripheral lymph nodes at different rates from other T cell subsets and B cells

1988 • 31 citations

Cloning of a rat homologue of mouse GlyCAM 1 reveals conservation of structural domains

1993 • 30 citations

Blood group-related oligosaccharides are ligands in cell-adhesion events

1992 • 29 citations

Regulation of Tissue-selective T-Lymphocyte Homing Receptors during the Virgin to Memory/Effector Cell Transition in Human Secondary Lymphoid Tissues

1993 • 29 citations

Ultrastructural localization of the intercellular adhesion molecule (ICAM-1) on the cell surface of high endothelial venules in lymph nodes

1996 • 29 citations

Metabolic Studies of High‐Walled Endothelium of Postcapillary Venules in Rat Lymph Nodes

1980 • 28 citations

The function of high endothelial venules in mouse lymph nodes stimulated by oxazolone.

1990 • 26 citations

Interaction of B and T lymphocyte subsets with high endothelial venules in the rat: binding in vitro does not reflect homing in vivo

1995 • 25 citations

Cellular, Genetic, and Evolutionary Aspects of Lymphocyte Interactions with High‐Endothelial Venules

1980 • 25 citations

Arteriovenous shunting in the lymph node before and after antigenic stimulus.

1979 • 25 citations

Glycoconjugates from high endothelial cells: I. Partial characterization of a sulphated glycoconjugate from the high endothelial cells of rat lymph nodes

1983 • 24 citations

Regulation of L-selectin mRNA in Jurkat cells. Opposing influences of calcium- and protein kinase C-dependent signaling pathways.

1995 • 24 citations

The Functional Activity of High Endothelial Venules: A Role for the Subcapsular Sinus Macrophages in the Lymph NodeREIN

1991 • 24 citations

Relationships between changes in blood flow and lymphocyte migration induced by antigen.

1980 • 23 citations

An essay on lymphocyte circulation and the gut.

1980 • 17 citations

Reassortment of Cell Populations within the Lymphoid Apparatus of the Sheep

1980 • 17 citations

Activation of high endothelial venules in peripheral lymph nodes. The involvement of interferon-gamma

1994 • 14 citations

Triggering of L-selectin (gp90^MEL-14) induces homotypic lymphocyte adhesion by a mechanism independent of LFA-1

1993 • 12 citations

Reversible stimulation of lymphocyte motility by cultured high endothelial cells: mediation by L-selectin.

1995 • 12 citations

Expression of the mC26 Gene Encoding GlyCAM-1 in the Lactating Mouse Mammary Gland

1993 • 12 citations

In Vivo Immunology

1994 • 12 citations

The bovine PP3 gene is homologous to the murine GlyCAM 1 gene

1996 • 11 citations

Macrophages and the activity of high endothelial venules. The effect of interferon‐γ

1990 • 10 citations

The phenotype of murine Langerhans cells from skin to lymph node.

1993 • 10 citations

The kinetics of migration of murine CD4 and CD8 lymphocytes in vivo.

1990 • 9 citations

Functional Capacities of High Endothelial Venules Appear not to be Controlled by Recirculating Lymphocytes

1990 • 7 citations

High endothelial venules: regulation of activity and specificity.

1993 • 3 citations

Vascular Addressin Expression in Peyer’S Patches: an in Vivo Study of Site-Associated Regulation

1994 • 2 citations