Selectin ligands.

Leukocyte-endothelial cell recognition: Three (or more) steps to specificity and diversity

1991 • 2,806 citations

ELAM-1 Mediates Cell Adhesion by Recognition of a Carbohydrate Ligand, Sialyl-Le ^x

1990 • 1,315 citations

Selectins: Interpreters of Cell-Specific Carbohydrate Information During Inflammation

1992 • 1,255 citations

STRUCTURE AND FUNCTION OF THE MANNOSE 6-PHOSPHATE/INSULINLIKE GROWTH FACTOR II RECEPTORS

1992 • 1,056 citations

Recognition by Elam-1 of the Sialyl-Le ^x Determinant on Myeloid and Tumor Cells

1990 • 976 citations

Selectins.

1993 • 869 citations

ELAM-1 is an adhesion molecule for skin-homing T cells

1991 • 843 citations

Expression cloning of a functional glycoprotein ligand for P-selectin

1993 • 734 citations

ZONA PELLUCIDA GLYCOPROTEINS

1988 • 730 citations

ELAM-1-dependent cell adhesion to vascular endothelium determined by a transfected human fucosyltransferase cDNA

1990 • 712 citations

Why are proteins O-glycosylated?

1990 • 708 citations

The three members of the selectin receptor family recognize a common carbohydrate epitope, the sialyl Lewis(x) oligosaccharide

1992 • 698 citations

An endothelial ligand for L-Selectin is a novel mucin-like molecule

1992 • 660 citations

Physiological and Molecular Mechanisms of Lymphocyte Homing

1992 • 655 citations

Adhesion molecules controlling lymphocyte migration

1989 • 654 citations

Immunohistologic and functional characterization of a vascular addressin involved in lymphocyte homing into peripheral lymph nodes.

1988 • 639 citations

Binding of L-Selectin to the Vascular Sialomucin CD34

1993 • 629 citations

The neutrophil selectin LECAM-1 presents carbohydrate ligands to the vascular selectins ELAM-1 and GMP-140

1991 • 592 citations

The cutaneous lymphocyte antigen is a skin lymphocyte homing receptor for the vascular lectin endothelial cell-leukocyte adhesion molecule 1.

1991 • 557 citations

Recurrent Severe Infections Caused by a Novel Leukocyte Adhesion Deficiency

1992 • 555 citations

Contribution of carbohydrate antigens sialyl Lewis A and sialyl Lewis X to adhesion of human cancer cells to vascular endothelium.

1993 • 547 citations

L-selectin-mediated lymphocyte rolling on MAdCAM-1

1993 • 540 citations

Identification of a specific glycoprotein ligand for P-selectin (CD62) on myeloid cells.

1992 • 519 citations

CD62 and endothelial cell-leukocyte adhesion molecule 1 (ELAM-1) recognize the same carbohydrate ligand, sialyl-Lewis x.

1991 • 505 citations

Heparin oligosaccharides bind L- and P-selectin and inhibit acute inflammation

1993 • 499 citations

A carbohydrate domain common to both sialyl Le(a) and sialyl Le(X) is recognized by the endothelial cell leukocyte adhesion molecule ELAM-1

1991 • 480 citations

Lectin-like cell adhesion molecule 1 mediates leukocyte rolling in mesenteric venules in vivo

1991 • 473 citations

Chemotactic factors regulate lectin adhesion molecule 1 (LECAM-1)-dependent neutrophil adhesion to cytokine-stimulated endothelial cells in vitro.

1991 • 439 citations

Increased expression of sialyl Lewisx antigen correlates with poor survival in patients with colorectal carcinoma: clinicopathological and immunohistochemical study.

1993 • 417 citations

Leukocyte adhesion molecule-1 (LAM-1, L-selectin) interacts with an inducible endothelial cell ligand to support leukocyte adhesion.

1991 • 406 citations

Insight into E-selectin/ligand interaction from the crystal structure and mutagenesis of the lec/EGF domains

1994 • 397 citations

Activation-independent binding of human memory T cells to adhesion molecule ELAM-1

1991 • 379 citations

PADGEM-dependent adhesion of platelets to monocytes and neutrophils is mediated by a lineage-specific carbohydrate, LNF III (CD15)

1990 • 367 citations

ELFT: A gene that directs the expression of an ELAM-1 ligand

1990 • 338 citations

Sulphation requirement for GlyCAM-1, an endothelial ligand for L-selectin

1993 • 330 citations

Protective effects of oligosaccharides in P-selectin-dependent lung injury

1993 • 319 citations

Human monocytes bind to two cytokine-induced adhesive ligands on cultured human endothelial cells: endothelial-leukocyte adhesion molecule-1 and vascular cell adhesion molecule-1

1991 • 318 citations

Identification of a carbohydrate-based endothelial ligand for a lymphocyte homing receptor.

1991 • 308 citations

The human peripheral lymph node vascular addressin is a ligand for LECAM-1, the peripheral lymph node homing receptor.

1991 • 307 citations

CD62/P-selectin recognition of myeloid and tumor cell sulfatides

1991 • 304 citations

Structural and functional characterization of monomeric soluble P-selectin and comparison with membrane P-selectin

1993 • 297 citations

Molecular cloning of a human fucosyltransferase gene that determines expression of the Lewis x and VIM-2 epitopes but not ELAM-1-dependent cell adhesion.

1991 • 281 citations

Characterization of a specific ligand for P-selectin on myeloid cells. A minor glycoprotein with sialylated O-linked oligosaccharides

1993 • 274 citations

GMP-140 binds to a glycoprotein receptor on human neutrophils: evidence for a lectin-like interaction.

1991 • 247 citations

Structural requirements for the carbohydrate ligand of E-selectin.

1991 • 242 citations

A malaria invasion receptor, the 175-kilodalton erythrocyte binding antigen of Plasmodium falciparum recognizes the terminal Neu5Ac(alpha 2-3)Gal- sequences of glycophorin A.

1992 • 240 citations

Novel sulfated ligands for the cell adhesion molecule E-selectin revealed by the neoglycolipid technology among O-linked oligosaccharides on an ovarian cystadenoma glycoprotein

1992 • 237 citations

Carbohydrate ligands for endothelial-leukocyte adhesion molecule 1.

1991 • 236 citations

Involvement of Sialic Acid on Endothelial Cells in Organ-Specific Lymphocyte Recirculation

1985 • 236 citations

Human eosinophil adherence to vascular endothelium mediated by binding to vascular cell adhesion molecule 1 and endothelial leukocyte adhesion molecule 1.

1991 • 233 citations

Lymphocyte Homing

1989 • 227 citations

Selectins

1994 • 207 citations

Biochemistry of carbohydrate‐protein interaction ¹

1992 • 205 citations

GMP-140 binding to neutrophils is inhibited by sulfated glycans.

1991 • 202 citations

Identification of a glycoprotein ligand for E-selectin on mouse myeloid cells.

1993 • 201 citations

Calcium-Dependent Heparin-Like Ligands For L-Selectin in Nonlymphoid Endothelial Cells

1993 • 201 citations

In vivo behavior of neutrophils from two patients with distinct inherited leukocyte adhesion deficiency syndromes.

1993 • 199 citations

The HNK-1 reactive sulfoglucuronyl glycolipids are ligands for L-selectin and P-selectin but not E-selectin.

1993 • 182 citations

Monospecific and common glycoprotein ligands for E- and P-selectin on myeloid cells.

1994 • 179 citations

Comparison of L-selectin and E-selectin ligand specificities: The L-selectin can bind the E-selectin ligands Sialyl Lex and Sialyl Lea

1992 • 179 citations

Antibodies against human neutrophil LECAM-1 (LAM-1/Leu-8/DREG-56 antigen) and endothelial cell ELAM-1 inhibit a common CD18-independent adhesion pathway in vitro

1991 • 178 citations

P-selectin mediates adhesion of platelets to neuroblastoma and small cell lung cancer.

1993 • 177 citations

The selectin GMP-140 binds to sialylated, fucosylated lactosaminoglycans on both myeloid and nonmyeloid cells.

1991 • 175 citations

Sialyl Lewisx-containing oligosaccharide attenuates myocardial reperfusion injury in cats.

1994 • 174 citations

High affinity binding of the leucocyte adhesion molecule L-selectin to 3′-sulphated-Lea and -Lex oligosaccharides and the predominance of sulphate in this interaction demonstrated by binding studies with a series of lipid-linked oligosaccharides

1992 • 173 citations

CD66 nonspecific cross-reacting antigens are involved in neutrophil adherence to cytokine-activated endothelial cells.

1992 • 168 citations

Identification of an E-selectin region critical for carbohydrate recognition and cell adhesion [published erratum appears in J Cell Biol 1993 Feb;120(4):1071]

1992 • 166 citations

Higher-affinity oligosaccharide ligands for E-selectin.

1993 • 166 citations

Structure--function studies on selectin carbohydrate ligands. Modifications to fucose, sialic acid and sulphate as a sialic acid replacement

1993 • 164 citations

A homing receptor-IgG chimera as a probe for adhesive ligands of lymph node high endothelial venules.

1990 • 162 citations

L-selectin mediates neutrophil rolling in inflamed venules through sialyl LewisX-dependent and -independent recognition pathways

1993 • 162 citations

P-selectin and E-selectin. Distinct but overlapping leukocyte ligand specificities.

1992 • 160 citations

Monocyte attachment to activated human vascular endothelium in vitro is mediated by leukocyte adhesion molecule-1 (L-selectin) under nonstatic conditions.

1992 • 154 citations

Role of selectins, a new family of adhesion molecules, in ischaemia-reperfusion injury

1994 • 154 citations

Role of H1 receptors and P-selectin in histamine-induced leukocyte rolling and adhesion in postcapillary venules.

1994 • 151 citations

P- and E-selectin use common sites for carbohydrate ligand recognition and cell adhesion.

1993 • 150 citations

Sulfated blood group Lewis(a). A superior oligosaccharide ligand for human E-selectin.

1994 • 145 citations

Sulfated Glycolipids Are Ligands for a Lymphocyte Homing Receptor, L-Selectin (LECAM-1), Binding Epitope in Sulfated Sugar Chain

1993 • 142 citations

Selectin GMP-140 (CD62; PADGEM) binds to sialosyl-Lea and sialosyl-Lex, and sulfated glycans modulate this binding

1991 • 134 citations

Spectrum of sialylated and nonsialylated fuco-oligosaccharides bound by the endothelial-leukocyte adhesion molecule E-selectin. Dependence of the carbohydrate binding activity on E-selectin density.

1992 • 130 citations

E-selectin-dependent adhesion efficiency of colonic carcinoma cells is increased by genetic manipulation of their cell surface lysosomal membrane glycoprotein-1 expression levels

1993 • 130 citations

A role for the epidermal growth factor-like domain of P-selectin in ligand recognition and cell adhesion

1994 • 124 citations

Transport and sorting of membrane lipids

1993 • 123 citations

Inhibition of selectin-dependent tumor cell adhesion to endothelial cells and platelets by blocking O-glycosylation of these cells

1992 • 122 citations

Cleavage of the cell-surface O-sialoglycoproteins CD34, CD43, CD44, and CD45 by a novel glycoprotease from Pasteurella haemolytica.

1992 • 121 citations

Protective effects of sialylated oligosaccharides in immune complex-induced acute lung injury.

1993 • 111 citations

Evidence for endocytosis of E‐selectin in human endothelial cells

1992 • 111 citations

Glycosylation-dependent cell adhesion molecule 1 (GlyCAM 1) mucin is expressed by lactating mammary gland epithelial cells and is present in milk.

1993 • 108 citations

Adhesion protein GMP140 inhibits superoxide anion release by human neutrophils.

1991 • 107 citations

Requirement for sialic acid on neutrophils in a GMP-140 (PADGEM) mediated adhesive interaction with activated platelets

1990 • 102 citations

Homing receptors on human and rodent lymphocytes--evidence for a conserved carbohydrate-binding specificity

1987 • 100 citations

Bovine gamma/delta T cells bind E-selectin via a novel glycoprotein receptor: first characterization of a lymphocyte/E-selectin interaction in an animal model.

1993 • 99 citations

Sulfated glycolipids and cell adhesion

1988 • 99 citations

P-selectin (CD62) binds to subpopulations of human memory T lymphocytes and natural killer cells

1992 • 99 citations

Neutrophils, monocytes, and lymphocytes bind to cytokine-activated kidney glomerular endothelial cells through L-selectin (LAM-1) in vitro.

1992 • 98 citations

Cell surface lectins in the immune system

1993 • 97 citations

Recombinant E-selectin-protein mediates tumor cell adhesion via Sialyl-Lea and sialyl-Lex

1992 • 95 citations

Expression of alpha-(1,3)-fucosyltransferases which synthesize sialyl Le(x) and sialyl Le(a), the carbohydrate ligands for E- and P-selectins,in human malignant cell lines.

1993 • 88 citations

The vascular E-selectin binds to the leukocyte integrins CD11/CD18

1993 • 86 citations

A distinct type of sialyl Lewis X antigen defined by a novel monoclonal antibody is selectively expressed on helper memory T cells

1993 • 82 citations

Molecular mechanisms underlying lymphocyte recirculation. III. Characterization of the LECAM-1 (L-selectin)-dependent adhesion pathway in rats.

1993 • 82 citations

Structural study of the sugar chains of human leukocyte cell adhesion molecules CD11/CD18

1991 • 79 citations

Requirement for sialic acid on the endothelial ligand of a lymphocyte homing receptor.

1990 • 77 citations

Further characterization of the interaction between L-selectin and its endothelial ligands

1992 • 76 citations

Characterization of human platelet GMP-140 as a heparin-binding protein

1989 • 75 citations

CD62/P-Selectin Binding Sites for Myeloid Cells and Sulfatides Are Overlapping

1994 • 74 citations

Enhanced interaction of L-selectin with the high endothelial venule ligand via selectively oxidized sialic acids.

1993 • 73 citations

Evolutionary conservation of tissue-specific lymphocyte-endothelial cell recognition mechanisms involved in lymphocyte homing.

1988 • 70 citations

Interaction of P-selectin (CD62) and its cellular ligand: Analysis of critical residues

1993 • 66 citations

The complement binding-like domains of the murine homing receptor facilitate lectin activity.

1991 • 64 citations

Common tetrasaccharide epitope NeuAc alpha 2–>3Gal beta 1–>3(Neu-Ac alpha 2–>6)GalNAc, presented by different carrier glycosylceramides or O-linked peptides, is recognized by different antibodies and ligands having distinct specificities.

1994 • 64 citations

Differential expression of an E-selectin ligand (SLex) by two Chinese hamster ovary cell lines transfected with the same alpha (1,3)-fucosyltransferase gene (ELFT).

1994 • 63 citations

A lymphocyte homing receptor (L-selectin) mediates the in vitro attachment of lymphocytes to myelinated tracts of the central nervous system.

1991 • 63 citations

Consensus repeat domains of E-selectin enhance ligand binding.

1994 • 54 citations

Role of ELAM‐1 in Adhesion of Monocytes to Activated Human Endothelial Cells

1992 • 51 citations

L- and E-selectin can recognize the same naturally occurring ligands on high endothelial venules.

1993 • 45 citations

Rotaviruses preferentially bind O-linked sialylglycoconjugates and sialomucins

1993 • 43 citations

The glycoprotease of Pasteurella haemolytica A1 eliminates binding of myeloid cells to P-selectin but not to E-selectin

1992 • 42 citations

Species differences in the expression of carbohydrate differentiation antigens on mammalian blood cells revealed by immunofluorescence with monoclonal antibodies

1984 • 42 citations

Characterization of the E-selectin ligand on NK cells.

1994 • 35 citations

Structure and dynamics of mucin-like glycopeptides. Examination of peptide chain expansion and peptide-carbohydrate interactions by stochastic dynamics simulations

1993 • 34 citations

Oligosaccharide–Protein Interactions: A Three‐Dimensional View

2007 • 29 citations

Phosphorylation of surface E‐selectin and the effect of soluble ligand (Sialyl Lewis^x) on the half‐life of E‐selectin

1993 • 28 citations

Multi-recognition capability of E-selectin in a dynamic flow system, as evidenced by differential effects of sialidases and anti-carbohydrate antibodies on selectin-mediated cell adhesion at low vs. high wall shear stress: A preliminary note

1992 • 23 citations

The ligand recognized by ELAM‐1 on HL60 cells is not carried by N‐linked oligosaccharides

1991 • 20 citations

Reactivity of Mucin-Specific Lectin fromSambucus sieboldianawith Simple Sugars, Normal Mucins and Tumor-Associated Mucins. Comparison with Other Lectins

1991 • 10 citations